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Classification of the present pharmaceutical agents based on the possible effective mechanism on the COVID-19 infection
ObjectivesThere are several types of research on the COVID-19 disease which have been conducting. It seems that prevailing over the pandemic would be...
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Aerosolized Antifungals for the Treatment of Pulmonary Fungal Diseases
Purpose of ReviewInhaled antifungals achieve high lung concentrations with minimal systemic adverse events. Despite being available for over five...
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Moringa oleifera Accessions: Perspectives and Application as Nutraceuticals and Phytomedicines
Plants and plant-based products are considered as natural source of bioactives, which are essential elements in advancement of phytomedicines.... -
Micrococcus luteus-derived extracellular vesicles attenuate neutrophilic asthma by regulating miRNAs in airway epithelial cells
Bacterial extracellular vesicles (EVs) have been shown to regulate various pulmonary diseases, but their functions in asthma remain uncertain. To...
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Asthma and Anaphylaxis—interconnected entities
Purpose of reviewThe relationship between asthma and anaphylaxis is not completely defined, and it is necessary to establish their association and...
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Iristectorigenin A: Advances on Its Resources, Biological Activities, Molecular Mechanisms of Action, and Future Perspectives
Iristectorigenin A is a polyphenol existing primarily in rhizomes and leaves of various plant family species but mainly has been reported in... -
Asthma
Asthma is characterized by inflammation of the conducting airways. It is a heterogeneous disease in terms of immunological, physiopathological,... -
Immunomodulatory effects of modified Liu-Wei-Di-Huang-Wan Traditional Chinese medicine on allergic asthmatic mice
BackgroundAllergic asthma occurs worldwide and is particularly prevalent in westernized countries characterized by chronic airway inflammation...
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Therapeutic Potential of Resveratrol and Lignans in the Management of Tuberculosis
This study aims to investigate the therapeutic potential of herbal remedies, specifically resveratrol and lignans, as alternative treatments for...
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Cannabinoids as Promising Anti-inflammatory Agent
Inflammation is a reaction of immune system to external stress conditions or any microbial attack on body, or it may be followed by autoimmune... -
Mechanistic and Therapeutic Approaches to Occupational Exposure-Associated Allergic and Non-Allergic Asthmatic Disease
Purpose of ReviewOccupational lung disease, including asthma, is a significant cause of disability worldwide. The dose, exposure frequency, and...
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Inhaled Adjunct Therapy with Second-Line Drug Candidates for Dose Reduction in Chemotherapeutic Regimens for Multi-drug-Resistant Tuberculosis
Chemotherapy of multi-drug-resistant tuberculosis (TB) requires prolonged administration of multiple drugs. We investigated whether pulmonary...
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Nanoparticles Solutions for Allergic Airway Disorders: Current Trends and Future Prospects
The present work explores the world of nanoparticles as a potential solution, for addressing allergic airway diseases. The ailments, such as asthma... -
Wnt5a-mediated autophagy contributes to the epithelial-mesenchymal transition of human bronchial epithelial cells during asthma
BackgroundThe epithelial-mesenchymal transition (EMT) of human bronchial epithelial cells (HBECs) is essential for airway remodeling during asthma....
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Medicinal and Therapeutic Properties of Ephedra
Ephedra is one of the oldest medicinal plants in traditional Chinese medicine for nearly 5000 years. The medicinal species are used as a stimulant...
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An integrated metabo-lipidomics profile of induced sputum for the identification of novel biomarkers in the differential diagnosis of asthma and COPD
BackgroundDue to their complexity and to the presence of common clinical features, differentiation between asthma and chronic obstructive pulmonary...
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Newer Biological Agents in the Treatment of Severe Asthma: Real-World Results from a Tertiary Referral Center
PurposeTo determine the efficacy of IL-5 inhibitory therapy in severe, refractory asthma in a real-world clinical setting from a tertiary referral...
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Diagnostic and therapeutic value of EVs in lungs diseases and inflammation
Extracellular vesicles (EVs) are membrane-derived messengers which have been playing an important role in the inflammation and pathogenesis of lung...
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Natural Products for the Management of Asthma and COPD
Chronic airway inflammatory diseases like asthma, chronic obstructive pulmonary disease (COPD), and their associated exacerbations cause significant... -
Roles of sirtuins in asthma
Sirtuins are nicotinamide adenine dinucleotide (NAD + )-dependent lysine deacylases and deacetylases that participate in a variety of cellular...