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Showing 41-60 of 1,870 results
  1. Crystalline deposits in the cornea and various areas of the kidney as symptoms of an underlying monoclonal gammopathy: a case report

    Background

    Plasma cell dyscrasias (PCD) are characterized by an abnormal production of intact monoclonal immunoglobulins or parts such as heavy or...

    C. Lindemann, P. Enders, ... L. A. Völker in BMC Nephrology
    Article Open access 06 April 2021
  2. Update on kidney injury caused by multiple myeloma

    Multiple myeloma (MM) is a form of clonal plasma cell malignancy that associates with clinical manifestations such as anemia, hypercalcemia, bone...

    Linhui Wang, Chen Liu, ... Yiyao Deng in Annals of Hematology
    Article 28 June 2024
  3. Jan Gösta Waldenström and His World The Life and Work of a Giant in Science, Medicine and Humanity

    Jan Waldenström (1906-1996) was the leading Swedish internist of the twentieth century. The first chapter of the book presents his remarkable family...

    Frank Wollheim in Springer Biographies
    Book 2023
  4. Daratumumab with lenalidomide and dexamethasone in relapsed or refractory multiple myeloma patients – real world evidence analysis

    We performed real world evidence (RWE) analysis of daratumumab, lenalidomide and dexamethasone (Dara-Rd) versus lenalidomide and dexamethasone (Rd)...

    Martin Stork, Ivan Spicka, ... Ludek Pour in Annals of Hematology
    Article Open access 24 April 2023
  5. Prognosis of young patients with monoclonal gammopathy of undetermined significance (MGUS)

    Monoclonal gammopathy of undetermined significance (MGUS) is rare in young patients (age <40 years at diagnosis), with a prevalence of <0.3%,...

    Li Pang, S. Vincent Rajkumar, ... Shaji Kumar in Blood Cancer Journal
    Article Open access 01 February 2021
  6. POEMS syndrome with undetectable M-protein: a case report and literature review

    Background

    Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS) syndrome is a rare plasma cell (PC) neoplasm with...

    Han-Yue Xue, Lin Zhou, ... Fang Wei in Diagnostic Pathology
    Article Open access 07 June 2024
  7. Changing paradigms in diagnosis and treatment of monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM)

    Multiple myeloma (MM) is a highly heterogenous disease that exists along a continuous disease spectrum starting with premalignant conditions...

    Matthew Ho, Ashish Patel, ... Giada Bianchi in Leukemia
    Article 12 October 2020
  8. Effectiveness of tixagevimab/cilgavimab in patients with hematological malignancies as a pre-exposure prophylaxis to prevent severe COVID-19: a Czech retrospective multicenter study

    Despite lower virulence, the omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019...

    Ivo Demel, David Skopal, ... Roman Hájek in Annals of Hematology
    Article Open access 14 December 2023
  9. Multiple myeloma, a quintessential malignant disease of aging: a geroscience perspective on pathogenesis and treatment

    Multiple myeloma (MM) is an incurable plasma cell malignancy, which is predominantly a disease of older adults (the median age at diagnosis is...

    Veronika S. Urban, Andrea Cegledi, Gabor Mikala in GeroScience
    Article Open access 12 December 2022
  10. Differences in genomic abnormalities among African individuals with monoclonal gammopathies using calculated ancestry

    Multiple myeloma (MM) is two- to three-fold more common in African Americans (AAs) compared to European Americans (EAs). This striking disparity, one...

    Linda B. Baughn, Kathryn Pearce, ... S. Vincent Rajkumar in Blood Cancer Journal
    Article Open access 10 October 2018
  11. Scleroderma Mimics

    Scleroderma is named for the presence of its most characteristic quality, namely, skin sclerosis, in addition to symptoms that are commonly...
    Laura K. Hummers, Alan Tyndall in Scleroderma
    Chapter 2024
  12. Detection of MYD88 and CXCR4 mutations in cell-free DNA of patients with IgM monoclonal gammopathies

    Liquid biopsyis being integrated into cancer diagnostics with profound therapeutic implications. However, its role in Waldenström’s Macroglobulinemia...

    Tina Bagratuni, Ioannis Ntanasis-Stathopoulos, ... Meletios A. Dimopoulos in Leukemia
    Article Open access 19 July 2018
  13. Glomerulonephritis: immunopathogenesis and immunotherapy

    ‘Glomerulonephritis’ (GN) is a term used to describe a group of heterogeneous immune-mediated disorders characterized by inflammation of the...

    Hans-Joachim Anders, A. Richard Kitching, ... Paola Romagnani in Nature Reviews Immunology
    Article 12 January 2023
  14. Paraproteins Associated with Malignancy

    Monoclonal paraproteins and cryoglobulins with a monoclonal component are frequent in cancer patients. They may represent a poor prognostic index,...
    Pietro Enrico Pioltelli in Paraproteinemia and Related Disorders
    Chapter 2022
  15. Coexistent transthyretin amyloid cardiomyopathy and monoclonal gammopathy: Diagnostic challenges and prognostic implications

    Establishing an accurate diagnosis of amyloid subtype in patients with coexistent cardiac amyloidosis and monoclonal gammopathy is crucial due to...

    Katherine Lee Chuy, Javier Gomez, Saurabh Malhotra in Journal of Nuclear Cardiology
    Article 27 July 2020
  16. Giampaolo Merlini and the Pavia School

    The great advances in the diagnosis and treatment of cardiac amyloidosis are the result of a collective effort inspired by the pioneering work of a...
    Michele Emdin in Cardiac Amyloidosis
    Chapter 2024
  17. Systematic review and meta-analysis of the clinical features of MGRS

    Background

    It is crucial to identify patients with monoclonal gammopathy of renal significance (MGRS) from those without MGRS but with monoclonal...

    **gxue Du, Zhangxue Hu in BMC Nephrology
    Article Open access 16 January 2024
  18. Monoclonal Gammopathy of Undetermined Significance: Current Concepts and Future Prospects

    Purpose of the Review

    Monoclonal gammopathy of undetermined significance (MGUS) is a highly prevalent precursor condition in the general population,...

    Shivani Seth, Saurabh Zanwar, ... Prashant Kapoor in Current Hematologic Malignancy Reports
    Article 28 March 2020
  19. N-glycosylation of monoclonal light chains on routine MASS-FIX testing is a risk factor for MGUS progression

    Our group previously demonstrated that M-protein light chain (LC) glycosylation can be detected on routine MASS-FIX testing. Glycosylation is...

    Angela Dispenzieri, D. R. Larson, ... David Murray in Leukemia
    Article 27 June 2020
  20. Crystalglobulin-associated nephropathy presenting as MGRS in a case of monoclonal B-cell lymphocytosis: a case report

    Background

    Crystalglobulin-associated nephropathy (CAN), a rare subtype of monoclonal gammopathy, usually associated with multiple myeloma and...

    Rajib K. Gupta, Lois J. Arend, ... Ramya Bhargava in BMC Nephrology
    Article Open access 18 May 2020
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