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Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
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Long-Term Follow-Up before and during Riluzole Treatment in Six Patients from Two Families with Spinocerebellar Ataxia Type 7
BackgroundCurrently no curative treatment exists for spinocerebellar ataxias (SCAs). Riluzole repurposing was proposed as a symptomatic treatment in...
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Complementary and Alternative Medicine for Autism – A Systematic Review
Complementary and Alternative Medicine (CAM) is a therapeutic option currently used by autistic people with continued interest and uptake. There...
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Resveratrol Modulates Diabetes-Induced Neuropathic Pain, Apoptosis, and Oxidative Neurotoxicity in Mice Through TRPV4 Channel Inhibition
Diabetic peripheral neuropathy (DPN) is caused by several factors, including reactive free oxygen radicals (ROS)-induced excessive Ca 2+ influx....
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Mirror game as a tool to influence interpersonal spontaneous behavior after performance
Mirror game (MG) is an exercise in which participants imitate each other. Our study explored its spontaneous behavioral consequences after...
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N-methyl-D-aspartate Receptor Subunits 2A and 2B Mediate Connexins and Pannexins in the Trigeminal Ganglion Involved in Orofacial Inflammatory Allodynia during Temporomandibular Joint Inflammation
Temporomandibular joint osteoarthritis (TMJOA) is a severe form of temporomandibular joint disorders (TMD), and orofacial inflammatory allodynia is...
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ENTPD1 (CD39) and NT5E (CD73) expression in human medulloblastoma: an in silico analysis
Medulloblastoma is the most common malignant tumor in the pediatric population. Its classification has incorporated key molecular variations...
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Protein Phosphatase 2ACα Regulates ATR-Mediated Endogenous DNA Damage Response Against Microcephaly
Protein phosphatase 2A (PP2A) is an abundant heterotrimeric holoenzyme in eukaryotic cells coordinating with specific kinases to regulate...
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Thioredoxin-1 Protects Neurons Through Inhibiting NLRP1-Mediated Neuronal Pyroptosis in Models of Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common neurodegenerative disease all over the world. In the last decade, accumulating proofs have evidenced that...
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Neural basis of lower-limb visual feedback therapy: an EEG study in healthy subjects
BackgroundVideo-feedback observational therapy (VOT) is an intensive rehabilitation technique based on movement repetition and visualization that has...
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STED Imaging of Vesicular Endocytosis in the Synapse
Endocytosis is a fundamental biological process that couples exocytosis to maintain the homeostasis of the plasma membrane and sustained...
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Generative Modelling of Cortical Receptor Distributions from Cytoarchitectonic Images in the Macaque Brain
Neurotransmitter receptor densities are relevant for understanding the molecular architecture of brain regions. Quantitative in vitro receptor...
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Spinal cord lesion MRI and behavioral outcomes in a miniature pig model of spinal cord injury: exploring preclinical potential through an ad hoc comparison with human SCI
Study designprospective case series of Yucatan miniature pig spinal cord contusion injury model with comparison to human cases of spinal cord injury...
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Parental Inflammatory Bowel Disease with Child Autism: A Comprehensive Review and Meta-Analysis
Inflammatory bowel disease (IBD) has been shown to be connected to a greater possibility of neurologically developed problems, such as autism...
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Controlling Alzheimer’s disease by deep brain stimulation based on a data-driven cortical network model
This work aims to explore the control effect of DBS on Alzheimer's disease (AD) from a neurocomputational perspective. Firstly, a data-driven...
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Applications of machine learning to MR imaging of pediatric low-grade gliomas
IntroductionMachine learning (ML) shows promise for the automation of routine tasks related to the treatment of pediatric low-grade gliomas (pLGG)...
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Adherence and Opportunity Frequency as Predictors of Communication Outcomes from Pivotal Response Parent Training
PurposeAccess to intervention is a barrier for children with autism. As parent-mediated interventions have emerged to address this need,...
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Muscle MRI as a biomarker of disease activity and progression in myotonic dystrophy type 1: a longitudinal study
IntroductionMyotonic dystrophy type 1 (DM1) is an autosomal dominant disease characterized by myotonia and progressive muscular weakness and atrophy....
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The risks for major psychiatric disorders in the siblings of probands with major depressive disorder
Using a case-controlled study including siblings of major depression (MD) and control probands, born 1970–1990 and followed through 2018, we sought...
