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Effects of depot medroxyprogesterone acetate, the copper IUD and the levonorgestrel implant on testosterone, sex hormone binding globulin and free testosterone levels: ancillary study of the ECHO randomized clinical trial
BackgroundRobust information on relative effects of hormonal contraceptives on endogenous androgens is important for understanding beneficial and...
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Impact of one-rod levonorgestrel implant on the blood chemistry profile
The aim of this study was to investigate the effect of a one-rod levonorgestrel implant on the blood chemistry profile, including random blood...
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Post-randomization Differences in Condomless Vaginal Sex Among Women Randomized to Intramuscular Depot Medroxyprogesterone Acetate Injections, a Copper Intrauterine Device or a Levonorgestrel Implant in the ECHO Trial
The Evidence for Contraceptive Options and HIV Outcomes (ECHO) trial found no substantial difference in HIV acquisition risk between women randomised...
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Simple and Novel Technique of Fixation for Levonorgestrel-Releasing Intrauterine Device for the Treatment of Uterine Adenomyosis
Levonorgestrel-releasing intrauterine device is widely used in the treatment of adenomyosis and heavy menstrual bleeding. For patients with large...
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Decision-making regarding immediate vs. interval postpartum levonorgestrel intrauterine device insertion timing
BackgroundUnderstanding decision-making for contraception initiation timing postpartum may help guide patients in selecting a contraceptive method...
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Long-term efficacy and safety of levonorgestrel releasing intrauterine system in the treatment of adenomyosis: evidence map**
PurposeTo summarize evidence on levonorgestrel releasing intrauterine system (LNG–IUS) in the treatment of adenomyosis (AM) and to identify potential...
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Acceptability of telemedicine for follow up after contraceptive implant initiation at an obstetrics and gynecologic training center
BackgroundDuring the COVID-19 pandemic, telemedicine has become a popular adjunct to in-person visits, including for family planning services. This...
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Comparison of levonorgestrel level and creamatocrit in milk following immediate versus delayed postpartum placement of the levonorgestrel IUD
BackgroundBreastfeeding and postpartum contraception critically influence infant and maternal health outcomes. In this pilot study, we explore the...
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Offering extended use of the contraceptive implant via an implementation science framework: a qualitative study of clinicians’ perceived barriers and facilitators
BackgroundThe etonogestrel contraceptive implant is currently approved by the United States Food and Drug Administration (FDA) for the prevention of...
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Models and methods to characterise levonorgestrel release from intradermally administered contraceptives
Microneedle (MN)-based technologies have been proposed as a means to facilitate minimally invasive sustained delivery of long-acting hormonal...
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Genital microbiota of women using a 90 day tenofovir or tenofovir and levonorgestrel intravaginal ring in a placebo controlled randomized safety trial in Kenya
In a phase-IIa trial, we investigated the influence of 90 days continuous-delivery tenofovir (TFV) intravaginal rings (IVRs) with/without...
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“I have come to remove it because of heavy bleeding”: a mixed-methods study on early contraceptive implant removal and the underlying factors in eastern Uganda
BackgroundEarly contraceptive implant removal without intentions to conceive predisposes women to unintended pregnancies.. Some of the unintended...
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Levonorgestrel Intrauterine System Insertion
The levonorgestrel-releasing intrauterine system (LNGIUS) is one of the most effective, safe, and convenient reversible contraceptive methods. The...
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Best Practices for Hormonal Contraception and Menopause Therapy in Women at Increased Risk for Breast Cancer
Purpose of ReviewThe present review critically assesses contemporary evidence characterizing the association between hormonal contraception (HC)...
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Postplacental Insertion of Levonorgestrel Intrauterine System Versus Copper Intrauterine Device: A Prospective Study
PurposeTo compare between postplacental insertion of levonorgestrel intrauterine system versus copper intrauterine device regarding expulsion rates,...
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Preparation, characterization, and in vivo evaluation of levonorgestrel-loaded thermostable microneedles
To facilitate the storage and use of poly (lactic-co-glycolic acid) (PLGA)-based microneedles (MNs) in hot seasons and regions, thermally stable MNs...
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Use of naproxen versus intracervical block for pain control during the 52-mg levonorgestrel-releasing intrauterine system insertion in young women: a multivariate analysis of a randomized controlled trial
BackgroundTo compare the effectiveness of 550 mg naproxen sodium versus 6 mL 2%-lidocaine intracervical block in pain lowering at the 52-mg...
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Ovarian stimulation for fertility preservation in an oncology patient with etonogestrel implant in place
PurposeTo describe a case of a young woman who presented for fertility preservation and underwent ovarian stimulation with an etonogestrel implant in...