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Safety and efficacy of intravenous thrombolysis in patients with acute ischemic stroke taking direct oral anticoagulants prior to stroke: a meta-analysis
BackgroundTo assess the safety and efficacy of intravenous thrombolysis (IVT) in patients with acute ischemic stroke (AIS) taking direct oral...
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PrevAleNce and Associated factors of inappropriaTe dosing of direct Oral anticoaguLants In pAtients with Atrial Fibrillation: the ANATOLIA-AF Study
PurposeInappropriate dosing of direct oral anticoagulants is associated with an increased risk of stroke, systemic embolism, major bleeding,...
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Direct Oral Anticoagulants: An Update on Monitoring and Antidotes for the Perioperative Physician
Purpose of ReviewThe purpose of this review is to update the clinician on assessing and reversing the effects of direct oral anticoagulants (DOACs)...
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Characterization of direct oral anticoagulants use in adult hematopoietic stem cell transplant recipients
Direct oral anticoagulants (DOACs) for venous thromboembolism (VTE) treatment are of interest in oncology due to ease of administration and lack of...
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Comparison of vitamin K and non-vitamin K oral anticoagulants and the bleeding frequency in the emergency department
IntroductionSafety studies of anticoagulant therapy have so far been conducted on many subjects in controlled conditions (i.e., clinically monitored)...
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An update on applications and limitations of direct oral anticoagulants
A major advancement in the field of medicine has been the introduction and usage of direct oral anticoagulants (DOACs) such as dabigatran (Pradaxa),...
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Direct oral anticoagulants: patient reported adherence and minor bleedings
Data regarding adherence and minor bleeding on direct oral anticoagulants in everyday life are still sparse. Inclusion criteria: treatment initiated...
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Employing Real-World Evidence for the Economic Evaluation of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation in Thailand
BackgroundThis study aimed to assess the cost-effectiveness of non-vitamin K antagonist oral anticoagulants (NOACs) in comparison with warfarin using...
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Non-vitamin K antagonist oral anticoagulants in adults with congenital heart disease
Despite an improved survival rate, cardiovascular accidents including thromboembolic events are a common cause of death in adults with congenital...
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When and How to Use Reversal Agents for Direct Oral Anticoagulants?
Purpose of ReviewOur objective is to describe currently available reversal agents for direct oral anticoagulants (DOACs), their target population,...
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Mortality after major bleeding in Asian atrial fibrillation patients receiving different direct oral anticoagulants: a nationwide, propensity score study
In this research, we assessed mortality after major bleeding events in atrial fibrillation (AF) patients taking four direct oral anticoagulants...
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Nonvitamin K oral anticoagulants with proton pump inhibitor cotherapy ameliorated the risk of upper gastrointestinal bleeding
Proton pump inhibitors (PPIs) can reduce the risk of upper gastrointestinal bleeding (UGIB) in patients who are taking oral anticoagulants. This...
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Effectiveness and safety of continuous low-molecular-weight heparin versus switching to direct oral anticoagulants in cancer-associated venous thrombosis
Given the existing uncertainty regarding the effectiveness and safety of switching from low-molecular-weight heparin (LMWH) to direct oral...
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Underutilization of anticoagulants in patients with nonvalvular atrial fibrillation in the era of non-vitamin K antagonist oral anticoagulants
BackgroundNon-vitamin K antagonist oral anticoagulants (NOACs) are preferred over vitamin K antagonists (VKAs) as oral anticoagulant (OAC) therapy in...
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Do anticoagulants impact the “in-house mortality” after surgical treatment of proximal femoral fractures—a multivariate analysis
PurposeThe prevalence of proximal femur fractures is increasing with rising population age. Patients are presenting with more comorbidities....
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The effect of corticosteroids, antibiotics, and anticoagulants on the development of post-COVID-19 syndrome in COVID-19 hospitalized patients 6 months after discharge: a retrospective follow up study
To assess the effect of pharmacotherapeutic interventions commonly employed in the management of COVID-19 hospitalized patients on the development of...
