Search
Search Results
-
Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results
Adoptive cell transfer (ACT) with neoantigen-reactive T lymphocytes can mediate cancer regression. Here we isolated unique, personalized,...
-
miPEP31 alleviates Ang II-induced hypertension in mice by occupying Cebpα binding sites in the pri-miR-31 promoter
BackgroundPrevious studies have shown that peptides encoded by noncoding RNAs (ncRNAs) can be used as peptide drugs to alleviate diseases. We found...
-
Ensuring People Living with HIV Inform the Future of HIV Treatment in Low- and Middle-Income Countries: A Sco** Review and Recommendations for a Community-Led Research Agenda
The HIV treatment landscape in low- and middle-income countries (LMICs) is rapidly evolving, exemplified by the expansion of differentiated service...
-
Paclitaxel in colon cancer management: from conventional chemotherapy to advanced nanocarrier delivery systems
Paclitaxel, a potent chemotherapeutic agent derived from the bark of the Pacific yew tree, has demonstrated significant efficacy in the treatment of...
-
The relationship between Stroma AReactive Invasion Front Areas (SARIFA), Warburg-subtype and survival: results from a large prospective series of colorectal cancer patients
BackgroundStroma AReactive Invasion Front Areas (SARIFA) is a recently identified haematoxylin & eosin (H&E)based histopathologic biomarker in...
-
Attention-based cross-frequency graph convolutional network for driver fatigue estimation
Fatigue driving significantly contributes to global vehicle accidents and fatalities, making driver fatigue level estimation crucial....
-
-
A consensus statement from the Japan Diabetes Society (JDS): a proposed algorithm for pharmacotherapy in people with type 2 diabetes—2nd Edition (English version)
The Japan Diabetes Society (JDS) adopted a swee** decision to release consensus statements on relevant issues in diabetes management that require...
-
miR-126a-5p inhibits H1N1-induced inflammation and matrix protease secretion in lung fibroblasts by targeting ADAMTS-4
Upregulation of ADAMTS-4 has been reported to have an important role in lung injury, and ADAMTS-4 expression is regulated by miR-126a-5p in abdominal...
-
Regulation of MicroRNAs After Spinal Cord Injury in Adult Zebrafish
Spinal cord injury (SCI) is a central nerve injury that often leads to loss of motor and sensory functions at or below the level of the injury....
-
The Association Between Autism Symptomatology and Adaptive Functioning Over Six Months: Findings from the Pilot Phase of the PARC Study
PurposeIn the context of developmental trajectories, the association between adaptive functioning and core autism symptomatology remains unclear. The...
-
Patterns of Pregabalin Users from Substance Abuse Treatment Facilities: Results from the French OPPIDUM Program from 2008 to 2022
IntroductionIn recent years, pregabalin has received growing attention due to its abuse liability. The aim of this study was to further characterize...
-
Positive parental history of diabetes is associated with early diagnosis, better dietary compliance, and glycemic control among type 2 diabetes patients in southern Sri Lanka
BackgroundParental history of diabetes is an established risk factor for type 2 diabetes mellitus (T2DM). There is limited data on the association of...
-
Coronavirus disease 2019 vaccination acceptance and associated factors among residents of Dire Dawa Administration, Eastern Ethiopia: a community-based cross-sectional study
BackgroundCorona virus disease 2019 (COVID-19) is an extremely contagious viral infection caused by the severe acute respiratory syndrome coronavirus...
-
Efficacy of Interceptor G2, Royal Guard and PermaNet 3.0 against pyrethroid-resistant Anopheles gambiae s.l. from Za-Kpota, southern Benin: an experimental hut trial
BackgroundThe widespread use of insecticide-treated nets (ITNs) has significantly contributed to the reduction in malaria cases and deaths observed...
-
Heterogeneity in choice models of addiction: the role of context
RationaleTheories of addiction guide scientific progress, funding priorities, and policy development and ultimately shape how people experiencing or...
-
Clinical and microbiological features of positive blood culture episodes caused by non-fermenting gram-negative bacilli other than Pseudomonas and Acinetobacter species (2020–2023)
IntroductionNon-fermenting Gram-negative bacilli (NFGNB) other than Pseudomonas aeruginosa and Acinetobacter baumannii complex are pathogens of...
-
Surgery on admission and following day reduces hip fracture complications: a Japanese DPC study
IntroductionThe efficacy of early surgery in preventing complications among Japanese elderly patients with hip fractures requires further...
-
Self-care practice and associated factors among patients with diabetes on follow-up at Yirgalem General Hospital, Sidama, Ethiopia: a cross-sectional study
BackgroundSelf-care practice is an integral and efficient part of comprehensive diabetes management, which could be influenced by various...
-
Sex-dependent association of serum vitamin D with muscle strength in older adults: NHANES 2001–2002
BackgroundAlthough several studies have suggested a potential positive association between serum vitamin D levels and muscle strength in older...