Search

Search Results

1. Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions

   Naturally generated lipid nanoparticles termed extracellular vesicles (EVs) hold significant promise as engineerable therapeutic delivery vehicles....

   Justin A. Peruzzi, Taylor F. Gunnels, ... Neha P. Kamat in Nature Communications

   Article Open access 04 July 2024
   

2. Chitosan-based Hydrogels in Drug Delivery

   Hydrogels are three-dimensional cross-linked hydrophilic polymers that are able to absorb large quantities of water and swell. They have various...

   Salma A. Fereig, Mona M. A. Abdel-Mottaleb in Biomaterial-based Hydrogels

   Chapter 2024
   

3. Recent advances in gene delivery nanoplatforms based on spherical nucleic acids

   Gene therapy is a therapeutic option for mitigating diseases that do not respond well to pharmacological therapy. This type of therapy allows for...

   Nazila Valatabar, Fatemeh Oroojalian, ... Amirhossein Sahebkar in Journal of Nanobiotechnology

   Article Open access 01 July 2024
   

4. Electroactive nanoinjection platform for intracellular delivery and gene silencing

   Background

   Nanoinjection—the process of intracellular delivery using vertically configured nanostructures—is a physical route that efficiently...

   Ali-Reza Shokouhi, Ya** Chen, ... Roey Elnathan in Journal of Nanobiotechnology

   Article Open access 17 August 2023
   

5. Recent progress of iron-based nanomaterials in gene delivery and tumor gene therapy

   Gene therapy aims to modify or manipulate gene expression and change the biological characteristics of living cells to achieve the purpose of...

   Ya Gong, **aoyan Hu, ... Jun Wang in Journal of Nanobiotechnology

   Article Open access 02 June 2024
   

6. Multi-step screening of DNA/lipid nanoparticles and co-delivery with siRNA to enhance and prolong gene expression

   Lipid nanoparticles hold great potential as an effective non-viral vector for nucleic acid-based gene therapy. Plasmid DNA delivery can result in...

   Yining Zhu, Ruochen Shen, ... Hai-Quan Mao in Nature Communications

   Article Open access 25 July 2022
   

7. Convenient synthesis and delivery of a megabase-scale designer accessory chromosome empower biosynthetic capacity

   Synthetic biology confers new functions to hosts by introducing exogenous genetic elements, yet rebuilding complex traits that are based on...

   Yuan Ma, Shuxin Su, ... Ying-** Yuan in Cell Research

   Article Open access 08 February 2024
   

8. Precision drug delivery to the central nervous system using engineered nanoparticles

   Development of novel therapies for central nervous system (CNS) disorders has experienced a high failure rate in clinical trials owing to...

   **g**g Gao, Ziting (Judy) **a, ... Nitin Joshi in Nature Reviews Materials

   Article 25 June 2024
   

9. Targeted gene delivery systems for T-cell engineering

   T lymphocytes are indispensable for the host systems of defense against pathogens, tumors, and environmental threats. The therapeutic potential of...

   Fengling Wang, Yong Huang, ... Wei Wang in Cellular Oncology

   Article 16 May 2024
   

10. BSA-PEI Nanoparticle Mediated Efficient Delivery of CRISPR/Cas9 into MDA-MB-231 Cells

    The discovery of bacterial-derived Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system has...

    Hossein Rahimi, Kasra Arbabi Zaboli, ... Saeed Kaboli in Molecular Biotechnology

    Article 07 June 2022
    

11. A novel intradermal tattoo-based injection device enhances the immunogenicity of plasmid DNA vaccines

    In recent years, tattooing technology has shown promising results toward evaluating vaccines in both animal models and humans. However, this...

    Alejandro M. Gomez, George (Giorgi) Babuadze, ... Gary P. Kobinger in npj Vaccines

    Article Open access 22 December 2022
    

12. Efficient delivery of a large-size Cas9-EGFP vector in porcine fetal fibroblasts using a Lonza 4D-Nucleofector system

    Background

    Porcine fetal fibroblasts (PFFs) are important donor cells for generating genetically modified pigs, but the transfection efficiencies of...

    Weiwei Liu, **aoguo Wang, ... Yuyun **ng in BMC Biotechnology

    Article Open access 16 August 2023
    

13. Selective attachment of a microtubule interacting peptide to plasmid DNA via a triplex forming oligonucleotide for transfection improvement

    In nonviral gene therapy approaches, the linkage of signal molecules to plasmid DNA (pDNA) is of interest for guiding its delivery to the nucleus....

    Caroline Girardin, Delphine Maze, ... Patrick Midoux in Gene Therapy

    Article 07 July 2022
    

14. Combining Ultrasound-Mediated Intracellular Delivery with Microfluidics in Various Applications

    Ultrasound-mediated intracellular delivery is one of the popular technologies based on membrane rupture at present. To date, ultrasound directly acts...

    Guangyong Huang, Lin Lin, ... Hui You in BioChip Journal

    Article 28 November 2023
    

15. Carbon-based nanomaterials for CRISPR/Cas delivery: a perspective on the design approach

    This perspective article delves into the evolving landscape of non-viral vectors for efficient CRISPR delivery, addressing the challenges associated...

    Moein Safarkhani, Mohammad Reza Saeb, ... Navid Rabiee in Carbon Letters

    Article 26 December 2023
    

16. Hydrogels for RNA delivery

    RNA-based therapeutics have shown tremendous promise in disease intervention at the genetic level, and some have been approved for clinical use,...

    Ruibo Zhong, Sepehr Talebian, ... **jun Shi in Nature Materials

    Article 20 March 2023
    

17. Synergistic vesicle-vector systems for targeted delivery

    With the immense progress in drug delivery systems (DDS) and the rise of nanotechnology, challenges such as target specificity remain. The...

    Christine Ardelle Marquez, Cho-Im Oh, ... Ji-Young Ahn in Journal of Nanobiotechnology

    Article Open access 03 January 2024
    

18. Coupling of nanostraws with diverse physicochemical perforation strategies for intracellular DNA delivery

    Effective intracellular DNA transfection is imperative for cell-based therapy and gene therapy. Conventional gene transfection methods, including...

    Juan Jiang, **g Liu, ... ** **e in Journal of Nanobiotechnology

    Article Open access 26 March 2024
    

19. Exosomes for CRISPR-Cas9 Delivery: The Cutting Edge in Genome Editing

    Gene mutation correction was challenging until the discovery of clustered regularly interspaced short palindromic repeats (CRISPR) and...

    Cynthia Aslan, Naime Majidi Zolbanin, ... Reza Jafari in Molecular Biotechnology

    Article 27 November 2023
    

20. Application of Nanofillers in Drug Delivery Industry

    Nanofillers are a type of drug delivery system that utilizes nanoparticles as a method of transporting medications to specific regions within the...

    Asma Almontasser, Salah M. S. Al-Mufti, Raj Kumar Arya in Handbook of Nanofillers

    Living reference work entry 2024