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Non-falciparum malaria infections in Uganda, does it matter? A review of the published literature
BackgroundPlasmodium falciparum is the dominant malaria species in the sub-Saharan Africa and the main cause of severe disease and death....
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The effect of single low-dose primaquine treatment for uncomplicated Plasmodium falciparum malaria on haemoglobin levels in Ethiopia: a longitudinal cohort study
BackgroundTo interrupt residual malaria transmission and achieve successful elimination of Plasmodium falciparum in low-transmission settings, the...
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Priming antibody responses to the fusion peptide in rhesus macaques
Immunodominance of antibodies targeting non-neutralizing epitopes and the high level of somatic hypermutation within germinal centers (GCs) required...
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Assessing ChatGPT’s theoretical knowledge and prescriptive accuracy in bacterial infections: a comparative study with infectious diseases residents and specialists
ObjectivesAdvancements in Artificial Intelligence(AI) have made platforms like ChatGPT increasingly relevant in medicine. This study assesses...
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Use of Cefiderocol in Adult Patients: Descriptive Analysis from a Prospective, Multicenter, Cohort Study
IntroductionCefiderocol is a siderophore cephalosporin showing activity against various carbapenem-resistant Gram-negative bacteria (CR-GNB). No data...
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Understanding the impact of COVID-19 on antibiotic use in Canadian primary care: a matched-cohort study using EMR data
BackgroundInappropriate or overuse of antibiotic prescribing in primary care highlights an opportunity for antimicrobial stewardship (AMS) programs...
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Gastric bezoars secondary to mixed infection with Sarcina ventriculi and G + bacilli: a case report
Sarcina ventriculi is a bacterium with a specific histological morphology and infection can present with symptoms such as abdominal pain, nausea,...
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Analyzing the molecular mechanism of Scutellaria Radix in the treatment of sepsis using RNA sequencing
BackgroundSepsis is a life-threatening organ dysfunction, which seriously threatens human health. The clinical and experimental results have...
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An evidence-based screening tool for heart failure with preserved ejection fraction: the HFpEF-ABA score
Heart failure with preserved ejection fraction (HFpEF) is under-recognized in clinical practice. Although a previously developed risk score, termed H 2 ...
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Hippocampal network activity forecasts epileptic seizures
Seizures in people with epilepsy were long thought to occur at random, but recent methods for seizure forecasting enable estimation of the likelihood...
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Hel** Others Facilitates Well-Being for Indigenous Peoples Living With HIV/AIDS in Canada
Research has found that hel** others facilitates well-being for Indigenous peoples living with HIV and AIDS, but limited research exists that...
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Selective depletion of Campylobacter jejuni via T6SS dependent functionality: an approach for improving chickens gut health
The targeted depletion of potential gut pathogens is often challenging because of their intrinsic ability to thrive in harsh gut environments....
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An adult with hemorrhagic varicella co-infects with cytomegalovirus: a case report
BackgroundHemorrhagic varicella (HV) is a particular form of chicken pox.,with high mortality in adults. This form of the disease is rare, to date,...
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Staphylococcus aureus screening and preoperative decolonisation with Mupirocin and Chlorhexidine to reduce the risk of surgical site infections in orthopaedic surgery: a pre-post study
BackgroundNasal carriage of Staphylococcus aureus is a risk factor for surgical site infections (SSI) in orthopaedic surgery. The efficacy of...
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Gastrointestinal Manifestation of MPox
Purpose of ReviewMpox, formerly known as monkeypox, is a zoonotic illness caused by a virus that is part of the Orthopoxvirus family. Originally...
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Benmelstobart, anlotinib and chemotherapy in extensive-stage small-cell lung cancer: a randomized phase 3 trial
Immunochemotherapy is the first-line standard for extensive-stage small-cell lung cancer (ES-SCLC). Combining the regimen with anti-angiogenesis may...
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Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results
Adoptive cell transfer (ACT) with neoantigen-reactive T lymphocytes can mediate cancer regression. Here we isolated unique, personalized,...
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Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition
Current cardiometabolic disease prevention guidelines recommend increasing dietary unsaturated fat intake while reducing saturated fats. Here we use...
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Ensuring People Living with HIV Inform the Future of HIV Treatment in Low- and Middle-Income Countries: A Sco** Review and Recommendations for a Community-Led Research Agenda
The HIV treatment landscape in low- and middle-income countries (LMICs) is rapidly evolving, exemplified by the expansion of differentiated service...
