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Frailty and Mobility Degeneration in Diabetes and Diabetic Foot Ulceration
Diabetes in aging communities imposes a substantial personal and public health burden by virtue of its high prevalence, its capacity to cause...
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Frailty Assessed by the Clinical Frailty Scale is Associated with Prognosis After Esophagectomy
BackgroundThe Clinical Frailty Scale (CFS) is a simple and validated tool for assessing frailty, and higher CFS scores are correlated with worse...
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Association between co-exposure to phenols, phthalates, and polycyclic aromatic hydrocarbons with the risk of frailty
The phenomenon of population aging has brought forth the challenge of frailty. Nevertheless, the contribution of environmental exposure to frailty...
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Nocturia and frailty in older adults: a sco** review
BackgroundMore than one in two older people wake up several times a night to urinate. Far from being a minor inconvenience, nocturia is associated...
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Association between Frailty Assessed Using Two Electronic Medical Record-Based Frailty Assessment Tools and Long-Term Adverse Prognosis in Older Critically Ill Survivors
ObjectivesFrailty has become an independent risk factor for adverse outcomes in critically ill patients. This study aimed to explore the predictive...
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Lower serum creatinine to cystatin C ratio associated with increased incidence of frailty in community-dwelling elderly men but not in elderly women
BackgroundSarcopenia has been reported to play an important role in frailty syndrome. The serum creatinine/serum cystatin C ratio (Scr/Cys C ratio)...
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What role do extracellular vesicles play in develo** physical frailty and sarcopenia?
BackgroundFrailty and sarcopenia are typical geriatric conditions with a complex pathophysiology. Extracellular vesicles (EVs) are key regulators of...
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The association of low serum magnesium levels with frailty among hemodialysis patients
Frailty is common among hemodialysis patients and is associated with mortality and fractures. Hypomagnesemia is also known to be a risk factor for...
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Exploring the metabolomics profile of frailty- a systematic review
BackgroundFrailty is a multifaceted geriatric syndrome characterized by an increased vulnerability to stressful events. metabolomics studies are...
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Mitochondrial Alterations and Signaling in Aging, Frailty, and Sarcopenia: An Integrated View
Aging, a highly complex and multifactorial process, can be framed as a physiological mismatch resulting from decreasing resilience and increasing...
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Cellular senescence and frailty: a comprehensive insight into the causal links
Senescent cells may have a prominent role in driving inflammation and frailty. The impact of cellular senescence on frailty varies depending on the...
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Emerging Evidence on the Use of Probiotics and Prebiotics to Improve the Gut Microbiota of Older Adults with Frailty Syndrome: A Narrative Review
BackgroundThe gut microbiota can impact older adults’ health, especially in patients with frailty syndrome. Understanding the association between the...
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Frailty is not an independent risk factor for worse clinical outcomes in lumbar spinal surgery: a prospective cohort study
PurposeRecently, many studies revealed that frailty affects unfavorably on postoperative outcomes in lumbar spinal diseases. This study aimed to...
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Aging and putative frailty biomarkers are altered by spaceflight
Human space exploration poses inherent risks to astronauts’ health, leading to molecular changes that can significantly impact their well-being....
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Frailty and Oral Health
As the worldwide population ages, a challenge for oral health-care professionals is how to assess and manage oral conditions in older adults. During...
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Frailty in Chile: Development of a Frailty Index Score Using the Chilean National Health Survey 2016–2017
BackgroundThe Frailty Index (FI) is used to quantify and summarize vulnerability status in people. In Chile, no development and assessment of a FI...
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Symptomatic and preventive medication use according to age and frailty in Australian and Japanese nursing homes
ObjectiveTo investigate symptomatic and preventive medication use according to age and frailty in Australian and Japanese nursing homes (NHs).
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Falls, fracture and frailty risk in multiple sclerosis: a Mendelian Randomization study to identify shared genetics
IntroductionPatients with multiple sclerosis (MS) commonly present musculoskeletal disorders characterized by lower bone mineral density (BMD) and...
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The role of frailty in the relationships between social relationships and health outcomes: a longitudinal study
BackgroundSocially isolated older adults incur increased risks of adverse health outcomes, though the strength of this association is unclear. We...
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Transitions of self-management behaviors and frailty status among community-dwelling older adults: a national longitudinal population-based cohort study
BackgroundFrailty in older adults is a common geriatric syndrome that could be prevented; thus, co** strategies for the aging population are...
