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Gene therapy in a murine model of chronic eosinophilic leukemia-not otherwise specified (CEL-NOS)
Chronic eosinophilic leukemia-not otherwise specified (CEL-NOS) is a rare, aggressive, fatal disease characterized by blood eosinophilia and...
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T cell phenotype and lack of eosinophilia are not uncommon in extramedullary myeloid/lymphoid neoplasms with ETV6::FLT3 fusion: a case report and review of the literature
In the 2022, WHO and ICC classifications, myeloid/lymphoid neoplasms with eosinophilia (M/LN-eo) and tyrosine kinase gene fusions represent rare...
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Updates on eosinophilic disorders
This review addresses changes and updates in eosinophilic disorders under the International Consensus Classification (ICC). The previous category of...
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Comprehensive characterization of central BCL-2 family members in aberrant eosinophils and their impact on therapeutic strategies
PurposeHypereosinophilia represents a heterogenous group of severe medical conditions characterized by elevated numbers of eosinophil granulocytes in...
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Eosinophilic Disorders and Systemic Mastocytosis
Eosinophilic disorders are a group of rare and highly heterogenous diseases distinguished by increased eosinophil counts and may be associated with...
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Evolving Role of CAR T Cell Therapy in First- and Second-Line Treatment of Large B Cell Lymphoma
Purpose of ReviewWe review the recent practice-changing trials of anti-CD19 chimeric antigen receptor (CAR) T cell therapies in large B cell lymphoma...
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Clinicopathological differences in focal segmental glomerulosclerosis depending on the accompanying pathophysiological conditions in renal allografts
Primary focal segmental glomerulosclerosis (FSGS) is thought to be caused by circulating factors leading to podocytopathy, whereas segmental...
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Axicabtagene ciloleucel treatment is more effective in primary mediastinal large B-cell lymphomas than in diffuse large B-cell lymphomas: the Italian CART-SIE study
Axicabtagene ciloleucel showed efficacy for relapsed/refractory large B-cell lymphomas (LBCL), including primary mediastinal B-cell lymphomas...
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Efficacy and safety of bendamustine for lymphodepletion before lisocabtagene maraleucel
Bendamustine has been retrospectively shown to be an effective and safe lymphodepletion regimen prior to the anti-CD19 chimeric antigen receptor T...
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A Systematic Literature Review of Health-Related Quality of Life Outcomes and Associated Utility Values in Relapsed and/or Refractory Large B Cell Lymphoma
BackgroundIn this ever-expanding treatment landscape, there is a lack of consolidated health-related quality of life (HRQOL) outcomes and utility...
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CAR T-Cell Therapy
Chimeric antigen receptor (CAR) T-cell therapy is a cellular-based therapy that involves genetically engineering T cells to target specific antigen...
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Large B-Cell Lymphoma
The most recent WHO classification of tumors of hematopoietic and lymphoid tissues (Alaggio et al. 2022) classifies large B cell lymphomas (LBCL)...
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Thermal Analysis of the Influence of the Cast Iron Modification Parameters on the Solidification Parameters
AbstractThermal analysis (TA) of modified gray cast iron (GCI) and vermicular graphite cast iron (VGCI) treated by foreign and domestic graphitizing...
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Extremely strong coupling s-wave superconductivity in the medium-entropy alloy TiHfNbTa
Here we report a TiHfNbTa bulk medium-entropy alloy (MEA) superconductor crystallized in the body-centered cubic structure with the unit cell...
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T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapy
We report a T cell lymphoma (TCL) occurring 3 months after anti-CD19 chimeric antigen receptor (CAR) T cell immunotherapy for non-Hodgkin B cell...
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Beyond BCMA, why GPRC5D could be the right way: treatment strategies with immunotherapy at relapse after anti-BCMA agents
Multiple Myeloma remains incurable, and there is a need for therapies with novel mechanisms of action. Recently, B cell maturation antigen targeted...
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Bispecific antibodies and CAR-T cells: dueling immunotherapies for large B-cell lymphomas
Despite recent advances in frontline therapy for diffuse large B-cell lymphoma (DLBCL), at least a third of those diagnosed still will require second...
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International Consensus Classification of myeloid and lymphoid neoplasms: myeloproliferative neoplasms
The recently published International Consensus Classification (ICC) of myeloid neoplasms summarized the results of an in-depth effort by...
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The Formation Age of Pegmatites of the Mama Mica Belt: New U–Pb (ID-TIMS) Data on Zircons
AbstractNew geochronological (U–Pb ID-TIMS) data on zircons from pegmatites of the Mama mica belt in the Baikal Highlands are presented. The ages...
