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  1. The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice

    Background

    This study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk...

    Dong Xu, Lin Sui, ... Li** Wang in BMC Medicine
    Article Open access 12 July 2024
  2. Mesomelia-synostoses syndrome: contiguous deletion syndrome, SULF1 haploinsufficiency or enhancer adoption?

    Background

    Mesomelia-Synostoses Syndrome (MSS)(OMIM 600,383) is a rare autosomal dominant disorder characterized by mesomelic limb shortening, acral...

    Ingrid Bendas Feres Lima, Lúcia de Fátima Marques de Moraes, ... Elenice Ferreira Bastos in Molecular Cytogenetics
    Article Open access 12 July 2024
  3. Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases

    Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells. Whether...

    Zhan-Li Chen, Chen **e, ... Shi-Mei Zhuang in Signal Transduction and Targeted Therapy
    Article Open access 12 July 2024
  4. Hemophagocytic Lymphohistiocytosis for the Inpatient Dermatologist

    Hemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening condition characterized by dysregulation of the immune system leading to...

    Bliss Colao, Grace Hingtgen, ... Kiran Motaparthi in Current Dermatology Reports
    Article 12 July 2024
  5. Diagnostic performance of coronary calcifications on CT to rule out acute coronary syndrome in the emergency department

    Background

    At present, the diagnosis of acute coronary syndrome (ACS) can be made by emergency physicians using the usual complementary tests, since...

    Julie Paget Sentagne, Mickaël Ohana, ... Sabrina Kepka in BMC Emergency Medicine
    Article Open access 12 July 2024
  6. Fragile X Syndrome and FMR1 premutation: results from a survey on associated conditions and treatment priorities in Italy

    Background and objectives

    Fragile X Syndrome (FXS) is the most common cause of inherited intellectual disability, caused by CGG-repeat expansions...

    Federica Alice Maria Montanaro, Paolo Alfieri, ... Stefano Vicari in Orphanet Journal of Rare Diseases
    Article Open access 12 July 2024
  7. Effect of dipeptidyl peptidase-4 inhibitors on tumor necrosis factor alpha levels in patients with type 2 diabetes mellitus

    Aims

    Dipeptidyl peptidase-4 inhibitors (DPP-4i) served as oral antidiabetic agents for treatment of type 2 diabetes mellitus (T2DM). Although an...

    Lijia Zhao, Jie Meng, ... **n Liu in European Journal of Medical Research
    Article Open access 12 July 2024
  8. Real world treatment outcomes in polypoidal choroidal vasculopathy in a Caucasian population of British ethnicity

    Purpose

    To assess treatment response of Polypoidal choroidal vasculopathy (PCV) in a Caucasian population of British ethnicity with intravitreal...

    Gabriella De Salvo, Suresh Thulasidharan, ... Rino Frisina in Eye
    Article 12 July 2024
  9. Sodium tanshinone IIA sulfonate protects vascular relaxation in ApoE-knockout mice by inhibiting the SYK-NLRP3 inflammasome-MMP2/9 pathway

    Background

    Hyperlipidemia damages vascular wall and serves as a foundation for diseases such as atherosclerosis, hypertension and stiffness. The...

    Hai-Hua Liu, Wei Wei, ... Peng-Fei Zhang in BMC Cardiovascular Disorders
    Article Open access 12 July 2024
  10. Hydrogels for Musculoskeletal Tissue Engineering

    The advancements in scaffold-supported cell therapy for musculoskeletal tissue engineering have been truly dramatic in the last couple of decades....
    Shyni Varghese, Jennifer H. Elisseeff in Polymers for Regenerative Medicine
    Chapter
  11. Virtual Reality in Healthcare

    In our modern 21st century, daily life would be unthinkable without computers. Multimedia and virtual reality are useful for people with special...
    Chapter
  12. Access to Information on Demand by the aid of Digital Talking Books

    This chapter addresses the concept and the fundamental ideas of the digital talking book (DTB), with a particular focus on DTBs in the DAISY format....
    Thomas Kjellberg Christensen, Margit Dühring in Intelligent Paradigms for Assistive and Preventive Healthcare
    Chapter
  13. Exploring paramedics’ lived experiences in confrontation with patients’ death during missions: a phenomenological study

    Background

    Emergency personnel are the first line of emergency response systems to respond to emergencies; in essence, they are usually exposed to a...

    Milad Ahmadi Marzaleh, Mahmoudreza Peyravi, ... Hossein Avazaghaei in BMC Emergency Medicine
    Article Open access 12 July 2024
  14. Improving the introduction of telemedicine in pre-hospital emergency medicine: understanding users and how acceptability, usability and effectiveness influence this process

    Introduction

    Increasing numbers of ambulance calls, vacant positions and growing workloads in Emergency Medicine (EM) are increasing the pressure to...

    Seán O’Sullivan, Jennifer Krautwald, Henning Schneider in BMC Emergency Medicine
    Article Open access 12 July 2024
  15. Mucinous tubular and spindle renal cell carcinoma revealed by a trauma of the kidney: a case report

    Background

    Mucinous tubular and spindle cell carcinoma is a rare renal tumor. It has been recognized as a distinct entity in the 2004 World Health...

    Kays Chaker, Mahdi Marrak, ... Yassine Nouira in Journal of Medical Case Reports
    Article Open access 12 July 2024
  16. Contribution of plasma levels of VEGF-A and angiopoietin-2 in addition to a genetic variant in KCNAB1 to predict the risk of bevacizumab-induced hypertension

    Bevacizumab-induced hypertension poses a therapeutic challenge and identifying biomarkers for hypertension can enhance therapy safety. Lower plasma...

    Julia C. F. Quintanilha, William Kevin Kelly, Federico Innocenti in The Pharmacogenomics Journal
    Article 12 July 2024
  17. Non-emergency department (ED) interventions to reduce ED utilization: a sco** review

    Background

    Emergency department (ED) crowding is a global burden. Interventions to reduce ED utilization have been widely discussed in the literature,...

    Målfrid A. Nummedal, Sarah King, ... Lars Petter Bjørnsen in BMC Emergency Medicine
    Article Open access 12 July 2024
  18. Woven coronary artery with acquired etiology: the natural history documented by serial angiography and optical coherence tomography

    Woven coronary artery (WCA) is a rare anomaly and its etiology remains speculative. Both congenital and acquired factors are considered to be...

    Jiannan Li, **aoli Wang, ... Hanjun Zhao in BMC Cardiovascular Disorders
    Article Open access 12 July 2024
  19. Exploring the inverse relationship between serum total bilirubin and systemic immune-inflammation index: insights from NHANES data (2009–2018)

    Background

    Bilirubin is known for its multifaceted attributes, including antioxidant, anti-inflammatory, immunomodulatory, and antiapoptotic...

    Shan-Shan Huang, Yi Ding, ... Zhou-**n Yang in European Journal of Medical Research
    Article Open access 12 July 2024
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