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Absence of effects of widespread badger culling on tuberculosis in cattle
Government policy in England aims for the elimination of bovine tuberculosis (bTB). This policy includes culling of European badger ( Meles meles ) to...
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\(\text{Sech}^{2}\)-type solitary waves and the stability analysis for the KdV–mKdV equation
In this article, we investigated the solitary wave solutions of the KdV–mKdV equation using Hirota’s bilinear method. Closed-form analytical single...
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Phylogeography and genetic structure of Papaver bracteatum populations in Iran based on genoty**-by-sequencing (GBS)
Papaver bracteatum , known for its high thebaine content and absence of morphine, has emerged as a promising alternative to opium poppy for codeine...
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The regulatory mechanism of m6A modification in gastric cancer
To the best of our knowledge, N6-Methyladenosine (m6A) exerts a significant role in the occurrence and development of various tumors. Gastric cancer...
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Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging
Intrinsic and extrinsic factors, including lifestyle and sun exposure, can contribute to cell senescence, which impairs skin homeostasis, that may in...
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Comparison of four confirmatory tests for the diagnosis of primary aldosteronism: Bayesian analysis in the absence of a gold standard
BackgroundCaptopril challenge test (CCT), seated saline infusion test (SSIT), oral sodium loading test (OSLT) and fludrocortisone suppression test...
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The neural representation of stereotype content
Judgments about social groups are characterized by their position in a representational space defined by two axes, warmth and competence. We examined...
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Inositols and female reproduction disorders: a consensus statement from the working group of the Club of the Italian Society of Endocrinology (SIE)—Women’s Endocrinology
PurposeTo provide the latest scientific knowledge on the efficacy of inositols for improving reproductive disorders in women with and without...
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Effect of caspase inhibitors on hemodynamics and inflammatory factors in ARDS model rats
To study the effects of caspase inhibitors on hemodynamics and inflammatory factors in acute respiratory distress syndrome (ARDS) model rats. Sixty...
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The multifaceted role of PCSK9 in cancer pathogenesis, tumor immunity, and immunotherapy
Proprotein convertase subtilisin/kexin type 9 (PCSK9), a well-known regulator of cholesterol metabolism and cardiovascular diseases, has recently...
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The occurrence and human health risk assessment of total and aflatoxin B1 in selected food commodities in Bhutan
Aflatoxins are mycotoxins that contaminate staple foods globally and pose a significant health risk. To the best of our knowledge, information on the...
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Adherence and persistence to tafamidis treatment among Medicare beneficiaries in the presence of a patient assistance program
Tafamidis is the only disease-modifying therapy approved to treat patients in the United States with transthyretin amyloid cardiomyopathy (ATTR-CM),...
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Fractional order cancer model infection in human with CD8+ T cells and anti-PD-L1 therapy: simulations and control strategy
In order to comprehend the dynamics of disease propagation within a society, mathematical formulations are essential. The purpose of this work is to...
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Assessment of heat stress contributing factors in the indoor environment among vulnerable populations in Klang Valley using principal component analysis (PCA)
Rising global temperatures can lead to heat waves, which in turn can pose health risks to the community. However, a notable gap remains in...
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Early colonic-preparation and salvage laparoscopic appendectomy (ECSLA)- innovative protocol for the management of magnets ingestion
BackgroundIngestion of magnets carries risks for significant morbidity. We propose a new protocol designed to reduce the need for surgery, shorten...
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A buzzword, a “win-win”, or a signal towards the future of agriculture? A critical analysis of regenerative agriculture
As the term regenerative agriculture caught fire in public discourse around 2019, it was promptly labelled a buzzword. While the buzzword accusation...
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Single-cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape
How disruptions to normal cell differentiation link to tumorigenesis remains incompletely understood. Wilms tumor, an embryonal tumor associated with...
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Sustained North Atlantic warming drove anomalously intense MIS 11c interglacial
The Marine Isotope Stage (MIS) 11c interglacial and its preceding glacial termination represent an enigmatically intense climate response to...
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Utility of the web excision with pre-membranous incision for congenital intestinal atresia-type I and stenosis
PurposeThis study analyzed the efficacy of web excision combined with a pre-membranous incision on the dilated proximal segment for congenital...
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LINE1-mediated epigenetic repression of androgen receptor transcription causes androgen insensitivity syndrome
Androgen insensitivity syndrome (AIS) is a difference of sex development (DSD) characterized by different degrees of undervirilization in individuals...