Search
Search Results
-
Heart Valve Regeneration
The valves of the heart cannot regenerate spontaneously. Therefore, heart valve disease generally necessitates surgical repair or replacement of the...
-
Rhenium and Technetium Complexes Anchored by Phosphines and Scorpionates for Radiopharmaceutical Applications
This review presents a comprehensive overview of the most significant developments in the chemistry of technetium and rhenium complexes anchored by...
-
The Use of N-Heterocyclic Carbenes as Ligands in Palladium-Mediated Catalysis
Recent developments in the use of N-heterocyclic carbenes (NHC) as ligands in palladium-mediated transformations are described. These versatile...
-
Catalytic Processes Involving β-Carbon Elimination
Palladium-catalyzed C–C bond cleavage via β-carbon elimination occurs in various cyclic and acyclic systems. Thus, the reaction can be utilized as...
-
Theoretical Studies of C-H σ-Bond Activation and Related Reactions by Transition-Metal Complexes
Many σ-bond activation reactions are classified into two main categories, oxidative addition and metathesis, except for several examples. Important...
-
Late Transition Metals as Homo- and Co-Polymerization Catalysts
In the present account we address two aspects of the polymerization processes catalyzed by the late-transition-metal complexes: (i) influence of the...
-
Applications of Organotitanium Reagents
Organometallic transformations involving titanium are employed both catalytically and stoichiometrically in the pharmaceutical and fine chemical...
-
Construction of Carbocycles via Zirconacycles and Titanacycles
Metal-mediated selective construction of useful carbocyclic compounds from multi-component reaction systems has attracted much attention in recent...
-
Chiral-at-Metal Complexes as Asymmetric Catalysts
In general, asymmetric catalysts are based on the combination of a chiral organic ligand and a metal ion. Here we show that future research should...
-
Simultaneous In Vivo Regeneration of Neodermis, Epidermis, and Basement Membrane
Full-thickness skin loss does not undergo complete spontaneous regeneration in mammals. To restore the normal function of skin, dermal and epidermal...
-
DNA Major Groove Binders: Triple Helix-Forming Oligonucleotides, Triple Helix-Specific DNA Ligands and Cleaving Agents
Nucleic acids are polymorphic macromolecules that can adopt a variety of single-, double- and multi-stranded conformations, which in turn may provide...
-
Structural Selectivity of Drug-Nucleic Acid Interactions Probed by Competition Dialysis
Competition dialysis is a powerful new tool for the discovery of ligands that bind to nucleic acids with structural- or sequence-selectivity. The...
-
Palladium-Catalyzed Annulation of Alkynes
Palladium readily catalyzes the cross-coupling of functionally substituted aryl or vinylic halides and alkynes to afford a wide variety of...
-
Palladium-Catalyzed Two- or Three-Component Cyclization of Functionalized Allenes
This review summarizes the Pd-catalyzed cyclization of an allene bearing a nucleophilic functionality with an organic or inorganic halide, and the...
-
Nucleophilic Attack by Palladium Species
Recent researches have revealed that certain allyl-, vinyl-, and arylpalladium intermediates show a nucleophilic nature and react with various...
-
Transition Metal Catalyzed σ-Bond Activation and Formation Reactions
The factors controlling the transition metal catalyzed σ-bond (including H-H, C-H and C-C) activation and formation, the fundamental steps of many...
-
Palladium-Catalyzed Heck Arylations in the Synthesis of Active Pharmaceutical Ingredients
The utility of inter- and intramolecular Heck arylations in the synthesis of intermediates for the preparation of active pharmaceutical ingredients...
-
Chiral Ureas and Thiroureas in Asymmetric Catalysis
After an overview of chiral urea and thiourea synthetic methods, this review describes the main applications of urea and thiourea complexes in...
-
Development of Transition Metal-Mediated Cyclopropanation Reactions
A brief discussion of the methods for cyclopropane formation emphasizing organometallic reagents and catalysts is followed by several examples of the...
-
Metallocene-Catalyzed Selective Reactions
Transition metal cyclopentadienyl complexes constitute a large family of compounds that can be used as catalyst for a number of organic...