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La propolis : origine, composition et propriétés
Propolis is a resinous substance gathered by honeybees ( Apis mellifera ) which biochemical composition depends on botanical sources. This review gives...
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Composés bioactifs des Crucifères : un apport bénéfique dans notre quotidien
Crucifers, i.e. Brassicaceae, constitute a large family of plants — mustard, cabbage, radish, turnip, cress, rocket, wasabi, oilseed rape, etc. —...
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Cellules souches du cancer du sein : prendre le cancer à la racine
In cancer stem cell (CSC) hypothesis, tumors are organized in a hierarchical model with CSC at the top of the hierarchy. CSCs display both stem cell...
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Inhibiteurs de tyrosine-kinase de 2e génération et associations: perspectives
Second-generation tyrosine-kinase inhibitors enable an earlier and higher quality molecular response to be achieved than with imatinib in patients...
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Les thérapies ciblées de l’os métastatique: soins de support ou traitements de fond ?
Bone metastases in prostate cancer treatment stand as a clinical challenge in order to maintain quality of life and prevent pain and skeletal-related...
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Activités antioxydante, apoptotique et antiproliférative de Tetraena gaetula (Emb. & Maire) Beier & Thulin et de Berberis hispanica Boiss. & Reut. originaires du Maroc
The aqueous extracts (AE) of aerial part of Tetraena gaetula and root bark of Berberis hispanica showed some interesting immunomodulatory activities...
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Effets antiangiogéniques dans le traitement des hémopathies malignes
Angiogenesis is recognised as amajor factor in the development of solid tumours and it is only recently that similar mechanisms have been described...
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Thérapies ciblées dans le traitement des carcinomes de l’ovaire
Despite the improvement in surgical management for ovarian carcinoma, it remains the most aggressive gynaecologic cancer with the ability to kill...
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Antiangiogéniques: les anciens et les nouveaux
Angiogenesis constitutes a major process in cancer progression, especially by promoting the growth of malignant cells and dissemination of...
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Thérapies ciblées dans le carcinome hépatocellulaire: indications et perspectives
For decades, therapeutic management of advanced-stage hepatocellular carcinoma (HCC) was hampered by marginal and limited benefit of conventional...
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Chimiothérapie de rattrapage par gemcitabine et docétaxel dans les sarcomes. Étude rétrospective monocentrique de 14 observations
AbstractThe sequential combination of gemcitabine (G) followed by docetaxel (D) is one of the rescue options for the treatment of recurrent soft...
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Place des antiangiogéniques dans le traitement des métastases pulmonaires secondaires au cancer rénal : à propos d’un cas clinique
In this study, the authors analyze the role of antiangiogenesis as a therapeutic target in the treatment of metastatic renal cancer through a...
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Résistance au docétaxel: mécanismes et applications thérapeutiques
Docetaxel is the standard treatment for metastatic castration-resistant prostate cancer (mCRPC) patients, but its effectiveness is limited in time...
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Maladie thromboembolique veineuse et cancer
Cancer is a real model of acquired hypercoagulable state. A close interaction exists between venous thromboembolic disease and cancer. Tumour...