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Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...
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Doing a double take: when transthoracic echocardiography fails for mitral valve annuloplasty ring endocarditis with Streptococcus pyogenes: a case report
BackgroundThis case highlights several complications of a late and rare presentation of culture-negative Streptococcus pyogenes endocarditis of a...
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Social costs associated with fibromyalgia in Spain
BackgroundFibromyalgia is a chronic rheumatic disease of unknown aetiology, highly disabling and mainly affecting women. The aim of our work is to...
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Multiple lung abscesses and cold agglutinin syndrome following coronavirus disease 2019: a case report
BackgroundCold agglutination syndrome is a subtype of autoimmune hemolytic anemia. The condition is referred to as “cold” because the antibodies...
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Re-territorialising skills? Insights from ethnography on solidarity-economy food activism
The article addresses the role of citizens in setting up short food chains in the framework of the solidarity economy movement in Lombardy, Italy. On...
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To Improve Motivational Barriers to Retention in High Resolution Anoscopy, Patients and Providers Recommend Social and Environmental Changes: A Sequential Explanatory Mixed-Methods Pilot Study in a Federally Qualified Health Center
Loss to follow-up (LTFU) in high-resolution anoscopy (HRA) programs jeopardizes the procedure’s potential to help prevent anal cancer. We explored...
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Use of Cost-Effectiveness Thresholds in Healthcare Public Policy: Progress and Challenges
The article offers a comparative analysis of the influence of cost-effectiveness thresholds in the decision-making processes in financing policies,...
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The Evolution of Symbolic Thought: At the Intersection of Schizophrenia Psychopathology, Ethnoarchaeology, and Neuroscience
The human capacity for symbolic representation arises, evolutionarily and developmentally, from the exploitation of a widespread sensorimotor...
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Food-based domestic violence and anemia among women in sexual unions in Nigeria: the effect of urbanization
In 2019, 1.74 billion people worldwide had anemia. In Nigeria, women of reproductive age are the most affected. Domestic violence affects the anemia...
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Associations between the choroid plexus and tau in Alzheimer’s disease using an active learning segmentation pipeline
BackgroundThe cerebrospinal fluid (CSF), primarily generated by the choroid plexus (ChP), is the major carrier of the glymphatic system. The...
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Caregiver-Youth Communication Patterns and Sexual and Reproductive Health Among American Indian Youth
Improving communication between American Indian caregivers and their youth has been suggested as an Indigenous-forward strategy to help alleviate the...
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Revolutionising health and social care: innovative solutions for a brighter tomorrow – a systematic review of the literature
BackgroundIn an era marked by rapid technological advancements, changing demographics, and evolving healthcare needs, the landscape of health...
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Disparities in satisfaction among insured and uninsured adult outpatient department service users in Southern Ethiopia, 2022: a comparative cross-sectional study
BackgroundPatient satisfaction is a critical measure of the quality of healthcare services provided by healthcare facilities. However, very few...
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A retrospective cohort study to evaluate disease burden, health care resource utilization, and costs in patients with breast cancer in Dubai, UAE
BackgroundThe current study evaluated the disease burden, health care resource utilization and analyzed the cost burden due to events of special...
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Outcomes of deep venous thrombosis management and associated factors among patients in tertiary hospitals in Addis Ababa, Ethiopia: a multicenter retrospective cohort study
BackgroundPulmonary embolism (PE) and deep venous thrombosis (DVT) are the two most important manifestations of venous thromboembolism (VTE). DVT...
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Nuclear alpha-synuclein accelerates cell senescence and neurodegeneration
BackgroundThe progression of Parkinson’s disease (PD) is related to ageing. The accumulation of nuclear alpha-synuclein (α-syn) may accelerate the...
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Brief Report: Relationships Between Caregiver-Reported Externalizing and Internalizing Behaviors and the Modified Checklist for Autism in Toddlers
PurposeEarly detection and intervention are associated with improved outcomes for autistic children. Thus, it is important to understand factors...
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Intake Characteristics as Predictors of Psychotherapy Outcome in a Practice Research Network in Argentina
There are few studies exploring intake diagnostic characteristics as predictors of change in integrative naturalistic settings. The aim of this study...
