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  2. Advanced Targeting Strategies for Murine Retroviral and Adeno-associated Viral Vectors

    Targeted gene delivery involves broadening viral tropism to infect previously nonpermissive cells, replacing viral tropism to infect a target cell...
    Julie H. Yu, David V. Schaffer in Gene Therapy and Gene Delivery Systems
    Chapter

  3. Nonviral Delivery of Cancer Genetic Vaccines

    The potential use of genetic vaccines to address numerous diseases including cancer is promising, but currently unrealized. Here, we review...
    Steven R. Little, Robert Langer in Gene Therapy and Gene Delivery Systems
    Chapter

  4. Production and Formulation of Adenovirus Vectors

    Adenovirus vectors have attracted considerable interest over the past decade, with ongoing clinical development programs for applications ranging...
    Nedim E. Altaras, John G. Aunins, ... Jayanthi J. Wolf in Gene Therapy and Gene Delivery Systems
    Chapter

  5. Molecular Conjugates

    Molecular conjugates are nanometer-sized entities consisting of synthetic materials (lipids, polycations, targeting agents, and so on) and nucleic...
    Jeremy Heidel, Swaroop Mishra, Mark E. Davis in Gene Therapy and Gene Delivery Systems
    Chapter

  6. Adeno-associated Virus as a Gene Therapy Vector: Vector Development, Production and Clinical Applications

    Adeno-associated virus (AAV) has emerged as an attractive vector for gene therapy. AAV vectors have successfully been utilized to promote...
    Joshua C. Grieger, Richard J. Samulski in Gene Therapy and Gene Delivery Systems
    Chapter

  7. Lentiviral Vectors

    We review the use of lentiviral vectors in current human gene therapy applications that involve genetic modification of nondividing tissues with...
    Nils Loewen, Eric M. Poeschla in Gene Therapy and Gene Delivery Systems
    Chapter

  8. Plasmid Vaccines and Therapeutics: From Design to Applications

    In the late 1980s, Vical and collaborators discovered that the injection into tissues of unformulated plasmid encoding various proteins resulted in...
    Marston Manthorpe, Peter Hobart, ... Alain Rolland in Gene Therapy and Gene Delivery Systems
    Chapter

  10. Exploring the capabilities of ChatGPT in women’s health: obstetrics and gynaecology

    Artificial Intelligence (AI) is transforming healthcare, with Large Language Models (LLMs) like ChatGPT offering novel capabilities. This study...

    Magdalena Bachmann, Ioana Duta, ... Gabriel Davis Jones in npj Women's Health
    Article Open access 15 July 2024

  11. 3Dimensional sonography for the diagnosis of congenital uterine anomalies in women with eccentric pregnancy implantation: a novel approach

    Purpose

    The eccentric implantation of pregnancies in the upper lateral aspect of the uterine cavity is poorly defined clinically. The aim of the...

    Yaakov Melcer, Perry Eliassi Revivo, ... Ron Maymon in Archives of Gynecology and Obstetrics
    Article 15 July 2024

  14. Short-term S100A8/A9 Blockade Promotes Cardiac Neovascularization after Myocardial Infarction

    Acute-phase inhibition of the pro-inflammatory alarmin S100A8/A9 improves cardiac function post-myocardial infarction (MI), but the mechanisms...

    Razvan Gheorghita Mares, Viorel Iulian Suica, ... Alexandru Schiopu in Journal of Cardiovascular Translational Research
    Article Open access 15 July 2024

  15. Editorial

    in best practice onkologie
    Article 15 July 2024

  16. Readability of online patient education material for foregut surgery

    Introduction

    Health literacy is the ability of individuals to use basic health information and services to make well-informed decisions. Low health...

    Michelle Chang, Barry Weiss, ... Iman Ghaderi in Surgical Endoscopy
    Article 15 July 2024

  17. Comprehensive and deep evaluation of structural variation detection pipelines with third-generation sequencing data

    Background

    Structural variation (SV) detection methods using third-generation sequencing data are widely employed, yet accurately detecting SVs...

    Zhi Liu, Zhi **e, Miaoxin Li in Genome Biology
    Article Open access 15 July 2024

  18. Coronary periarteritis and pericarditis are rare but distinct manifestations of heart involvement in IgG4-related disease: a retrospective cohort study

    Background

    The heart can be involved in immunoglobulin (Ig)-G4-related disease (IgG4-RD). This study aimed to summarize the clinical features and...

    Tianrui Hua, Juan Du, ... Wen Zhang in Orphanet Journal of Rare Diseases
    Article Open access 15 July 2024

  19. A Hybrid Form of Telemedicine and Quality Improvement: A Unique Way to Extend Intensive Care Services to Neonates

    Objectives

    To evaluate the impact of hybrid support (tele-mentoring and conventional support) on adverse outcome among neonates admitted to 10 special...

    Nikita Agarwal, Rohit Anand, ... Gajendra Singh in Indian Journal of Pediatrics
    Article 15 July 2024

  20. Association between dietary insulin index and postmenopausal osteoporosis in Iranian women: a case-control study

    Background

    The relationship between the dietary insulin index (DII) and the disease’s risk is unknown, despite the fact that hyperinsulinemia is...

    Shakiba Solgi, Farid Zayeri, Behnood Abbasi in BMC Women's Health
    Article Open access 15 July 2024
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