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Development of Technetium-99m and Rhenium-188 Radiopharmaceuticals Containing a Terminal Metal–Nitrido Multiple Bond for Diagnosis and Therapy
The chemistry of nitrido complexes of technetium has played an important role in the search of new Tc-99m radiopharmaceuticals and in providing... -
Monitoring Multidrug Resistance P-Glycoprotein Drug Transport Activity with Single-Photon Emission Computed Tomography and Positron Emission Tomography Radiopharmaceuticals
Multidrug resistance (MDR) mediated by overexpression of MDR1 P-glycoprotein (Pgp) is one of the best characterized transporter-mediated barriers to... -
Radiopharmaceuticals for Positron Emission Tomography Imaging of Somatostatin Receptor Positive Tumors
The targeting of somatostatin receptors in tumors has been a goal in cancer treatment and diagnosis since the 1980s. Over the past two decades, great... -
Rhenium and Technetium Complexes Anchored by Phosphines and Scorpionates for Radiopharmaceutical Applications
This review presents a comprehensive overview of the most significant developments in the chemistry of technetium and rhenium complexes anchored by... -
Radiolabeled Integrin αvβ3 Antagonists as Radiopharmaceuticals for Tumor Radiotherapy
Integrins are a family of proteins that facilitate cellular adhesion to and migration on the extracellular matrix proteins found in intercellular... -
6-Hydrazinonicotinamide Derivatives as Bifunctional Coupling Agents for 99mTc-Labeling of Small Biomolecules
99mTc-labeled small biomolecules are a class of receptor-based, target specific radiopharmaceuticals for the detection of various diseases, such as... -
New Organometallic Technetium Complexes for Radiopharmaceutical Imaging
It is the objective of this review to introduce the reader to the current status of organometallic chemistry, oriented towards the development of... -
Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...
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Prediction of microvascular invasion in hepatocellular carcinoma patients with MRI radiomics based on susceptibility weighted imaging and T2-weighted imaging
BackgroundThe accurate identification of microvascular invasion (MVI) in patients with hepatocellular carcinoma (HCC) is of great clinical importance.
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Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey
PurposeThis study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...
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Mindfulness in Orthopedic Rehabilitation: Can the Use of a Mindfulness Diary Positively Influence the Therapeutic Outcome of Orthopedic Rehabilitation?
ObjectivesMindfulness is a proven therapeutic practice for reducing anxiety, depression, and chronic pain, which are factors that influence the...
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A scarce combination of arterial variants: an occipital artery originating from the internal carotid artery associated with a linguofacial trunk
The occipital artery (OA) typically originates from the external carotid artery (ECA). Variations of the ECA has been well described in the current...
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Safety and Efficacy of Covered Self-Expandable Metallic Stent for Choledochojejunal Anastomotic Stricture: A Multi-Center Retrospective Cohort Study
BackgroundBenign choledochojejunal anastomotic stricture (CJS) is a complication of pancreaticoduodenectomy and choledochojejunostomy. Typically...
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Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study
PurposeNeoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response...
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Impact and effect of imaging referral guidelines on patients and radiology services: a systematic review
ObjectivesThe objective of this systematic review was to offer a comprehensive overview and explore the associated outcomes from imaging referral...
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Neuroprotective and vasoprotective effects of herb pair of Zhiqiao-Danggui in ischemic stroke uncovered by LC-MS/MS-based metabolomics approach
Ischemic stroke is the most important cause of disability and death worldwide, but current treatments remain limited. Traditional Chinese medicine...
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Buprenorphine vs. morphine: impact on neonatal opioid withdrawal syndrome (NOWS) outcomes in a single center retrospective study
ObjectivesTo compare clinical outcomes for infants with neonatal opioid withdrawal syndrome (NOWS) treated with buprenorphine or morphine.
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Stability and Validity of Self-Reported Depression and Anxiety in Autistic Youth
The aim of this study was to assess test-retest reliability and diagnostic validity of self-report instruments of depression and anxiety in autistic...
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Association Between Physical Activity, Sedentary Time, and Technology Use in Autistic Adults
There is little understanding of physical activity (PA) and sedentary behavior as preventive health behaviors in autistic adults. Technology has been...