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Gene Family Classification Using Machine Learning: A Comparative Analysis
Accurate classification of gene families is of utmost importance in comprehending the functional roles and evolutionary history of genes within a... -
Visualization of Defined Gene Sequences in Single Nuclei by DNA In Situ Hybridization (DISH)
Gains and/or losses of large genomic loci such as full or partial aneuploidies/aneusomies can be routinely identified in single cells using... -
Gene Sequence Assembly and Application
Sequencing and gene sequence assembly are the first steps in the process of genome-wide association studies (GWAS), in which gene fragments obtained... -
Joint analysis of microsatellites and flanking sequences enlightens complex demographic history of interspecific gene flow and vicariance in rear-edge oak populations
Inference of recent population divergence requires fast evolving markers and necessitates to differentiate shared genetic variation caused by...
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Molecular characterization and haplotypes of hydatid cyst isolates collected from humans and ruminants in Setif Province (northeast of Algeria) based on mitochondrial cytochrome C oxidase subunit 1 (mt-CO1) gene sequences
Cystic echinococcosis (CE) is a disease that can be transmitted from animals to humans, caused by the metacestode of Echinococcus granulosus . The...
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The invasive land flatworm Arthurdendyus triangulatus has repeated sequences in the mitogenome, extra-long cox2 gene and paralogous nuclear rRNA clusters
Using a combination of short- and long-reads sequencing, we were able to sequence the complete mitochondrial genome of the invasive ‘New Zealand...
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MiDAS 4: A global catalogue of full-length 16S rRNA gene sequences and taxonomy for studies of bacterial communities in wastewater treatment plants
Microbial communities are responsible for biological wastewater treatment, but our knowledge of their diversity and function is still poor. Here, we...
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Complementary Alu sequences mediate enhancer–promoter selectivity
Enhancers determine spatiotemporal gene expression programs by engaging with long-range promoters
1 –4 . However, it remains unknown how enhancers find... -
Pig pangenome graph reveals functional features of non-reference sequences
BackgroundThe reliance on a solitary linear reference genome has imposed a significant constraint on our comprehensive understanding of genetic...
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Gene Drives
A “gene drive” is a version of gene editing—a newer, more precise way to change a DNA (or RNA) sequence; in this case, combining a guide RNA with an... -
An Ensemble-Based Phenotype Classifier to Diagnose Crohn’s Disease from 16s rRNA Gene Sequences
In the past few years, one area of bioinformatics that has sparked special interest is the classification of diseases using machine learning. This is... -
Comparative Study of Two Himalayan Snow Trouts, Schizothorax esocinus and Schizothorax curvifrons Within the Schizothoracinae and Other Nearest Relatives of Cyprinidae, Inferred from Mitochondrial Sequences of Cytochrome b (Cyt-b) and Cytochrome Oxidase I (Co-I) Gene
The Himalayan region encompasses varied aquatic ecosystems, characterized by the presence of diverse ichthyofauna, particularly represented by...
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Regulation of Gene Expression by Synthetic DNA-Binding Ligands
During the past 20 years, polyamides have evolved from the natural product distamycin to a new class of programmable heterocyclic oligomers that bind... -
Intraspecific Differentiation of Asian Pink Salmon Inferred from the Mitochondrial cytb Gene Sequences
AbstractThe study is focused on intraspecific genetic polymorphism of pink salmon. The uniqueness of this representative of the Pacific salmon of the...
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Genetics and evolutionary insights from Solanaceae genome sequences
The availability of genome sequence resources and genomic information enables the functional characterization of genes in crop plants. These genes...
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Accurately clustering biological sequences in linear time by relatedness sorting
Clustering biological sequences into similar groups is an increasingly important task as the number of available sequences continues to grow...
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Nuclear sequences of mitochondrial origin in domestic yak
Mitochondrial DNA sequences are frequently transferred into the nuclear genome, generating nuclear mitochondrial DNA sequences (NUMTs). Here, we...
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Phylogeny of the Dipus sagitta Species Complex by Nuclear Gene Sequences
The northern three-toed jerboa Dipus sagitta had long been considered to be a single polytypic species. High genetic diversity of D. sagitta was...
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Computational Linguistics and Biological Sequences in Artificial Intelligence
Researchers generally believe that nucleic acid is also a language with rich information. Nucleic acid languageNucleic acid language can be used to...