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Delirium in Neurocritical Care: Uncovering Undisclosed Psychotropic Substance and Medication Use and Stress Exposure by Hair Analysis
ObjectiveIn intensive care, delirium is frequent, prolongs the stay, increases health care costs, and worsens patient outcome. Several substances and...
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Inflammatory response of leptomeninges to a single cortical spreading depolarization
BackgroundNeurogenic meningeal inflammation is regarded as a key driver of migraine headache. Multiple evidence show importance of inflammatory...
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Safety and Psychological Outcomes of Tandem t:Slim X2 Insulin Pump with Control-IQ Technology in Children, Adolescents, and Young Adults with Type 1 Diabetes: A Systematic Review
The Tandem t:slim X2 insulin pump is a second-generation automated insulin delivery system with Control-IQ technology. It consists of an X2 insulin...
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Tirzepatide Improved Health-Related Quality of Life Compared with Insulin Lispro in Basal Insulin-Treated Adults with Type 2 Diabetes and Inadequate Glycaemic Control: A Randomised Controlled Phase 3b Trial (SURPASS-6)
IntroductionPatients with type 2 diabetes (T2D) who require intensification of basal insulin therapy need treatment options that can improve their...
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Clinical management protocols for community pharmacist-led management of urinary tract infections: a review of the grey literature and quality appraisal
BackgroundPharmacist-led management of urinary tract infections has been introduced as a service in the United Kingdom, Canada, United States of...
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Association of Changes in A1C Following Continuous Glucose Monitoring Acquisition in People with Sub-Optimally Treated Type 2 Diabetes Taking GLP-1 RA Therapy
IntroductionBoth glucagon-like peptide-1 receptor agonists (GLP-1 RA) and continuous glucose monitoring (CGM) improve glycemia in patients with type...
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Analysis of bacteraemia caused by group C and G Streptococcus (Streptococcus dysgalactiae subsp. equisimilis) in Western Sydney over a 6-year period (2015–2020)
PurposeStreptococcus dysgalactiae subsp. equisimilis (SDSE) has increasingly been recognised as a significant pathogen that causes a myriad of...
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Orale Antikoagulation bei supraventrikulären Rhythmusstörungen
Atrial fibrillation represents the most frequent persistent cardiac arrhythmia and is associated with an increased morbidity and mortality. An...
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Vorhofflimmern und Herzinsuffizienz
Atrial fibrillation and heart failure are among the most common cardiovascular diseases and have a significant impact on the mortality and morbidity...
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Are we informing our patients correctly? Evaluation of perioperative counselling for paediatric intestinal stoma formation: a national study
PurposeAdequate preoperative information is known to improve patient outcomes. We aimed to evaluate perioperative education for paediatric patients...
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CD147 TagSNP is associated with the vulnerability to lung cancer in the Chinese population: a case–control study
BackgroundLung cancer, with its high morbidity and mortality, presents a major significant public health challenge. CD147, linked to cancer...
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Photoactive metabolite mediated photodynamic therapy of Rhabdomyosarcoma cell lines using medicinal plants and Doxorubicin co-treatments
BackgroundMedicinal plant-mediated combinational therapies have gained importance globally due to minimal side effects and enhanced treatment...
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Predictors of medical adherence following a bowel management program for youth and young adults with Spina Bifida
PurposeTo evaluate individual and community sociodemographic factors that predict bowel regimen adherence in youth and young adults with Spina Bifida...
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The Impact of Lebrikizumab on Vaccine-Induced Immune Responses: Results from a Phase 3 Study in Adult Patients with Moderate-to-Severe Atopic Dermatitis
IntroductionLebrikizumab, a high-affinity IgG4 monoclonal antibody that selectively inhibits interleukin-13 with high binding affinity and slow...
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COPD, PRISm and lung function reduction affect the brain cortical structure: a Mendelian randomization study
Chronic obstructive pulmonary disease (COPD) has been associated with alterations in the brain cortical structure. Nonetheless, the causality between...