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Development and validation of extraction and clean-up procedures for UPLC-MS/MS analysis of aflatoxins in spices
UPLC-MS/MS analytical conditions for the analysis of aflatoxins in spices were optimized and validated in this study. Liquid-liquid partition-based...
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Impact of baseline body composition on prognostic outcomes in urological malignancies treated with immunotherapy: a pooled analysis of 10 retrospective studies
ObjectiveNumerous epidemiological investigations have explored the impact of body composition on the effectiveness of immune checkpoint inhibitors...
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African American Female Veterans Experiences with Perceived Racism Within the Veteran’s Healthcare Administration
There is a lack of understanding of how perceived racism in Veterans Healthcare Administration (VHA) healthcare providers affects the delivery of...
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Gut Microbiome and colorectal cancer: discovery of bacterial changes with metagenomics application in Turkısh population
BackgroundColorectal cancer (CRC) is the 3rd most common cancer in the world and colonic carcinogenesis is a multifactorial disease that involves...
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Actn2 defects accelerates H9c2 hypertrophy via ERK phosphorylation under chronic stress
BackgroundIn humans, ACTN2 mutations are identified as highly relevant to a range of cardiomyopathies such as DCM and HCM, while their association...
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Electroacupuncture Alleviates Memory Deficits in APP/PS1 Mice by Targeting Serotonergic Neurons in Dorsal Raphe Nucleus
ObjectiveAlzheimer’s disease (AD) has become a significant global concern, but effective drugs able to slow down AD progression is still lacked....
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Sedentary behavior is associated with the mental health of university students during the Covid-19 pandemic, and not practicing physical activity accentuates its adverse effects: cross-sectional study
BackgroundMovement behaviours, such as sedentary behavior (SB) and physical inactivity, have become a public health issue due to their implications...
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An initial user model design for adaptive interface development in learning management system based on cognitive load
The cognitive aspect is crucial in develo** interactive and adaptive systems, including learning management systems (LMS). By understanding human...
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Biological Evaluation of Lysionotin: a Novel Inhibitor of 5-Lipoxygenase for Anti-glioma
ObjectiveTo explore the potential mechanism of lysionotin in treating glioma.
MethodsFirst, target prediction based on Bernoulli Naïve Bayes...
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Diagnosis, treatment and management of lipodystrophy: the physician perspective on the patient journey
BackgroundLipodystrophy syndromes are a heterogeneous group of rare, life-limiting diseases characterized by a selective loss of adipose tissue and...
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Identification of risk factors of Long COVID and predictive modeling in the RECOVER EHR cohorts
BackgroundSARS-CoV-2-infected patients may develop new conditions in the period after the acute infection. These conditions, the post-acute sequelae...
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Maternal distress, parenting stress, maladaptive parenting and children’s problematic media use in China: evidence from 2022 spring in Shanghai
The COVID-19 lockdown has forced young children to spend more time on media and significantly impacted their mothers’ mental health. This study...
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Insights from an N3C RECOVER EHR-based cohort study characterizing SARS-CoV-2 reinfections and Long COVID
BackgroundAlthough the COVID-19 pandemic has persisted for over 3 years, reinfections with SARS-CoV-2 are not well understood. We aim to characterize...
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A new approach to prevent radiation-induced xerostomia using intraglandular injection of mitochondria-boosting agents
Radiotherapy in patients with head and neck cancer fairly leads to xerostomia, profoundly affecting their quality of life. With limited effective...
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The ANGPTL4-HIF-1α loop: a critical regulator of renal interstitial fibrosis
BackgroundRenal interstitial fibrosis (RIF) is a progressive, irreversible terminal kidney disease with a poor prognosis and high mortality....
