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Antigen
An antigen is a molecule which, when introduced parenterally into the body, initiates the production of an antibody with which it reacts specifically...
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Das Antigen
Eine schlüssige Erklärung des Begriffes Antigen und seine Einordnung in die Transfusionsmedizin. Stellt zudem die verschiedenen Formen von Antigenen...
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Antigen–Antibody Reactions
The interactions between antigens and antibodies are known as antigen–antibody reactions. The reactions are highly specific, and an antigen reacts...
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Production and use of antigen tetramers to study antigen-specific B cells
B cells generate antibodies that provide protection from infection, but also cause pathology in autoimmune and allergic conditions. Antigen-specific...
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Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity
Ligand-induced receptor dimerization or oligomerization is a widespread mechanism for ensuring communication specificity, safeguarding receptor...
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Antigen-Antikörper-Reaktion
Die Grundlage der Transfusionsmedizin: Die Antigen-Antikörper-Reaktion und wie sie für die Diagnostik genutzt werden kann.
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Mammalian Antigen Display for Pandemic Countermeasures
Pandemic countermeasures require the rapid design of antigens for vaccines, profiling patient antibody responses, assessing antigen...
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Antigen-Presenting Cells and MHCs
In this chapter, we will discuss the principles of antigen presentation. We will learn that the major purpose of antigen-presenting cells, such as...
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Recreation of an antigen-driven germinal center in vitro by providing B cells with phagocytic antigen
Successful vaccines rely on activating a functional humoral immune response through the generation of class-switched high affinity immunoglobulins...
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Safety of applying influenza-antigen-coated microneedles to rat skin and the antigen specific immune response in vivo
PurposeTechnological advancements and innovations in the use of microneedles for medicinal purposes are constantly emerging. To promote the marketing...
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Vaccine design via antigen reorientation
A major challenge in creating universal influenza vaccines is to focus immune responses away from the immunodominant, variable head region of...
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Sequence-Based Nanobody-Antigen Binding Prediction
Nanobodies (Nb) are monomeric heavy-chain fragments derived from heavy-chain only antibodies naturally found in Camelids and Sharks. Their...
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Therapeutic potential of third-generation chimeric antigen receptor T cells targeting B cell maturation antigen for treating multiple myeloma
Multiple myeloma (MM) is an incurable hematologic malignancy characterized by the rapid proliferation of malignant plasma cells within the bone...
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Adaptive Immunity and Antigen Receptor Diversity
In this chapter, we will provide an overview on the roles of B and T cells in the response of the adaptive immune system to microbe invasion. In this...
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Role of Sialyl-Tn Antigen in Cancer Metastasis
Glycosylation is the most prominent posttranslational modification of proteins that regulates various protein functions and characteristics. Protein...
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CyTOF Intracellular Cytokine Assays for Antigen-Specific T Cells
T cells specific for a single antigen tend to be rare, even after expansion of memory cells. They are commonly detected by in vitro stimulation with...
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Novel tumor marker index using carcinoembryonic antigen and carbohydrate antigen 19-9 is a significant prognostic factor for resectable colorectal cancer
We evaluated the usefulness of a newly devised tumor marker index (TMI), namely, the geometric mean of normalized carcinoembryonic antigen (CEA) and...
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H. pylori Stool Antigen Test
Helicobacter pylori (H. pylori) stool antigen (HpSA) test is a reliable noninvasive diagnostic method for the detection of H. pylori infection in...
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Information-Driven Antibody–Antigen Modelling with HADDOCK
In the recent years, therapeutic use of antibodies has seen a huge growth, "due to their inherent proprieties and technological advances in the...