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Anticoagulants and Their Reversal
Anticoagulants are used in the management of thromboembolism and preventing thrombotic complications in patients with cardiac comorbidities such as...
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Anticoagulants Antiplatelets and Antifibrinolytics
Coagulopathy refers to an abnormal state of hemostasis. The incidence of coagulopathy in neurocritical care is described variedly between 14 and 80%...
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Anticoagulants
Anticoagulants and antithrombotic drugs are among the most frequently prescribed drugs. In the last 20 years, new drug classes have emerged, which...
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Production and Testing of RNA Origami Anticoagulants
Nucleic acid nanotechnology provides the ability to create unprecedented nanostructures with diverse architectures and functions that can be utilized...
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Anticoagulants in Trauma
This is a chapter to familiarise the reader on the latest anticoagulants and reversal strategies in trauma (or any medical haemorrhagic) situations....
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Reversal and resumption of anticoagulants in patients with anticoagulant-associated intracerebral hemorrhage
The use of anticoagulants has become more frequent due to the progressive aging population and increased thromboembolic events. Consequently, the...
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Anticoagulants and Thrombolytics
Patients with end-stage kidney disease have underlying platelet dysfunction and often receive anti-platelet and anticoagulant medications for various...
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Anticoagulants in adult extracorporeal membrane oxygenation: alternatives to standardized anticoagulation with unfractionated heparin
BackgroundExtracorporeal membrane oxygenation (ECMO) is a vital technique for severe respiratory or heart failure patients. Bleeding and thrombotic...
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Anticoagulants in Use
Anticoagulation plays a critical role in the management of neurologic disorders. Selection of an anticoagulant must consider both drug-specific and...
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Direct oral anticoagulants for oral anticoagulants-naïve Asian patients with atrial fibrillation and end-stage renal disease undergoing dialysis
In Asian patients with atrial fibrillation (AF) and end-stage renal disease (ESRD) undergoing dialysis, the use of direct oral anticoagulants (DOACs)...
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Acute Nonvariceal Upper Gastrointestinal Bleeding in Patients Using Anticoagulants: Does the Timing of Endoscopy Affect Outcomes?
BackgroundIn patients with acute nonvariceal upper gastrointestinal bleeding (NVUGIB), early (≤ 24 h) endoscopy is recommended following hemodynamic...
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Development of supramolecular anticoagulants with on-demand reversibility
Drugs are administered at a dosing schedule set by their therapeutic index, and termination of action is achieved by clearance and metabolism of the...
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Anticoagulants and Antiplatelet Agents in Cirrhosis
Anticoagulants and antiplatelet agents are increasingly used to treat or prevent thromboembolic conditions in patients with cirrhosis. In this...
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Reply: Comparison of Two Anticoagulants for Pain Associated with Platelet-Rich Plasma Injections
We read the letter titled "Comparison of Two Anticoagulants for Pain Associated with Platelet-Rich Plasma Injections" authored by Pensato et al. in...
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Efficacy and Safety of Direct Oral Anticoagulants in Pediatric Venous Thromboembolism: A Systematic Review and Meta-Analysis
ObjectivesTo assess the efficacy and safety of direct oral anticoagulants (DOACs) in comparison to standard-of-care (SOC) anticoagulants in the...
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Risk of post-operative bleeding after dentoalveolar surgery in patients taking anticoagulants: a cohort study using the common data model
This retrospective study aimed to determine risk factors associated with post-operative bleeding after dentoalveolar surgery in patients taking...
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Direct Oral Anticoagulants for Cancer-Associated Venous Thromboembolism
Purpose of ReviewTo present the randomized controlled trial (RCT) evidence and highlight the areas of uncertainty regarding direct oral...
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Evaluation and treatment of gastrointestinal bleeding in patients taking anticoagulants presenting to the emergency department
This manuscript is a consensus document of an expert panel on the Evaluation and Treatment of Gastrointestinal Bleeding in Patients Taking...