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Biologikatherapie bei schwer erkrankten Patienten mit „NSAID-exacerbated respiratory disease“ und stattgehabter ASS‑Desaktivierung
BackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) is a type‑2 inflammatory disease of the upper airways, with severe impairment of quality...
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Urinary Leukotriene E4 as a Biomarker in NSAID-Exacerbated Respiratory Disease (N-ERD): a Systematic Review and Meta-analysis
Purpose of ReviewNon-steroidal exacerbated respiratory disease (N-ERD) currently requires aspirin challenge testing for diagnosis. Urinary...
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Respiratory Exposure Tests in Aspirin Exacerbated Respiratory Disease
Purpose of reviewControlled oral provocation test with aspirin is considered the “gold standard” for diagnosing hypersensitivity to NSAIDs...
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A retrospective study on long-term efficacy of intranasal lysine-aspirin in controlling NSAID-exacerbated respiratory disease
PurposeAspirin treatment after desensitization (ATAD) represents an effective therapeutic option suitable for NSAID-exacerbated respiratory disease...
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Mast Cells in Aspirin-Exacerbated Respiratory Disease
Purpose of ReviewAspirin-exacerbated respiratory disease (AERD) is a syndrome of high type 2 inflammation and is known to critically involve mast...
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Bovine Respiratory Disease
Bovine respiratory disease (BRD) represents one of the most important diseases of rearing and veal calves with enormous impact on animal welfare and...
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Nasal Polyposis and Nonsteroidal Anti-inflammatory Drug-Exacerbated Respiratory Disease
Nonsteroidal anti-inflammatory drug-exacerbated respiratory disease (NERD) is a phenotype of nasal polyposis. The coexistence of asthma, persistent...
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Immune endoty** and gene expression profile of patients with chronic rhinosinusitis with nasal polyps in the aspirin-exacerbated respiratory disease (AERD) and the non-AERD subgroups
BackgroundChronic Rhinosinusitis (CRS) is a paranasal sinus inflammatory disease and is divided into two subgroups defined as CRS with nasal polyps...
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Acetylsalicylic acid challenge or desensitization in sensitive patients with cardiovascular disease
The use of acetylsalicylic acid (ASA) is problematic in subjects with histories of hypersensitivity reactions (HRs) to it or with cross-reactive...
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Recent Updates in Understanding NSAID Hypersensitivity
Purpose of ReviewTo provide a review of available literature regarding nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity with an emphasis...
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Medical ID use by international patients with Aspirin-Exacerbated Respiratory Disease
BackgroundPatients widely use medical identification (ID) to indicate their food and drug allergies, and chronic medical conditions. One chronic...
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Stellenwert von ASS-Provokationen beim Analgetika-Intoleranz-Syndrom
BackgroundNonsteroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD) is often characterized by a severe course of chronic...
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Samter Syndrome
Samter syndrome (also known as aspirin-exacerbated respiratory disease (AERD) or NSAID-exacerbated respiratory disease (NERD)) consists of the...
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Drug-Induced/Iatrogenic Respiratory Disease: With Emphasis on Unusual, Rare, and Emergent Drug-Induced Reactions
Drugs have been known to cause adverse respiratory reactions since at least 1880, when Sir William Osler published an autopsy report of a fatal case...
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Aspirin Desensitization in Treatment of Chronic Rhinosinusitis with Nasal Polyposis: Current Protocols and Evidence
Purpose of ReviewAspirin-exacerbated respiratory disease (AERD), or NSAID-exacerbated respiratory disease (NERD), is a heterogeneous inflammatory...
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Toxic retrobulbar neuritis due to recurrent nonsteroidal antiinflammatory drug-exacerbated respiratory disease-based chronic sinusitis in the left sphenoid sinus: a case report
BackgroundAbrupt visual impairment constitutes a medical urgency, necessitating an interdisciplinary diagnostic and therapeutic approach owing to the...
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Hat die ASS-Desaktivierung in Zeiten von Biologika noch einen Stellenwert bei chronischer Rhinosinusitis mit nasaler Polyposis?
The prevalence of analgesic intolerance syndrome (AIS), internationally known as NSAID-exacerbated respiratory disease (NERD), is reported to be...
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Multimorbidities
Chronic rhinosinusitis (CRS) is defined as a heterogeneous inflammatory disease of the mucosa of the nose and paranasal sinuses. Patients with CRS...
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Eosinophilic Chronic Rhinosinusitis with Nasal Polyps and the JESREC Study
Chronic rhinosinusitis with nasal polyps (CRSwNPs) is a heterogeneous disease. Eosinophilic CRSwNPs (ECRS) is a subgroup of CRSwNPs, associated with...
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Aspirin-Exacerbated Respiratory Disease
Aspirin-exacerbated respiratory disease (AERD) consists of asthma, eosinophilic chronic rhinosinusitis with nasal polyposis, and respiratory...