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Determination of Solute Permeability of Microvascular Endothelial Cell Monolayers In Vitro
The microvascular endothelium has a critical role in regulating the delivery of oxygen, nutrients, and water to the surrounding tissues. Under...
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Schizophrenia endothelial cells exhibit higher permeability and altered angiogenesis patterns in patient-derived organoids
Schizophrenia (SCZ) is a complex neurodevelopmental disorder characterized by the manifestation of psychiatric symptoms in early adulthood. While...
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Capillary leak and endothelial permeability in critically ill patients: a current overview
Capillary leak syndrome (CLS) represents a phenotype of increased fluid extravasation, resulting in intravascular hypovolemia, extravascular edema...
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Endothelial Permeability and the Angiopoietin/Tie2 System Following Mild and Severe COVID-19
Endotheliopathy plays a role in the development of acute kidney and lung injury in COVID-19, probably due to inflammation, endothelial permeability,...
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Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease
BackgroundKawasaki disease (KD) is a pediatric systemic vasculitis characterized by endothelial cell dysfunction. Semaphorin 7A (Sema7A) has been...
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Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions
BackgroundHematopoietic stem cell transplantation involves irradiation preconditioning which causes bone marrow endothelial cell dysfunction. While...
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Amphetamine increases vascular permeability by modulating endothelial actin cytoskeleton and NO synthase via PAR-1 and VEGF-R
Abuse of amphetamine-type stimulants is linked to cardiovascular adverse effects like arrhythmias, accelerated atherosclerosis, acute coronary...
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Critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasis
AbstractAlthough mitogen-inducible gene 6 (MIG6) is highly expressed in vascular endothelial cells, it remains unknown whether MIG6 affects vascular...
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Interleukin-6 Downregulates the Expression of Vascular Endothelial-Cadherin and Increases Permeability in Renal Glomerular Endothelial Cells via the Trans-Signaling Pathway
The pathogenesis of IgA nephropathy (IgAN) is still unknown, but reportedly, interleukin 6 (IL-6) is involved in this process. However, its role in...
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The effects of resuscitation with different plasma products on endothelial permeability and organ injury in a rat pneumosepsis model
BackgroundEndothelial injury and permeability are a hallmark of sepsis. Initial resuscitation of septic patients with crystalloids is associated with...
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Activation of NMDA receptors in brain endothelial cells increases transcellular permeability
Neurovascular coupling is a precise mechanism that induces increased blood flow to activated brain regions, thereby providing oxygen and glucose. In...
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Heterogeneity of endothelial VE-PTP downstream polarization, Tie2 activation, junctional claudin-5, and permeability in the aorta and vena cava
Endothelial cells of mammalian blood vessels have multiple levels of heterogeneity along the vascular tree and among different organs. Further...
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An In Vitro Bilayer Model of Human Primary Retinal Pigment Epithelial and Choroid Endothelial Cells for Permeability Studies
The blood-retinal barrier (BRB) present in the posterior chamber of the eye plays a major role in maintaining the proper function and integrity of...
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Sinomenine alleviates glomerular endothelial permeability by activating the C/EBP-α/claudin-5 signaling pathway
Diabetic nephropathy (DN) is one of the main complications of diabetes. It is closely associated with the dysfunction of glomerular endothelial cells...
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6′-Sialylactose abolished lipopolysaccharide-induced inflammation and hyper-permeability in endothelial cells
Disruption of the endothelial barrier function and reduction in cell migration leads to endothelial dysfunction. One of the most abundant human milk...
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Geraniol attenuates oxygen-glucose deprivation/reoxygenation-induced ROS-dependent apoptosis and permeability of human brain microvascular endothelial cells by activating the Nrf-2/HO-1 pathway
Blood-brain barrier breakdown and ROS overproduction are important events during the progression of ischemic stroke aggravating brain damage....
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Measurement of Transendothelial Electrical Resistance in Blood-Brain Barrier Endothelial Cells
The integrity of the blood-brain barrier (BBB), the protective barrier of the brain, is key to maintaining normal microvascular permeability and...
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Brain Endothelial Cells Utilize Glycolysis for the Maintenance of the Transcellular Permeability
Among the components of the blood–brain barrier (BBB), endothelial cells (ECs) play an important role in supplying limited materials, especially...
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Mafosfamide, a cyclophosphamide analog, causes a proinflammatory response and increased permeability on endothelial cells in vitro
Post-transplantation cyclophosphamide (PTCy) has decreased GVHD incidence. Endothelial damage in allo-HCT is caused by multiple factors, including...
