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Enzyme-Catalyzed Regio- and Enantioselective Ketone Reductions
In this chapter, examples are given of the application of highly reactive prochiral ketones as substrates for enzymatic reductions....
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Aquaculture of “Non-Food Organisms” for Natural Substance Production
Marine invertebrates are already sources of commercially important secondary metabolites and may become even more so as knowledge on marine...
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Downstream Processing in Marine Biotechnology
Downstream processing is one of the most underestimated steps in bioprocesses and this is not only the case in marine biotechnology. However, it...
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Marine Enzymes
Marine enzyme biotechnology can offer novel biocatalysts with properties like high salt tolerance, hyperthermostability, barophilicity, cold...
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Industrial Enzymatic Production of Cephalosporin-Based β-Lactams
Cephalosporins are chemically closely related to penicillins both work by inhibiting the cell wall synthesis of bacteria. The first generation...
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Technical Application of Biological Principles in Asymmetric Catalysis
The production of enantiopure compounds is becoming increasingly important to the chemical and biotechnological industries. Bioorganic...
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Compartmentalization and Transport in β-Lactam Antibiotics Biosynthesis
Classical strain improvement of β-lactam producing organisms by random mutagenesis has been a powerful tool during the last century. Current insights...
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Regulation of Penicillin Biosynthesis in Filamentous Fungi
The β-lactam antibiotic penicillin is one of the mainly used antibiotics for the therapy of infectious diseases. It is produced as end product by...
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Extraction of Primary and Secondary Metabolites
Several new methods besides the usual organic solvent extraction have been developed over the last few years for the extraction of primary and...
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Biochemistry and General Genetics of Nonribosomal Peptide Synthetases in Fungi
Peptides like penicillin or cyclosporin are nonribosomally synthesised by large multifunctional enzymes. Peptide synthetase genes are coexpressed...
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Staphylococcal alpha-toxin
Staphylococcal alpha-toxin, archetype of an oligomerizing pore-forming toxin, is produced and secreted as a water-soluble 34 kD monomer. High...
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Shiga toxins and their mechanisms of cell entry
The Shiga toxins (Stxs) are related toxins secreted by Shigella dysenteriae, Escherichia coli in addition to other bacteria. They all act by entering...
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Duplication of genes and genomes in yeasts
The molecular evolution of the group of yeasts closely related to Saccharomyces cerevisiae has been profoundly affected by an ancient polyploidy...
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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive...
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Thalassospira aquimaris sp. nov. and Winogradskyella marincola sp. nov. two marine bacteria isolated from an agar-degrading co-culture
Two novel Gram-stain-negative, aerobic, and non-motile strains, designated FZY0004 T and YYF002 T , were isolated from an agar-degrading co-culture,...
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Redundancy in microbiota-mediated suppression of the soybean cyst nematode
BackgroundSoybean cyst nematodes (SCN) as animal parasites of plants are not usually interested in killing the host but are rather focused on...
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Prophylactic Effect and Antiulcerogenic Potential of Probiotic Lactiplantibacillus plantarum E1K2R2 and its Exopolysaccharide Against Ibuprofen-Induced Acute Gastric Ulcer
Lactiplantibacillus plantarum ( Lpb. plantarum ), as a safe probiotic microorganism, has been documented for its production of multiple bioactive...
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Fish Iridoviridae: infection, vaccination and immune response
Each year, due to climate change, an increasing number of new pathogens are being discovered and studied, leading to an increase in the number of...
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Engineered plastic-associated bacteria for biodegradation and bioremediation
The global plastic waste crisis has triggered the development of novel methods for removal of recalcitrant polymers from the environment....
