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Isolation and Culture of Human Umbilical Vein Endothelial Cells (HUVECs)
This protocol describes a simple and an economical method for isolation of endothelial cells from human umbilical vein. Umbilical cord is easily...
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The effects of Quercetin on wound healing in the human umbilical vein endothelial cells
An injury that affects the integrity of the skin, either inside or externally, is called a wound. Damaged tissue is repaired by a set of cellular and...
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Human Umbilical Cord Mesenchymal Stem Cells Repair Endothelial Injury and Dysfunction by Regulating NLRP3 to Inhibit Endothelial Cell Pyroptosis in Kawasaki Disease
Vascular endothelial inflammation and endothelial dysfunction are the main causes of endothelial injury in Kawasaki disease (KD). Human umbilical...
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High glucose-induced injury in human umbilical vein endothelial cells is alleviated by vitamin D supplementation through downregulation of TIPE1
BackgroundDiabetes mellitus (DM) and its associated vascular complications have become a worldwide health concern. The effects and mechanism of...
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SICA-mediated cytoadhesion of Plasmodium knowlesi-infected red blood cells to human umbilical vein endothelial cells
Zoonotic malaria due to Plasmodium knowlesi infection in Southeast Asia is sometimes life-threatening. Post-mortem examination of human knowlesi ...
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Enhancement of endothelial function and attenuation of portal vein injury using mesenchymal stem cells carrying miRNA-25-3p
The aims of this study were to determine whether human umbilical cord mesenchymal stem cells (hucMSCs) modified by miRNA-25-3p (miR-25-3p)...
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Transformation of Human Umbilical Vein Endothelial Cells Induced by the Tumor Microenvironment of Nephroblastoma Cells
AbstractNephroblastoma is one of the most common renal malignancies in children, and tumor angiogenesis increases the risk of metastasis and...
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Exosomes from umbilical cord-derived mesenchymal stem cells combined with gelatin methacryloyl inhibit vein graft restenosis by enhancing endothelial functions
BackgroundThe prevalence of coronary artery disease is increasing. As a common treatment method, coronary artery bypass transplantation surgery can...
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Association of serum CTRP4 levels with vascular endothelial function in patients with type 2 diabetes mellitus: CTRP4 ameliorating inflammation, proliferation and migration in human umbilical vein endothelial cells
ObjectiveWe investigated the correlation between serum C1q/TNF-related protein 4 (CTRP4) level and flow-mediated dilation (FMD) in patients with type...
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Gene regulation for inflammation and inflammation resolution differs between umbilical arterial and venous endothelial cells
Systemic inflammation affects the whole vasculature, yet whether arterial and venous endothelial cells differ in their abilities to mediate...
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Hypoxia Affects Autophagy in Human Umbilical Vein Endothelial Cells via the IRE1 Unfolded Protein Response
ObjectiveThe purpose of this study was to investigate the role of the unfolded protein response, specifically the inositol-requiring enzyme 1 (IRE1)...
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Investigation of the optimal light parameters for photobiomodulation to induce osteogenic differentiation of the human bone marrow stem cell and human umbilical vein endothelial cell co-culture
Bones have an important role in the human body with their complex nature. Mesenchymal stem cells and endothelial cells together support their unique...
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Fingolimod does not prevent syndecan-4 shedding from the endothelial glycocalyx in a cultured human umbilical vein endothelial cell model of vascular injury
BackgroundShedding of the endothelial glycocalyx (EG) is associated with poor outcomes in a range of conditions including sepsis. Fresh frozen plasma...
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Grafted human-induced pluripotent stem cells-derived oligodendrocyte progenitor cells combined with human umbilical vein endothelial cells contribute to functional recovery following spinal cord injury
BackgroundSpinal cord injury (SCI) is a devastating disease that causes extensive damage to oligodendrocytes and neurons leading to demyelination and...
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Untargeted metabolomic analysis of ischemic injury in human umbilical vein endothelial cells reveals the involvement of arginine metabolism
ObjectiveIn this study, differentially expressed metabolites of vascular endothelial cells were examined to further understand the metabolic...
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The role of PPARγ in intermittent hypoxia-related human umbilical vein endothelial cell injury
PurposePatients with obstructive sleep apnoea (OSA) have a high incidence of vascular endothelial injury. The most important pathophysiological...
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miR-27a inhibits molecular adhesion between monocytes and human umbilical vein endothelial cells; systemic approach
ObjectiveThe endothelial cells overexpress the adhesion molecules in the leukocyte diapedesis pathway, develo** vessel subendothelial molecular...
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Isobavachalcone attenuates TNF-α-induced ICAM-1 and VCAM-1 expression in human umbilical vein endothelial cells by regulating the NF-κB signaling pathway
Vascular inflammation activated by pro-inflammatory cytokines is an inflammatory response that occurs in the early stages of atherosclerosis....
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Human placenta mesenchymal stem cell-derived exosome shuttling microRNA-130b-3p from gestational diabetes mellitus patients targets ICAM-1 and perturbs human umbilical vein endothelial cell angiogenesis
ObjectiveThe aim of this study was to investigate the roles of miR-130b-3p and ICAM-1 in gestational diabetes mellitus (GDM) and their potential...
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The effects of inhibition and siRNA knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formation
Blood vessels in the body are lined with endothelial cells which have vital roles in numerous physiological and pathological processes. Collagens are...
