Search
Search Results
-
Anti-IL-17 Inhibits PINK1/Parkin Autophagy and M1 Macrophage Polarization in Rheumatic Heart Disease
Rheumatic heart disease (RHD) is an important and preventable cause of cardiovascular death and disability, but the lack of clarity about its exact...
-
-
Renal epithelioid angiomyolipomas overexpress TFE3 and the TFE3-regulated gene TRIM63 in the absence of TFE3 rearrangement
Angiomyolipoma (AML) is a neoplasm within the perivascular epithelioid cell tumor family that occurs somewhat frequently in the kidney. Most are...
-
CT in musculoskeletal imaging: still helpful and for what?
Computed tomography (CT) is a common modality employed for musculoskeletal imaging. Conventional CT techniques are useful for the assessment of...
-
MUC5AC immunoreactivity in scattered tumor cells is useful for diagnosing CIC-rearranged sarcoma
CIC -rearranged sarcoma is an aggressive round cell sarcoma, and an alternative ATXN1/ATXN1L fusion has been reported. Diagnosis may be difficult, and...
-
-
A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens
Understanding the interplay of the proteome and the metabolome helps to understand cellular regulation and response. To enable robust inferences from...
-
Infectious mononucleosis complicated by transitory Epstein-Barr virus infection of T and natural killer cells
Epstein-Barr virus (EBV) typically infects B cells in infectious mononucleosis (IM), but a rare case shows EBV infection in T cells. Seven cases of...
-
Trypanocidal resistance in two cattle farms using varying diagnostic techniques in southwest Nigeria
African animal trypanosomosis (AAT) affects the livestock industry, impacting protein intake and herders’ livelihoods. Despite the presence of vector...
-
Cancer stem cells: advances in knowledge and implications for cancer therapy
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-renewal and continuous proliferation, lead to...
-
Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka
BackgroundCharacterization of the host response in cutaneous leishmaniasis (CL) through proteome profiling has gained limited insights into...
-
Combining morphological and functional imaging parameters to diagnose primary bone neoplasms in the skull base, spine and sacrum
PurposeMorphological magnetic resonance (MR) and computed tomography (CT) features are used in combination with histology for diagnosis and treatment...
-
Clinicopathological characteristics and prognosis of uterine sarcoma: a 10-year retrospective single-center study in China
BackgroundUterine sarcoma is a rare and heterogeneous gynecological malignancy characterized by aggressive progression and poor prognosis. The...
-
Evaluating the performance of two different chemiluminescence analyzers systems in screening donors’ samples for HCV infection
BackgroundThe approved screening test for HCV infection among blood donors is the HCV antibody test. The diagnostic performances of the available...
-
Molecular alterations and prognosis of breast cancer with cutaneous metastasis
PurposeCutaneous metastasis (CM) accounts for 5–30% of patients with breast cancer (BC) and presents unfavorable response to treatment and poor...
-
A phase-I study of second-line S-IROX for unresectable pancreatic cancer after gemcitabine plus nab-paclitaxel failure
Gemcitabine plus nab-paclitaxel (GnP) and FOLFIRINOX are widely used as first-line regimens for unresectable pancreatic cancer (PC). When GnP therapy...
-
Comprehensive multiomics analysis of the signatures of gastric mucosal bacteria and plasma metabolites across different stomach microhabitats in the development of gastric cancer
PurposeAs an important component of the microenvironment, the gastric microbiota and its metabolites are associated with tumour occurrence,...
-
Cardiac rhabdomyoma: an uncommon culprit in sudden infant death
Sudden death in infants remains a common and poorly understood cause of childhood mortality in the USA. Pediatric cardiac tumors, although rare, may...
-
Sodium Houttuyfonate Ameliorates DSS-induced Colitis Aggravated by Candida albicans through Dectin-1/NF-κB/miR-32-5p/NFKBIZ Axis Based on Intestinal microRNA Profiling
Our previous research indicated that Sodium houttuyfonate (SH) can effectively ameliorate dextran sulfate sodium (DSS)-induced colitis exacerbated by C...
