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Efficacy and safety of romosozumab: a meta-analysis of placebo-controlled trials
IntroductionWe aimed to comprehensively compile placebo-controlled trials on the efficacy and safety of romosozumab (210 mg, subcutaneously, once...
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Risk factors for false positive and false negative MRI in diagnosing medial and lateral meniscal tears with concomitant ACL injury
ObjectiveTo determine the diagnostic performance of MRI in evaluating meniscal abnormalities in the setting of anterior cruciate ligament (ACL)...
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Evidence-based clinical practice guidelines for the management of acute ankle injuries according to: a PRISMA systematic review and quality appraisal with AGREE II
BackgroundAcute ankle injuries are commonly seen in emergency rooms, with significant social impact and potentially devastating consequences. While...
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Does ponticulus posticus affect vertebral artery diameter
PurposePonticulus Posticus, atlantooccipital ligament ossification-induced anomaly, surrounds the vertebral artery and the first cervical nerve root....
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[18F]-D3FSP β-amyloid PET imaging in older adults and alzheimer’s disease
Purpose[ 18 F]-D3FSP is a new β-amyloid (Aβ) PET imaging tracer designed to decrease nonspecific signals in the brain by reducing the formation of the...
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Prospective investigation of amino acid transport and PSMA-targeted positron emission tomography for metastatic lobular breast carcinoma
PurposeTo explore the feasibility of imaging amino-acid transport and PSMA molecular pathways in the detection of metastatic breast invasive lobular...
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Synovial calprotectin in prosthetic joint infection. A systematic review and meta-analysis of the literature
IntroductionCalprotectin is a protein endowed with antimicrobial properties, rendering it a distinctive marker for infection. Two methods are...
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Increased Risk of Severe Cardiovascular Events Following Exacerbations of Chronic Obstructive Pulmonary Disease: Results of the EXACOS-CV Study in Japan
IntroductionSevere exacerbations of chronic obstructive pulmonary disease (COPD) are known to increase the risk of cardiovascular events. However,...
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Impacts of X-linked Retinitis Pigmentosa and Patient Pathways in European Countries: Results from the Cross-sectional EXPLORE XLRP-1 Physician Survey
IntroductionX-linked retinitis pigmentosa (XLRP) is a rare, incurable, vision-threatening, genetic disease. In this study, we aimed to reveal the...
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Usability of the SB11 Pre-filled Syringe (PFS) in Patients with Retinal Diseases
IntroductionSB11 (Byooviz™; Samsung Bioepis Co., Ltd.) is a ranibizumab (Lucentis ® ; Genentech, Inc.) biosimilar targeting vascular endothelial...
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A Canadian Retrospective Chart Review Evaluating Concomitant Methotrexate De-escalation Patterns in Patients with Rheumatoid Arthritis Treated with Biologic or Targeted Synthetic DMARDs
IntroductionRheumatoid arthritis (RA) guidelines recommend methotrexate (MTX)-anchored therapy with biologic or targeted synthetic disease-modifying...
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Clinical performance of the ASAS health index in chinese patients with ankylosing spondylitis and its influencing factors
ObjectiveThe aim of this study was to investigate the status of health-related quality of life in Chinese patients with ankylosing spondylitis (AS)...
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Characteristics of Neonatal Sepsis and Predictive Values of Polyfunctional Assessment of Umbilical Cord Neutrophils Based on Single Cell Proteomic Secretion
The early diagnosis of neonatal sepsis is crucial as it remains a prevalent cause of neonatal mortality. In this study, we conducted an analysis on...
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Mechanisms of osteoporosis associated with chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a disease characterized by chronic respiratory symptoms due to inflammatory and destructive changes...
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A protocol for sco** reviews on the role of whole-body and dedicated body-part magnetic resonance imaging for assessment of adult and juvenile idiopathic inflammatory myopathies
Currently, standardized magnetic resonance imaging (MRI) scoring systems and protocols for assessment of idiopathic inflammatory myopathies (IIMs) in...
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Age-adjusted Charlson Comorbidity Index as an effective tool for the choice between simultaneous or staged bilateral total knee arthroplasty
IntroductionThe choice between simultaneous and staged bilateral total knee arthroplasty (BTKA) remains controversial. Age-adjusted Charlson...
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Is still effective massive allograft reconstruction in parosteal osteosarcoma of the distal femur? Review of the literature and advantages of newer technologies
PurposeParosteal Osteosarcoma is a well-differentiated, low-grade bone sarcoma. It most commonly occurs in the third decade of life, usually in the...
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Increased risk of hip and major osteoporotic fractures in 8463 patients who have undergone stem cell transplantation, a Swedish population-based study
SummaryIn this retrospective cohort study of adult stem cell transplanted patients ( n = 8463), a significant increased risk of both MOF and hip...