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Associations between different triglyceride glucose index-related obesity indices and periodontitis: results from NHANES 2009–2014
BackgroundThis study aimed to explore the associations between triglyceride glucose (TyG) index-related obesity indices and periodontitis within the...
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The clinical impact of estimating low-density lipoprotein cholesterol (LDL-C) using different equations in the general population
BackgroundLow-density lipoprotein cholesterol (LDL-C) is associated with atherosclerotic cardiovascular disease (ASCVD). Friedewald, Sampson, and...
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Non-O blood types are associated with a greater risk of large artery atherosclerosis stroke and dysregulation of cholesterol metabolism: an observational study
BackgroundPrevious research on ABO blood types and stroke has been controversial, predominantly suggesting heightened risk of stroke in non-O blood...
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Association between Parkinson’s disease and cardiovascular disease mortality: a prospective population-based study from NHANES
Background and aimConflicting results have been reported on the association between Parkinson's disease (PD) and cardiovascular disease (CVD)...
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Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and obstructive sleep apnea: a cross-sectional study from NHANES
BackgroundObstructive Sleep Apnea (OSA) is a widespread sleep disturbance linked to metabolic and cardiovascular conditions. The Non-High-Density...
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Evaluation of the ability of insulin resistance and lipid-related indices to predict the presence of NAFLD in obese adolescents
BackgroundNonalcoholic fatty liver disease (NAFLD) has become an important health issue in adolescents. Although several parameters and indices have...
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Role of plasma fatty acid in age-related macular degeneration: insights from a mendelian randomization analysis
BackgroundAn imbalance in lipid metabolism has been linked to the development of AMD, but the causal relationship between AMD and plasma fatty acids...
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Metagenomic and metabolomic analysis showing the adverse risk–benefit trade-off of the ketogenic diet
BackgroundKetogenic diets are increasingly popular for addressing obesity, but their impacts on the gut microbiota and metabolome remain unclear....
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Serum lipid metabolism characteristics and potential biomarkers in patients with unilateral sudden sensorineural hearing loss
BackgroundGlycerophospholipids (GPLs) are essential for cell membrane structure and function. Sphingomyelin and its metabolites regulate cell growth,...
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Unveiling the therapeutic promise: exploring Lysophosphatidic Acid (LPA) signaling in malignant bone tumors for novel cancer treatments
Malignant bone tumors, including primary bone cancer and metastatic bone tumors, are a significant clinical challenge due to their high frequency of...
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Association between triglyceride glucose index-related indices with gallstone disease among US adults
BackgroundTriglyceride glucose (TyG) index combined with obesity-related indicators [triglyceride glucose-body mass index (TyG-BMI), triglyceride...
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Unraveling the controversy between fasting and nonfasting lipid testing in a normal population: a systematic review and meta-analysis of 244,665 participants
BackgroundThe final decision to fast or not fast for routine lipid profile examination in a standard, healthy population is unclear. Whereas the...
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Sphingolipid changes in mouse brain and plasma after mild traumatic brain injury at the acute phases
BackgroundTraumatic brain injury (TBI) causes neuroinflammation and can lead to long-term neurological dysfunction, even in cases of mild TBI (mTBI)....
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Deciphering the lipid–cancer nexus: comprehensive Mendelian randomization analysis of the associations between lipid profiles and digestive system cancer susceptibility
BackgroundDigestive system cancers represent a significant global health challenge and are attributed to a combination of demographic and lifestyle...
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Nicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis
BackgroundNonalcoholic steatohepatitis (NASH) is a prevalent chronic liver condition. However, the potential therapeutic benefits and underlying...
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Gender-specific accuracy of lipid accumulation product index for the screening of metabolic syndrome in general adults: a meta-analysis and comparative analysis with other adiposity indicators
BackgroundLipid accumulation product (LAP) is a novel predictor index of central lipid accumulation associated with metabolic and cardiovascular...
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Sex differences in lipidomic and bile acid plasma profiles in patients with and without coronary artery disease
BackgroundLipids, including phospholipids and bile acids, exert various signaling effects and are thought to contribute to the development of...
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Association of serum uric acid with hypertriglyceridemia in children and adolescents: a cross-sectional study
BackgroundUric acid (UA), a liver-derived metabolite, is intimately tied to metabolic disorders. Although ample research underscores its connection...
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7-MEGA™ inhibits adipogenesis in 3T3-L1 adipocytes and suppresses obesity in high-fat-diet-induced obese C57BL/6 mice
BackgroundOverweight, often known as obesity, is the abnormal and excessive accumulation of fat that exposes the health of a person at risk by...
