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Consensus paper on the management of acute isolated vertigo in the emergency department
Acute vertigo is defined as the perception of movement of oneself or the surroundings in the absence of actual motion and it is a frequent cause for...
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Targeting DNA Damage Response Deficiency in Thoracic Cancers
Thoracic cancers comprise non-small cell lung cancers (NSCLCs), small cell lung cancers (SCLCs) and malignant pleural mesotheliomas (MPM)....
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LncRNA ZFAS1 regulates ATIC transcription and promotes the proliferation and migration of hepatocellular carcinoma through the PI3K/AKT signaling pathway
PurposeLong noncoding RNAs (lncRNAs) exert a significant influence on various cancer-related processes through their intricate interactions with...
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Novel Vpx virus-like particles to improve cytarabine treatment response against acute myeloid leukemia
Knowledge of the molecular pathogenesis of acute myeloid leukemia has advanced in recent years. Despite novel treatment options, acute myeloid...
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Healthcare costs and medical utilization patterns associated with painful and severe painful diabetic peripheral neuropathy
PurposePainful diabetic peripheral neuropathy (DPN) is a common complication in patients with diabetes. It is associated with a poor quality of life...
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Platelet-Rich Plasma for Knee and Hip Osteoarthritis Pain: A Sco** Review
Purpose of ReviewPlatelet-rich plasma (PRP) is an emerging biological intervention for osteoarthritis (OA), yet the outcomes remain uncertain. The...
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Development and validation of nomogram for predicting the risk of transferring to the ICU for children with influenza
ObjectiveDevelopment of a nomogram model for predicting the magnitude of risk of transferring hospitalized children with influenza to the ICU.
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COVID-19 severity, breakthrough infections and vaccine safety in young individuals with autoimmune diseases: insights from the COVAD study
Notwithstanding the wealth of literature on COVID-19, studies focusing on young adults with autoimmune diseases (AD) are lacking. To determine early...
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Bloodstream infections due to multi-drug resistant bacteria in the emergency department: prevalence, risk factors and outcomes—a retrospective observational study
Multidrug-resistant organisms (MDROs) are prevalent in patients admitted to the Emergency Department (ED) and increase the risk of inappropriate...
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Targeting CD73 limits tumor progression and enhances anti-tumor activity of anti-PD-1 therapy in intrahepatic cholangiocarcinoma
Background & aimsPatients with intrahepatic cholangiocarcinoma (iCCA) respond poorly to immune checkpoint blockades (ICBs). In this study, we aimed...
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LncRNA PITPNA-AS1 mediates the diagnostic potential of miR-129-5p in prostate cancer
BackgroundLncRNA has an effective value in many diseases, which has long been applied in the diagnosis, treatment and prognosis of prostate cancer....
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Uric acid to albumin ratio as a novel predictor for coronary slow flow phenomenon in patients with chronic coronary syndrome and non-obstructive coronary arteries
BackgroundThe plasma uric acid to albumin ratio (UAR) is considered as a novel indicator for Inflammation. However, the association between UAR and...
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Glucagon-like peptide-1 (GLP-1) receptor agonists for headache and pain disorders: a systematic review
BackgroundGlucagon-like peptide-1 (GLP-1) plays a crucial role in metabolic disorders by enhancing insulin secretion, inhibiting glucagon release,...
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Beneficial Effect of Pretreatment Hyperosmolality on Outcome in Severe Traumatic Brain Injury: Evidence from a South Korean Multicenter Registry and Propensity Score Matching Analysis
BackgroundHyperosmolar therapy has long been a cornerstone in managing increased intracranial pressure and improving outcomes in severe traumatic...
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Vitamin D Supplementation and the Incidence of Fractures in the Elderly Healthy Population: A Meta-analysis of Randomized Controlled Trials
IntroductionAlthough a well-established component of bone metabolism, the efficacy and safety of vitamin D supplementation for the prevention of...
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Multimodal training protocols on unstable rather than stable surfaces better improve dynamic balance ability in older adults
BackgroundThere has been growing interest in using unstable devices in training protocols. This study aimed to assess the effectiveness of two...
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Hepatocellular Carcinoma in Asia: Physician and Patient Perspectives on Surveillance, Diagnosis, and Treatment
PurposeIn several Asian countries, hepatocellular carcinoma (HCC) is a leading cause of cancer deaths. HCC risk factors in Asia differ from those...
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Assessing seropositivity of MMR antibodies in individuals aged 2–22: evaluating routine vaccination effectiveness after the 2003 mass campaign-a study from Iran’s National Measles Laboratory
Background and purposeThe seroprevalence of antibodies against measles, mumps, and rubella (MMR) was evaluated 17 years following a mass vaccination...
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Serum GM-CSF level is a predictor of treatment response to tocilizumab in rheumatoid arthritis patients: a prospective observational cohort study
BackgroundThe aim of this prospective observational cohort study was to unveil the predictors of treatment response to tocilizumab (TCZ) therapy in...