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IcmF2 of the type VI secretion system 2 plays a role in biofilm formation of Vibrio parahaemolyticus
Vibrio parahaemolyticus possesses two distinct type VI secretion systems (T6SS), namely T6SS1 and T6SS2. T6SS1 is predominantly responsible for...
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Pseudomonas aeruginosa modulates alginate biosynthesis and type VI secretion system in two critically ill COVID-19 patients
BackgroundCOVID-19 pneumonia has caused huge impact on the health of infected patients and associated with high morbidity and mortality. Shift in the...
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A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing
Bacterial toxins represent a vast reservoir of biochemical diversity that can be repurposed for biomedical applications. Such proteins include a...
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Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community
Pseudomonas aeruginosa tends to be among the dominant species in multi-species bacterial consortia in diverse environments. To understand P....
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Seawater salt-trapped Pseudomonas aeruginosa survives for years and gets primed for salinity tolerance
BackgroundIn nature, microorganisms have to adapt to long-term stressful conditions often with growth limitations. However, little is known about the...
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CalR is required for the expression of T6SS2 and the adhesion of Vibrio parahaemolyticus to HeLa cells
Vibrio parahaemolyticus expresses one major virulence determinant T6SS2, which is constituted into three putative operons, i.e., VPA1027-1024,...
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Putative type VI secretion systems of Vibrio parahaemolyticus contribute to adhesion to cultured cell monolayers
Analysis of the genome sequence of Vibrio parahaemolyticus reveals two IcmF family genes in putative type VI secretion system (vpT6SS) clusters in...