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Sickle Cell Disease
Sickle cell disease (SCD) is a monogenetic disease with a polygenic phenotype. Stroke and other cerebrovascular diseases are still among the most...
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Surgery for Sickle Cell Retinopathy
This chapter discusses the indications, surgical considerations, and techniques for managing proliferative sickle cell-related vitreoretinal...
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Sickle Cell Retinopathy
Sickle cell disease is the most common inherited hematological disorder worldwide. Ocular manifestations of SCD include sickle cell retinopathy (SCR)...
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Sickle Cell Anemia and Related Hemoglobinopathies
Sickle cell disease (SCD)is the most common structural hemoglobinopathies resulting from inherited abnormalities of globin chain synthesis. This...
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Sickle Cell Anemia and Ulcer
Sickle cell hemoglobin (HbS) is a variant of adult hemoglobin due to mutation of beta chain of globin, which leads to substitution of valine amino...
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Non-Sickle Cell Structural Hemoglobinopathies
Hemoglobinopathies are common inherited diseases around the world. There are many structural hemoglobin variants. Examples of non-sickle cell...
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Hemoglobinopathies (Sickle Cell Disease and Thalassemia)
Hematopoietic cell transplantation (HCT) using an HLA-matched sibling donor is a well-established curative therapy for pediatric patients with sickle...
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The Kidney in Sickle Cell Disease
Early in life, patients with sickle cell anemia are at high risk for the development of hyposthenuria, enuresis, and hyperfiltration. Importantly,...
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Comparative assessment of quality of life among adolescents with sickle cell disease and sickle cell trait: evidence from Odisha, India
The present study aims to assess the quality of life (QOL) of adolescents with sickle cell disease (SCD) and sickle cell trait (SCT) in hard-to-reach...
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How I Manage Sickle Cell Retinopathy
Purpose of ReviewWe describe our current approach to sickle cell retinopathy screening, evaluation, treatment, and surgical intervention.
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New Insights into Clinical Management for Sickle Cell Disease: Uncovering the Significant Pathways Affected by the Involvement of Sickle Cell Disease
One of the severe monogenic conditions with the highest prevalence in the globe is sickle cell disease. Although the significance of chronic anemia,...
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Sickle Cell Retinopathy
Sickle cell retinopathy prevalence increases with age and occurs earlier in patients with hemoglobin SC than with hemoglobin SS or SThalassemia...
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Knowledge and attitude towards sickle cell anemia among care givers of paediatric sickle cell patients at a tertiary hospital in Eastern Uganda: a cross sectional study
ObjectiveTo explore the knowledge and attitude towards sickle cell disease (SCD) among care givers of paediatric sickle cell patients at Mbale...
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Social Science Research and Sickle Cell Disorders
Social science research on sickle cell disorders (SCD), recessively inherited blood conditions, have come of age in the last twenty years from being...
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Social Science Research and Sickle Cell Disorders
Social science research on sickle cell disorders (SCD), recessively inherited blood conditions, have come of age in the last twenty years from being...
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Sickle Cell Disease
Sickle cell disease (SCD) is caused by a structurally abnormal β-globin chain, expressed exclusively in erythrocytes and incorporated in Sickle...
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Statistical Analysis of Hematological Parameters for Prediction of Sickle Cell Disease
About 30 million people worldwide are affected by the monogenic recessive -globin gene abnormality known as sickle cell disease (SCD), which is a...
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Sickle Cell Disease Management in Develo** Countries
Sickle cell disease (SCD) remains a formidable healthcare challenge in develo** countries, characterized by high prevalence, significant morbidity,...
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The Use of Natural Products in the Treatment of Sickle Cell Disease
Sickle cell disease is the world's leading inherited genetic hemoglobinopathy, originating from African peoples, characterized by the presence of...
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Risk factors associated with sickle cell retinopathy: findings from the Cooperative Study of Sickle Cell Disease
BackgroundSickle cell retinopathy (SCR) is one of the most important ocular manifestations of sickle cell disease (SCD). This study aims to assess...