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Unravelling protein corona formation on pristine and leached microplastics
Upon entering the environment, the surface properties of pristine plastics are rapidly altered due to interactions with exogenous biomolecules,...
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The protein corona from nanomedicine to environmental science
The protein corona spontaneously develops and evolves on the surface of nanoscale materials when they are exposed to biological environments,...
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Controlling the protein corona of polymeric nanocapsules: effect of polymer shell on protein adsorption
Understanding the interactions between nanocarriers and plasma proteins is essential for controlling their biological fate. Based on the reported...
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Regulating protein corona on nanovesicles by glycosylated polyhydroxy polymer modification for efficient drug delivery
The dynamic protein corona formed on nanocarriers has been revealed to strongly affect their in vivo behaviors. Precisely manipulating the formation...
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Cellular uptake and in vivo distribution of mesenchymal-stem-cell-derived extracellular vesicles are protein corona dependent
Extracellular vesicles (EVs) derived from mesenchymal stem cells are promising nanotherapeutics in liver diseases due to their regenerative and...
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A uniform data processing pipeline enables harmonized nanoparticle protein corona analysis across proteomics core facilities
Protein corona, a layer of biomolecules primarily comprising proteins, forms dynamically on nanoparticles in biological fluids and is crucial for...
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Concentration and composition of the protein corona as a function of incubation time and serum concentration: an automated approach to the protein corona
Nanoparticles in contact with proteins form a “corona” of proteins adsorbed on the nanoparticle surface. Subsequent biological responses are then...
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Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona
Nanoparticles (NPs) in biological fluids form a layer of biomolecules known as the protein corona. The protein corona has been shown to determine the...
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Endosomal sorting results in a selective separation of the protein corona from nanoparticles
The formation of the protein corona is a well-known effect when nanoparticles (NP) are exposed to biological environments. The protein corona is the...
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Drying of graphene oxide: effects on red blood cells and protein corona formation
In this work, we performed an integrated study on the physicochemical changes of graphene oxide (GO) during the drying process in terms of their...
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Fibronectin-derived protein forms a protein corona on gold nanoparticles: synthesis, Raman and optical properties of a new plasmonic nanocarrier
Synthetic fibronectin III-derived protein scaffolds represent a new generation of proteins that can overcome some clinical limitations of therapeutic...
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Mesoscopic simulations of protein corona formation on zwitterionic peptide-grafted gold nanoparticles
Understanding protein corona formation on nanoparticle surface is crucial to broad applications of nanomedicine and nanotechnologies. In this work,...
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Measurements of heterogeneity in proteomics analysis of the nanoparticle protein corona across core facilities
Robust characterization of the protein corona—the layer of proteins that spontaneously forms on the surface of nanoparticles immersed in biological...
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The in vitro gastrointestinal digestion-associated protein corona of polystyrene nano- and microplastics increases their uptake by human THP-1-derived macrophages
BackgroundMicro- and nanoplastics (MNPs) represent one of the most widespread environmental pollutants of the twenty-first century to which all...
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The Yin and Yang of the protein corona on the delivery journey of nanoparticles
Nanoparticles-based drug delivery systems have attracted significant attention in biomedical fields because they can deliver loaded cargoes to the...
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Protein corona and exosomes: new challenges and prospects
Recent advances in extracellular vesicle (EVs) detection and isolation methods have led to the development of novel therapeutic modalities. Among...
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The influence of protein corona on Graphene Oxide: implications for biomedical theranostics
Graphene-based nanomaterials have attracted significant attention in the field of nanomedicine due to their unique atomic arrangement which allows...
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Nanoparticle Protein Corona: Understanding NP Biomolecule Interactions for Safe and Informed Nanotechnological Applications Including Stress Alleviation in Plants
The use of nanotechnology in agriculture, often referred to as “phyto-nanotechnology,” has received greater attention in recent years because of its...
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Bibliometric landscape of the researches on protein corona of nanoparticles
Unclear biological fate hampers the clinical translation of nanoparticles for biomedical uses. In recent years, it is documented that the formation...
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Particle elasticity influences polymeric artificial antigen presenting cell effectiveness in vivo via CD8+ T cell activation, macrophage uptake, and the protein corona
Adoptive cell therapy (ACT) is an immunotherapy strategy for cancer that has seen widespread clinical success. During ACT, patient-derived...
