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The Actin Cytoskeleton in Pollen Tubes; Actin and Actin Binding Proteins
Actin cytoskeleton is well known to be a key element for the germination and the elongation of pollen tubes. It has been appreciated that the... -
Ciliary tip actin dynamics regulate photoreceptor outer segment integrity
As signalling organelles, cilia regulate their G protein-coupled receptor content by ectocytosis, a process requiring localised actin dynamics to...
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Biochemical and mechanical regulation of actin dynamics
Polymerization of actin filaments against membranes produces force for numerous cellular processes, such as migration, morphogenesis, endocytosis,...
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Studying Nuclear Dynamics in Response to Actin Disruption in Planta
The plant nucleus and the actin cytoskeleton are intimately connected. The actin cytoskeleton is pivotal for nuclear positioning, shape, and... -
Visualization and Quantification of the Dynamics of Actin Filaments in Arabidopsis Pollen Tubes
The actin cytoskeleton plays an essential role in the regulation of polarized pollen tube growth, and its functions are dictated by its spatial... -
AtHMGB15 regulates tapetal apoptosis in pollen development and actin dynamics during pollen germination in arabidopsis
Key messageARID-HMG DNA binding protein, AtHMGB15, regulates pollen development and pollen germination in Arabidopsis .
AbstractPrevious studies have...
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Loss of SIL1 Affects Actin Dynamics and Leads to Abnormal Neural Migration
SIL1 is a nucleotide exchange factor for the molecular chaperone protein Bip in the endoplasmic reticulum that plays a crucial role in protein...
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NET1 is a critical regulator of spindle assembly and actin dynamics in mouse oocytes
BackgroundNeuroepithelial transforming gene 1 (NET1) is a RhoA subfamily guanine nucleotide exchange factor that governs a wide array of biological...
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Imaging and Analysis of the Dynamics of Filamentous Actin Structures in Live Endothelial Cells
The ability to view and record the movements of subcellular structures is a powerful tool that has accelerated the discovery and understanding of... -
Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament
Regulation of the assembly and turnover of branched actin filament networks nucleated by the Arp2/3 complex is essential during many cellular...
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GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis
The serine/threonine kinase, PINK1, and the E3 ubiquitin ligase, Parkin, are known to facilitate LC3-dependent autophagosomal encasement and...
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Nuclear Actin Dynamics in Gene Expression, DNA Repair, and Cancer
Actin is a highly conserved protein in mammals. The actin dynamics is regulated by actin-binding proteins and actin-related proteins. Nuclear actin... -
BioID Analysis of Actin-Binding Proteins
Proteins often exist and function as part of higher-order complexes or networks. A challenge is to identify the universe of proximal and interacting... -
Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite
Actin polymerization generates forces for cellular processes throughout the eukaryotic kingdom, but our understanding of the ‘ancient’ actin turnover...
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Emerging roles of deubiquitinating enzymes in actin cytoskeleton and tumor metastasis
BackgroundMetastasis accounts for the majority of cancer-related deaths. Actin dynamics and actin-based cell migration and invasion are important...
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Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin
Microtubule-associated protein 1a (Map1a) is a microtubule (MT) regulatory protein that binds to the MT protofilaments in mammalian cells to promote...
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ERRα coordinates actin and focal adhesion dynamics
Cell migration depends on the dynamic organisation of the actin cytoskeleton and assembly and disassembly of focal adhesions (FAs). However, the...
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Ribosomal Protein Dynamics and Its Association with Actin Filaments and Local Translation in Axonal Growth Cones of Dorsal Root Ganglia Neurons
Local translation in growth cones plays a critical role in responses to extracellular stimuli, such as axon guidance cues. We previously showed that...
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Quantitative structured illumination microscopy via a physical model-based background filtering algorithm reveals actin dynamics
Despite the prevalence of superresolution (SR) microscopy, quantitative live-cell SR imaging that maintains the completeness of delicate structures...
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Focal adhesions contain three specialized actin nanoscale layers
Focal adhesions (FAs) connect inner workings of cell to the extracellular matrix to control cell adhesion, migration and mechanosensing. Previous...