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Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...
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PET imaging of neuroinflammation: any credible alternatives to TSPO yet?
Over the last decades, the role of neuroinflammation in neuropsychiatric conditions has attracted an exponentially growing interest. A key driver for...
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Hydrogels for Musculoskeletal Tissue Engineering
The advancements in scaffold-supported cell therapy for musculoskeletal tissue engineering have been truly dramatic in the last couple of decades....
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Virtual Reality in Healthcare
In our modern 21st century, daily life would be unthinkable without computers. Multimedia and virtual reality are useful for people with special...
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Access to Information on Demand by the aid of Digital Talking Books
This chapter addresses the concept and the fundamental ideas of the digital talking book (DTB), with a particular focus on DTBs in the DAISY format....
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Multimedia Communication System for the Blind
A Multimedia communication system for blind users is developed. The system is named MIMIZU and its terminal is composed of a refreshable tactile...
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Gait Training System for Computer-aided Rehabilitation
This Gait Training system is designed to simulate the effects of gait training in a swimming pool. The weight of the subject is supported by a...
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Electronic Locomotion Aids for the Blind: Towards More Assistive Systems
This chapter first presents a review of existing locomotion assistance devices for the blind. These devices are merely proximeters, that measure the...
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Polymeric Systems for Bioinspired Delivery of Angiogenic Molecules
Growth factors are increasingly utilized to promote regeneration of lost or compromised tissues and organs. However, current strategies applying...
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Biopolyesters in Tissue Engineering Applications
Tissue engineering is a rapidly growing interdisciplinary field of research focused on the development of vital autologous tissue through the use...
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Interfaces to Control Cell-Biomaterial Adhesive Interactions
Cell adhesion to adsorbed proteins and adhesive sequences engineered on surfaces is crucial to cellular and host responses to implanted devices,...
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Ubiquitous Healthcare: Technology and Service
Ubiquitous healthcare is introduced in terms of technology and service, considering the current technology as well as the future technology and...
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Information Technology for Deaf People
In our modern information and communication society, daily life would be unthinkable without technology. Information and Communications Technology...
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Multimedia Medical Informatics System in Healthcare
In our modern 21st century, daily life would be unthinkable without computers. Multimedia and virtual reality are useful for people with spein...
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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive...
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Self-Assembling Nanopeptides Become a New Type of Biomaterial
Combining physics, engineering, chemistry and biology, we can now design, synthesize and fabricate biological nano-materials at the molecular...
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Modulating Extracellular Matrix at Interfaces of Polymeric Materials
As extracellular matrices (ECM) closely interact with cells in living tissues and, through this, influence essentially any aspect of life...
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The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice
BackgroundThis study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk...
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Real world treatment outcomes in polypoidal choroidal vasculopathy in a Caucasian population of British ethnicity
PurposeTo assess treatment response of Polypoidal choroidal vasculopathy (PCV) in a Caucasian population of British ethnicity with intravitreal...
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Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases
Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells. Whether...
