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A real-world comparison of tisagenlecleucel and axicabtagene ciloleucel CAR T cells in relapsed or refractory diffuse large B cell lymphoma
Axicabtagene ciloleucel (axi-cel) and tisagenlecleucel (tisa-cel) have both demonstrated impressive clinical activity in relapsed/refractory (R/R)...
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Associations of circulating advanced glycation end products and their soluble receptors with cancer risk: A systematic review and meta-analysis of observational studies
Advanced glycation end products (AGE) in complex with their receptors (RAGE) cause a chronic inflammatory state in the body, which is the major...
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Outcomes of first therapy after CD19-CAR-T treatment failure in large B-cell lymphoma
Persistence or recurrence of large B-cell lymphoma after CD19-CAR-T is common, yet data guiding management are limited. We describe outcomes and...
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A phase 2 study of axicabtagene ciloleucel in relapsed or refractory large B-cell lymphoma in Japan: 1-year follow-up and biomarker analysis
Axicabtagene ciloleucel (axi-cel) is an autologous, CD19-targeting chimeric antigen receptor T‑cell therapy. We recently reported the 3-month...
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Shape correspondence for cel animation based on a shape association graph and spectral matching
We present an effective spectral matching method based on a shape association graph for finding region correspondences between two cel animation...
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Reducing and controlling metabolic active tumor volume prior to CAR T-cell infusion can improve survival outcomes in patients with large B-cell lymphoma
Bridging therapy before CD19-directed chimeric antigen receptor (CAR) T-cell infusion is frequently applied in patients with relapsed or refractory...
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Engineered T Cells: CAR T Cell Therapy and Beyond
Purpose of ReviewThis article reviews the current data and future directions of engineered T cell therapies in non-Hodgkin lymphomas.
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Matching-adjusted indirect treatment comparison of chimeric antigen receptor T-cell therapies for third-line or later treatment of relapsed or refractory large B-cell lymphoma: lisocabtagene maraleucel versus tisagenlecleucel
BackgroundThere are no head-to-head clinical studies comparing chimeric antigen receptor (CAR) T-cell therapies for the treatment of relapsed or...
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WHO-Klassifikation 2022 chronischer myeloproliferativer Erkrankungen
BackgroundHuman neoplasms of various organ systems are being hierarchically cataloged by the World Health Organization (WHO) in a unified relational...
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The progress of novel strategies on immune-based therapy in relapsed or refractory diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) can be cured with standard front-line immunochemotherapy, whereas nearly 30–40% of patients experience...
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Eosinophilie: hypereosinophiles Syndrom versus eosinophile Granulomatose mit Polyangiitis
Hypereosinophilic syndrome (HES) is defined as a peripheral eosinophil count of > 1500/μl (assessed twice at an interval of ≥ 2 weeks) and an...
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Hematologic malignancies following immune checkpoint inhibition for solid tumors
Immune checkpoint inhibition (ICI) can induce durable responses in patients with advanced malignancies. Three cases of hematological neoplasia...
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Melatonin Language in Postharvest Life of Horticultural Crops
During postharvest life, fresh horticultural crops suffer from sensory and nutritional quality deterioration accompanied by fungal decay incidence....
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Axicabtagene ciloleucel as first-line therapy in high-risk large B-cell lymphoma: the phase 2 ZUMA-12 trial
High-risk large B-cell lymphoma (LBCL) has poor outcomes with standard first-line chemoimmunotherapy. In the phase 2, multicenter, single-arm ZUMA-12...
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Novel CD19-specific γ/δ TCR-T cells in relapsed or refractory diffuse large B-cell lymphoma
BackgroundT cell receptor (TCR)-T cells possess similar effector function, but milder and more durable signal activation compared with chimeric...
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Study of the Production of Sodium Hydroxide by Bipolar Electrodialysis from Sodium Carbonate Solution
AbstractIn this work, the production of sodium hydroxide by the method of bipolar electrodialysis from a solution of sodium carbonate using bipolar...
