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Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine
The Ca 2+ activated Cl − channel TMEM16A (anoctamin 1; ANO1) is expressed in secretory epithelial cells of airways and intestine. Previous studies...
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Intestinal mucus components and secretion mechanisms: what we do and do not know
Damage to the colon mucus barrier, the first line of defense against microorganisms, is an important determinant of intestinal diseases such as...
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The anion exchanger slc26a3 regulates colonic mucus expansion during steady state and in response to prostaglandin E2, while Cftr regulates de novo mucus release in response to carbamylcholine
The intestinal epithelium is covered by mucus that protects the tissue from the luminal content. Studies have shown that anion secretion via the...
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The gut commensal Blautia maintains colonic mucus function under low-fiber consumption through secretion of short-chain fatty acids
Beneficial gut bacteria are indispensable for develo** colonic mucus and fully establishing its protective function against intestinal...
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Reinforcement of the intestinal mucosal barrier via mucus-penetrating PEGylated bacteria
The breakdown of the gut’s mucosal barrier that prevents the infiltration of microorganisms, inflammatory cytokines and toxins into bodily tissues...
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Mucus, Goblet Cell, Submucosal Gland
Airway mucus plays an important role in the host defense system as a physicochemical barrier by trap** foreign and endogenous substances,...
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Impact of Red Bull consumption on gastric acid and mucus secretion in Albino rats: Study of the biochemical and histopathological effects
Nowadays energy drinks (EDs) are widely used among teenagers. One of the most popular EDs in Egypt is Red Bull R (RB). The aim of this study was to...
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Bei Mu Gua Lou San facilitates mucus expectoration by increasing surface area and hydration levels of airway mucus in an air-liquid-interface cell culture model of the respiratory epithelium
BackgroundBei Mu Gua Lou San (BMGLS) is an ancient formulation known for its moisturizing and expectorant properties, but the underlying mechanisms...
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Beneficial properties of mucus in coral adaptations and ecological interactions
Coral mucus secreted by mucocytes provides a protective physicochemical and physiological barrier between coral tissue and external environmental...
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Differentiation of Pig Gastric Primary Cells into Mucus Producing Epithelial Cells
There is a growing interest in the development of in vitro models that mimic the intrinsic characteristics of cells in vivo to replace and/or reduce...
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Mucus Transpiration as the Basis for Chronic Cough and Cough Hypersensitivity
Chronic cough is characterized by a state of cough hypersensitivity. We analyze the process of transpiration, by which water appears to evaporate...
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Establishment and characterization of novel high mucus-producing lung tumoroids derived from a patient with pulmonary solid adenocarcinoma
Among mucus-producing lung cancers, invasive mucinous adenocarcinoma of the lung is a rare and unique subtype of pulmonary adenocarcinoma. Notably,...
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A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma
By incompletely understood mechanisms, type 2 (T2) inflammation present in the airways of severe asthmatics drives the formation of pathologic mucus...
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Therapeutic potential of Lianhua Qingke in airway mucus hypersecretion of acute exacerbation of chronic obstructive pulmonary disease
BackgroundLianhua Qingke (LHQK) is an effective traditional Chinese medicine used for treating acute tracheobronchitis. In this study, we evaluated...
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The risk factors involved in airway mucus plug in children with ADV Pneumonia
BackgroundThe risk factors for mucus plug in children with adenovirus (ADV) pneumonia.
Methods and materialsA retrospective analysis was conducted...
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Mucus-Penetrating PEGylated Nanoshuttle for Enhanced Drug Delivery and Healthcare Applications
The delivery of therapeutic agents across mucosal barriers represents a significant challenge in drug delivery due to the protective nature of mucus...
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Modeling the effects of external oscillations on mucus clearance in obstructed airways
Various therapeutic methods are employed to facilitate the clearance of secretions accumulated in the respiratory tracts of individuals with lower...
