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Long-range inhibition from prelimbic to cingulate areas of the medial prefrontal cortex enhances network activity and response execution
It is well established that the medial prefrontal cortex (mPFC) exerts top-down control of many behaviors, but little is known regarding how...
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FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs
The Ser/Thr protein phosphatase 2 A (PP2A) regulates the dephosphorylation of many phosphoproteins. Substrate recognition are mediated by B...
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Combined MediaPipe and YOLOv5 range of motion assessment system for spinal diseases and frozen shoulder
Spinal diseases and frozen shoulder are prevalent health problems in Asian populations. Early assessment and treatment are very important to prevent...
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Administration of an antibody against apoptosis inhibitor of macrophage prevents aortic aneurysm progression in mice
Apoptosis inhibitor of macrophage (AIM) is known to induce apoptosis resistance in macrophages and to exacerbate chronic inflammation, leading to...
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Habitat radiomics and deep learning fusion nomogram to predict EGFR mutation status in stage I non-small cell lung cancer: a multicenter study
Develop a radiomics nomogram that integrates deep learning, radiomics, and clinical variables to predict epidermal growth factor receptor (EGFR)...
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Damage evolution law of multi-hole blasting igneous rock and quantitative evaluation model of damage degree based on fractal theory and clustering algorithm
The geological phenomenon of igneous rock invading coal seam is widely distributed, which induces mining risk and affects efficient mining. The...
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Formulation of silver phosphate/graphene/silica nanocomposite for enhancing the photocatalytic degradation of trypan blue dye in aqueous solution
Photocatalytic degradation of several harmful organic compounds has been presented as a potential approach to detoxify water in recent decades....
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A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in a pancreatic cancer cell line
Pancreatic adenocarcinoma is one of the most aggressive and lethal forms of cancer. Chemotherapy is the primary treatment for pancreatic cancer, but...
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Study on the reduction of residual stress in laser cladding layers through groove texture
In order to develop a method for the production of crack-free cladding layers, we combined surface texturing technology with laser cladding,...
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Initiating-clone analysis in patients with acute myeloid leukemia secondary to essential thrombocythemia
Most of essential thrombocythemia (ET) patients have the clone harboring a mutation in one of the JAK2 , CALR , or MPL gene, and these clones generally...
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Hyperosmotic sisomicin infusion: a mouse model for hearing loss
Losing either type of cochlear sensory hair cells leads to hearing impairment. Inner hair cells act as primary mechanoelectrical transducers, while...
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Sparse transformer with local and seasonal adaptation for multivariate time series forecasting
Transformers have achieved remarkable performance in multivariate time series(MTS) forecasting due to their capability to capture long-term...
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Experimental and numerical investigations on the bending capacity of cold-formed steel box headers
The study investigates the bending strength of tracks of box headers beyond AISI, which considers the capacity of individual channels alone. Both...
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Scalable parameterized quantum circuits classifier
As a generalized quantum machine learning model, parameterized quantum circuits (PQC) have been found to perform poorly in terms of classification...
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Numerical simulations on compression behaviors of the laminated shale based on the digital image technology and the discrete element method
As an unconventional reservoir sedimentary rock, shale contains a series of layers and various microstructures that lead to complex mechanical...
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Humic acid and grafting as sustainable agronomic practices for increased growth and secondary metabolism in cucumber subjected to salt stress
Salinity stress poses a significant treat to crop yields and product quality worldwide. Application of a humic acid bio stimulant and grafting onto...
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Saltwater intrusion and human health risks for coastal populations under 2050 climate scenarios
Populations consuming saline drinking water are at greater risk of high blood pressure and potentially other adverse health outcomes. We modelled...
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Evaluation of the teratogenic potency of bulk zinc oxide and its nanoparticles on embryos of the freshwater snail, Helisoma duryi
Bulk zinc oxide (ZnO-BPs) and its nanoparticles (ZnO-NPs) are frequently used in various products for humans. Helisoma duryi embryos can serve as...
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Flood risk assessment of the Garita River in the urban zone of San Luis Potosí City, by hydrodynamic modeling
Rapid and uncontrolled urban growth and land use changes in watersheds worldwide have led to increased surface runoff within metropolitan areas,...
