Search
Search Results
-
Multivalent next generation influenza virus vaccines protect against seasonal and pre-pandemic viruses
Each year, new influenza virus vaccine formulations are generated to keep up with continuously circulating and mutating viral variants. A...
-
AS03-adjuvanted H7N9 inactivated split virion vaccines induce cross-reactive and protective responses in ferrets
Human infections with avian H7N9 subtype influenza viruses are a major public health concern and vaccines against H7N9 are urgently needed for...
-
Molecular characterization of influenza virus circulating in Nepal in the year 2019
Influenza (sometimes referred to as “flu”) is a contagious viral infection of the airways in the lungs that affects a significant portion of the...
-
The effect of single amino acid substitution at position 220 in the hemagglutinin glycoprotein on avian influenza H7N9 candidate vaccine virus
Influenza vaccines represent the most effective preventive strategy to control influenza virus infections; however, adaptive mutations frequently...
-
Monoclonal antibody targeting a novel linear epitope on nucleoprotein confers pan-reactivity to influenza A virus
AbstractNucleoprotein (NP) functions crucially in the replicative cycle of influenza A virus (IAV) via forming the ribonucleoprotein complex together...
-
Detecting zoonotic Influenza A using QIAstat-Dx Respiratory SARS-CoV-2 panel for pandemic preparedness
Recent reports from the World Health Organization regarding Influenza A cases of zoonotic origin in humans (H1v and H9N2) and publications describing...
-
Need for standardization of Influenza A virus-induced cell death in vivo to improve consistency of inter-laboratory research findings
The involvement of necroptosis in the control of influenza A virus (IAV) infection has been reported in multiple studies. Downstream of the nucleic...
-
Optical transmission for precise discrimination of influenza A virus subtypes: a comprehensive study on light interaction and collimated transmittance
Optical transmission is a widely used technique that uses the interaction of light and viral molecules to identify viruses in a variety of materials....
-
Influenza Virus Entry inhibitors
Influenza is a major challenge to health and the global economy. However, the increasing emergence of drug resistance during influenza pandemics...
-
Paper-based electrochemical immunosensor for label-free detection of multiple avian influenza virus antigens using flexible screen-printed carbon nanotube-polydimethylsiloxane electrodes
Many studies have been conducted on measuring avian influenza viruses and their hemagglutinin (HA) antigens via electrochemical principles; most of...
-
VLPs containing stalk domain and ectodomain of matrix protein 2 of influenza induce protection in mice
BackgroundAs a result of antigenic drift, current influenza vaccines provide limited protection against circulating influenza viruses, and vaccines...
-
“Lights out” poultry production and pandemic influenza
Poultry production makes a substantial contribution to global food security, providing energy, protein, and essential micro-nutrients to humans....
-
Influenza from a One Health Perspective: Infection by a Highly Versatile Virus
Influenza A viruses (IAVs) are among the most versatile viruses, in terms of host range, pathogenesis, route of transmission, transmissibility...
-
The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome
The current model is that the influenza virus polymerase (FluPol) binds either to host RNA polymerase II (RNAP II) or to the acidic nuclear...
-
Spatial and temporal clusters of avian influenza a (H7N9) virus in humans across five epidemics in mainland China: an epidemiological study of laboratory-confirmed cases
BackgroundAvian influenza A (H7N9) virus was first reported in mainland China in 2013, and alarming in 2016–17 due to the surge across a wide...
-
Influenza antibody breadth and effector functions are immune correlates from acquisition of pandemic infection of children
Cross-reactive antibodies with Fc receptor (FcR) effector functions may mitigate pandemic virus impact in the absence of neutralizing antibodies. In...
-
Progress on Epidemiology of Influenza A(H1N1)
Pandemic influenza A(H1N1) in 2009 is an acute respiratory infectious disease caused by the mutated novel influenza A(H1N1) virus. Patients usually...
-
RDN for the treatment of influenza in children: a randomized, double-blinded, parallel-controlled clinical trial
BackgroundThe morbidity of influenza in children increased rapidly in decade. Reduning injection (RDN), a small but fine Chinese herbal formula, has...
-
Co-evolution of immunity and seasonal influenza viruses
Seasonal influenza viruses cause recurring global epidemics by continually evolving to escape host immunity. The viral constraints and host immune...
-
Influenza Vaccine: An Engineering Vision from Virological Importance to Production
According to data from the World Health Organization (WHO) every year, millions of people are affected by flu. Flu is a disease caused by influenza...