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The SNP rs460089 in the gene promoter of the drug transporter OCTN1 has prognostic value for treatment-free remission in chronic myeloid leukemia patients treated with imatinib
Membrane transporters are important determinants of drug bioavailability. Their expression and activity affect the intracellular drug concentration...
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Investigating the early impacts of the COVID-19 pandemic on modifiable risk factors for cancer and chronic disease: a repeated cross-sectional study in Alberta, Canada
ObjectivesThis study contributes to empirical evidence by examining the impact of the first and second waves of the COVID-19 pandemic on modifiable...
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Magnetorheological Fluids
A Magnetorheological fluid (MRF) is a suspension of micron-sized ferromagnetic particles in a nonmagnetic carrier fluid, including some additives... -
Comparison of the Seismic Performance of Steel Moment-Resisting Frames and Moment-Resisting Knee Braced Frames
Ductile steel moment-resisting frame (MRF) structures offer an ideal solution to resist seismic loads in high seismic regions due to their reliable... -
A new magnetorheological quasi-zero stiffness vibration isolation system with large zero stiffness range and highly stable characteristics
Various quasi-zero stiffness (QZS) systems have been developed and applied in the vibration control domain in recent years. However, most QZS systems...
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Efficient and Performance-Based Design Method for Seismic Resistance of Steel MRF Structure with Nonlinear Viscous Dampers
Investigated is a simplified design procedure (SDP) for performance-based seismic design of low-rise new steel moment resisting frame (MRF) buildings... -
Approximate Methods to Estimate Residual Drift Demands in Steel Structures with Viscous Dampers Designed by the DDBD Approach
Nowadays, using performance-based design procedures are widely applied by structural engineers. The direct displacement-based design (DDBD) approach...
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Design, Analysis and Assessment of MRFs Equipped with FREEDAM Connections and Designed by TPMC: Comparison with Traditional Connections
Moment Resisting Frames were designed according to the Theory of Plastic Mechanism Control specialized for use in the Ductility Classes proposed in... -
Comparison of thoracic epidural and thoracic erector spinae plane block for pain relief of posterolateral rib fractures—a retrospective cohort study
BackgroundPain from rib fractures (posterior/lateral/anterior) is associated with significant pulmonary morbidity. Earlier epidural and paravertebral...
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Seismic response of mid-rise steel MRFs: the role of geometrical irregularity, frequency components of near-fault records, and soil-structure interaction
Near-fault (NF) ground motions may induce higher demands on structures compared to far-fault records. This is often due to the velocity pulses,...
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The added values of 18F-FDG PET/CT in differentiating cancer recurrence and osteoradionecrosis of mandible in patients with treated oral squamous cell carcinoma
BackgroundOsteoradionecrosis (ORN) of the jaw requires a differential diagnosis to exclude cancer recurrence. Here, we sought to develop a scoring...
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Probabilistic Fragility Analysis of Smart Steel Moment-Resisting Frame Structure Subjected to Intentional Blast Loading
The fragility functions are obtained for steel Moment Resisting Frame structures (MRFs) equipped with Nickle Titanium Shape Memory Alloy (NiTi SMA),... -
Probabilistic Seismic Resilience Evaluation of Smart Steel Frame
This study investigates the resilience of smart steel moment-resisting frames (MRFs) equipped with nickel-titanium shape memory alloy connections... -
Post-earthquake Behavior of Steel Moment Resisting Frames with Connections Modified by Introducing Reduced Beam Section (RBS)
The beam-to-column connections are the most vulnerable locations in steel Moment Resisting Frames (MRFs) subjected to seismic loading. The cyclic...
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Stability of wide-flange columns in steel moment-resisting frames: evaluation of the Canadian seismic design requirements
This paper aims to evaluate the seismic stability of wide-flange columns of steel moment-resisting frames (MRFs) with emphasis on the 2019 Canadian...
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Enhanced Seismic Efficiency and Resiliency of Steel-Frame Buildings Using Viscous-Dampers
The focus of this paper is on quantifying and assessing the seismic response of a steel building consisting of moment-resisting frames (MRFs) and... -
Evaluation of pounding effects between reinforced concrete frames subjected to far-field earthquakes in terms of damage index
In this paper, three different damage indexes were used to detect nonlinear damages in two adjacent Reinforced Concrete (RC) structures considering...
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Post-transcriptional regulation of myogenic transcription factors during muscle development and pathogenesis
The transcriptional regulation of skeletal muscle (SKM) development (myogenesis) has been documented for over 3 decades and served as a paradigm for...
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Application of Steel and FRP Reinforcement Combination in Moment Resisting Frames: Prospects and Challenges
The demand for seismic resilient communities is the main driving force behind efforts of research engineers to develop novel reinforced concrete... -
Seismic Upgradation of Moment Resisting Frame Structures Using Buckling-Inhibited Shear Yielding Dampers
Seismic response control of structures has been studied to minimize damage and economic losses for many years now. Researchers have developed...