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The combination of machine learning and untargeted metabolomics identifies the lipid metabolism -related gene CH25H as a potential biomarker in asthma
BackgroundLipids, significant signaling molecules, regulate a multitude of cellular responses and biological pathways in asthma which are closely...
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Black Seed (Nigella sativa): A Favourable Alternative Therapy for Inflammatory and Immune System Disorders
In the recent years, various food additives, medicinal plants, and their bioactive components have been utilized in anti-inflammatory and...
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Association between psoriasis and asthma: a systematic review and bidirectional meta-analysis
BackgroundThe risk of asthma in patients with psoriasis has been identified in previous studies, but the bidirectional association between the two...
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Update on the association between Helicobacter pylori infection and asthma in terms of microbiota and immunity
H. pylori is a gram-negative bacterium that is usually acquired in childhood and can persistently colonize the gastric mucosa of humans, affecting...
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General Anesthetics
The existing general anesthetic agents were developed gradually after the discovery of nitrous oxide, ether, and chloroform in the 1880s. The search... -
Microbiome in Asthma-COPD Overlap (ACO)
Microbiome plays a pivotal role in maintaining host physiological homeostasis through degenerating toxicants, resisting pathogens, absorbing... -
Assessment of the Phytochemical Constituents and Metabolites in the Medicinal Plants and Herbal Medicine Used in the Treatment and Management of Respiratory Diseases
Worldwide, chronic obstructive pulmonary disease, asthma, lung cancer, and cystic fibrosis are some of the top causes of death and morbidity. As a... -
Antiallergic Implications of Curcumin During COVID-19: Current Status and Perspectives
COVID-19 has impacted almost all nooks and corners of the globe. Initially, it was thought to cause respiratory ailments. However, the virions have... -
Potential role of lipoxin in the management of COVID-19: a narrative review
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection leads to the development of coronavirus disease 2019 (COVID-19), which causes...
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Antioxidants and Immunomodulation
The immune system, one of the most sophisticated defence systems of the body, is capable of recognizing and eliminating the unlimited varieties of... -
Repurposing Marketed Drugs as Antidepressants with In Silico, In Vivo, and In Vitro Screening Methods
Drug repurposing is a strategy to identify new therapeutic uses for marketed drugs, discontinued or shelved drugs, and drug candidates in clinical... -
Vitamin B6 regulates IL-33 homeostasis to alleviate type 2 inflammation
Interleukin-33 (IL-33) is a crucial nuclear cytokine that induces the type 2 immune response and maintains immune homeostasis. The fine-tuned...
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Trained immunity in type 2 immune responses
Immunological memory of innate immune cells, also termed “trained immunity”, allows for cross-protection against distinct pathogens, but may also...
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The promising antioxidant effects of lignans: Nrf2 activation comes into view
Lignans are biologically active compounds widely distributed, recognized, and identified in seeds, fruits, and vegetables. Lignans have several...
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Basic Pharmacology for Anaesthesia Providers
Most drugs can be stored at ambient temperature. Inhalational anaesthetics, muscle relaxant drugs, and oxytocin are exceptions and need storage in a... -
Tannic acid assisted anti-TNF-α nanobody assembly modulating the epithelial barrier dysregulation of allergic rhinitis
The derailed nasal epithelial barrier is associated with the disorder of tight junctions (TJ) function or expression, leading to more penetration of...
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Plant-Based Chemical Moieties for Targeting Chronic Respiratory Diseases
The World Health Organization (WHO) has reported that chronic respiratory diseases such as asthma, chronic obstructive pulmonary disease,... -
Holy Basil (Ocimum sanctum L.): An Important Indian Medicinal and Aromatic Plant: Its Properties, Utilization and Genetic Improvement
Holy Basil or Tulsi (Ocimum sanctum L.) is one of the most sacred plants and is under cultivation, in India, for more than 3000 years. It’s medicinal... -
Sugarcane Juice Powder Produced from Spray Drying Technology: A Review of Properties and Operating Parameters
Sugarcane juice (SGJ) has been known to possess nutritious, curative, and preventive properties. However, its use and marketing have been greatly...
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Cough and Allergic Diseases
Cough is an explosive expiratory maneuver that is reflexively or deliberately intended to clear the airways. It is one of the most common symptoms...