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Polyphenols as possible alternative agents in chronic fatigue: a review
Chronic fatigue syndrome (CFS) is a pathological state of extreme tiredness that lasts more than six months and may possess an impact on the social,...
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Immunomodulating Agents for Pediatric Ear, Nose, and Throat Infections
Upper respiratory infections are prevalent in the childhood period. Upper respiratory tract infections (URTIs) include nasopharyngitis (common cold),... -
Synthesis, Characterization, and Biological Evaluation of Novel Thiadiazole-incorporated Aminothiazole Derivatives as Potential Anticancer Agents
AbstractA series of novel thiadiazole-incorporated aminothiazole derivatives were synthesized and characterized by IR and 1 H NMR and 13 C NMR...
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Treatment of Non-Infectious Corneal Injury: Review of Diagnostic Agents, Therapeutic Medications, and Future Targets
Corneal injuries can occur secondary to traumatic, chemical, inflammatory, metabolic, autoimmune, and iatrogenic causes. Ocular infection may...
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Role of adiponectin, resistin and monocyte chemo-attractant protein-1 in overweight/obese asthma phenotype in children
BackgroundAsthma is a chronic inflammatory disorder of the airways with diverse overlap** pathologies and phenotypes contributing to a significant...
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Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airways
IntroductionThe standard therapy for bronchial asthma consists of combinations of acute (short-acting ß 2 -sympathomimetics) and, depending on the...
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Asthma History, Current Situation, an Overview of Its Control History, Challenges, and Ongoing Management Programs: An Updated Review
Asthma is a disease of the airways that is characterized by chronic inflammation and disordered airway function. The purpose of writing the current...
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LC–MS profiling, in vitro and in silico C-ABL kinase inhibitory approach to identify potential anticancer agents from Dalbergia sissoo leaves
Belonging to the Fabaceae family, Dalbergia sissoo , a versatile plant, has gained prominence for its potent medicinal attributes, especially...
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Therapeutic Potential of Plantamajoside
Plantamajoside is a phenylpropanoid glycoside that can be extracted from Plantago asiatica L., Plantaginaceae. It is one of the most extensively...
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Cardiovascular Agents
Cardiovascular agents are utilized when myocardial and/or circulatory dysfunction persists despite optimization of volume status. They have potent... -
Meteorin-β/Meteorin like/IL-41 attenuates airway inflammation in house dust mite-induced allergic asthma
We sought to examine the regulatory effect of Meteorin-β (Metrnβ)/Meteorin like (Metrnl)/IL-41 on lung inflammation in allergic asthma. We found that...
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Polystichum braunii ameliorates airway inflammation by attenuation of inflammatory and oxidative stress biomarkers, and pulmonary edema by elevation of aquaporins in ovalbumin-induced allergic asthmatic mice
Asthma is a chronic inflammation of pulmonary airways associated with bronchial hyper-responsiveness. The study was aimed to validate the folkloric...
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Lipopeptide Pepducins as Therapeutic Agents
Pepducins are lipidated peptides that target the intracellular loops of G protein-coupled receptors (GPCRs) in order to modulate transmembrane... -
Attenuation of ovalbumin-induced inflammation and lung oxidative injury in asthmatic rats by Zingiber officinale extract: combined in silico and in vivo study on antioxidant potential, STAT6 and TNF-α pathways
In the present study we focused on the anti-asthmatic and antioxidant effects of Zingiber officinalis roscoe L. (ZO) aqueous extract. This study...
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Maternal Use of Anti-asthmatic Drugs and Infant Congenital Malformations
Most likely there is an association between maternal use of anti-asthmatic drugs and infant congenital malformations. It is not strong and appears... -
Phenome-wide causal associations between osteoarthritis and other complex traits through the latent causal variable analysis
BackgroundIndividuals with osteoarthritis present with comorbidities, and the potential causal associations remain incompletely elucidated. The...
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Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models
Asthma is a common respiratory disease associated with airway hyperresponsiveness (AHR), airway inflammation and mast cell (MC) accumulation in the...
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Nasal Polyposis and Nonsteroidal Anti-inflammatory Drug-Exacerbated Respiratory Disease
Nonsteroidal anti-inflammatory drug-exacerbated respiratory disease (NERD) is a phenotype of nasal polyposis. The coexistence of asthma, persistent... -
Asthma-Induced Inflammatory Responses and Reversal by Botanicals
Asthma is the most prevailing chronic inflammatory medical condition which is the outcome of extensive air pollution and which is associated with... -
Asthma and COVID-19: a dangerous liaison?
The coronavirus disease 2019 (COVID-19) pandemic, caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), provoked the most...