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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive...
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Emodin alleviates intestinal ischemia–reperfusion injury through antioxidant stress, anti-inflammatory responses and anti-apoptosis effects via Akt-mediated HO-1 upregulation
BackgroundIntestinal ischemia–reperfusion (I/R) injury is a severe vascular emergency. Previous research indicated the protective effects of Emodin...
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Effect of changes in motor skill induced by educational video program to decrease lower-limb joint load during cutting maneuvers: based on musculoskeletal modeling
BackgroundThis study investigated the effects of changes in motor skills from an educational video program on the kinematic and kinetic variables of...
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Association between carpal height ratio and ulnar variance in normal wrist radiography
IntroductionThe wrist joint is a complex anatomical structure, and various radiographic parameters are utilized to assess its normal alignment and...
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The association between the neutrophil-to-lymphocyte ratio and type 2 diabetes mellitus: a cross-sectional study
BackgroundType 2 diabetes mellitus (T2DM) is a prevalent chronic disease often accompanied by low-grade inflammation. Recently, the...
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The incidence of fractures in children under two years of age: a systematic review
BackgroundEpidemiological research on fractures in children under the age of two is of great importance to help understand differences between...
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New studies with stable gastric pentadecapeptide protecting gastrointestinal tract. significance of counteraction of vascular and multiorgan failure of occlusion/occlusion-like syndrome in cytoprotection/organoprotection
Since the early 1990s, when Robert’s and Szabo’s cytoprotection concept had already been more than one decade old, but still not implemented in...
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Schmerztherapie in der Rheumatologie
Treatment of painful rheumatic diseases encompasses nonpharmacologic and pharmacologic measures. Pain of short duration usually responds well to...
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CYP24A1 Deficiency Mimicking Other Causes of Hypercalciuria and Nephrocalcinosis: A Case Report
In this report, we discuss the case of a 54-year-old patient attending our department with osteopenia, urolithiasis, significant hypercalciuria, and...
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Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT/FoxO1 and PI3K/AKT/mTOR Signalling Pathways
Methylprednisolone (MP) is a potent glucocorticoid that can effectively inhibit immune system inflammation and brain tissue damage in Multiple...
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Efficacy of tibial cortex transverse transport in treating diabetic foot ulcer and its effect on serum omentin-1 and irisin levels
ObjectiveDiabetic foot ulcer (DFU) is a common and debilitating complication of diabetes that is associated with an increased risk of lower-limb...
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Evaluation of fragility fracture risk using deep learning based on ultrasound radio frequency signal
BackgroundIt was essential to identify individuals at high risk of fragility fracture and prevented them due to the significant morbidity, mortality,...
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Effect of switching from twice-daily basal insulin to once-daily insulin glargine 300 U/mL (Gla-300) in Brazilian people with type 1 diabetes
BackgroundLow adherence to the number of insulin injections and glycemic variability are among the challenges of insulin therapy in type 1 diabetes...
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Association between bone turnover markers, bone mineral density, and serum osteoglycine in middle-aged men with Type 2 Diabetes mellitus
BackgroundPatients with Type 2 diabetes mellitus (T2DM) have decreased bone health. We aimed to investigate serum levels of bone turnover markers...
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The correlation between hepatic controlled attenuation parameter (CAP) value and insulin resistance (IR) was stronger than that between body mass index, visceral fat area and IR
BackgroundHepatic controlled attenuation parameter (CAP) is a novel marker for quantifying hepatic fat accumulation. Insulin resistance (IR) plays a...
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Challenges in the management of patients with HNF1B MODY and multisystem manifestations: the cases of two adolescent boys
IntroductionHepatocyte nuclear factor-1 beta ( HNF1B ) encodes a homeodomain-containing transcription factor, which is expressed early in...
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INFLA score: a novel inflammatory marker for assessing cardiometabolic disease risk in obese individuals
BackgroundThe low-grade inflammation score (INFLA-score) is a composite index that assesses chronic inflammatory status using multiple inflammatory...
