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  1. Analysis and Architecture of Clinical Workflow Systems using Agent-Oriented Lifecycle Models

    Healthcare executives are grappling with a climate of great change in the healthcare industry. This is coming from a number of sources. First, there...
    James P. Davis, Raphael Blanco in Intelligent Paradigms for Healthcare Enterprises
    Chapter
  2. Current Status of Computerized Decision Support Systems in Mammography

    Breast cancer is one of the most devastating and deadly diseases for women today. Despite advances in cancer treatment, early mammographic detection...
    Chapter
  3. Computerization of Clinical Guidelines: an Application of Medical Document Processing

    Clinical Guidelines are being developed as a tool to promote Best Practice in Medicine. They are usually defined as “systematically developed...
    Chapter
  4. Case-based Medical Informatics

    The “applied” nature distinguishes applied sciences from theoretical sciences. To emphasize this distinction, we begin with a general, meta-level...
    Stefan V. Pantazi, José F. Arocha, Jochen R. Moehr in Intelligent Paradigms for Healthcare Enterprises
    Chapter
  5. Medical Diagnosis and Prognosis Based on the DNA Microarray Technology

    Immense genomic data have been accumulated through various research activities such as the Human Genome Project. A genome is the entire collection of...
    Y. Fukuoka, H. Inaoka, I. S. Kohane in Intelligent Paradigms for Healthcare Enterprises
    Chapter
  6. Wearable Devices in Healthcare

    The miniaturization of electrical and electronic equipment is certainly not a new phenomenon, and its effects have long been evident in the...
    Constantine Glaros, Dimitrios I. Fotiadis in Intelligent Paradigms for Healthcare Enterprises
    Chapter
  7. Evidence Based Telemedicine

    This chapter focuses on evidence based telemedicine and its various applications. Evidence based medicine is the integration of best research...
    George Anogianakis, Anelia Klisarova, ... Antonia Anogeianaki in Intelligent Paradigms for Healthcare Enterprises
    Chapter
  8. Virtual Communities in Health Care

    A virtual community is a social entity involving several individuals who relate to one another by the use of a specific communication technology that...
    Chapter
  9. A position-enhanced sequential feature encoding model for lung infections and lymphoma classification on CT images

    Purpose

    Differentiating pulmonary lymphoma from lung infections using CT images is challenging. Existing deep neural network-based lung CT...

    Article 14 July 2024
  10. What to Measure in Aneurysmal Subarachnoid Haemorrhage Research—An International Delphi Survey

    Aneurysmal subarachnoid haemorrhage (aSAH) is a devastating condition with high mortality and morbidity. The outcome measures used in aSAH clinical...

    Christopher R. Andersen, Justin Presseau, ... Shane W. English in Translational Stroke Research
    Article 13 July 2024
  11. Physiological and cellular mechanisms of ischemic preconditioning microRNAs-mediated in underlying of ischemia/reperfusion injury in different organs

    Ischemia–reperfusion (I/R) injury, as a pathological phenomenon, takes place when blood supply to an organ is disrupted and then aggravated during...

    Izadpanah Gheitasi, Ghaidafeh Akbari, Feryal Savari in Molecular and Cellular Biochemistry
    Article 13 July 2024
  12. Needle tracking in low-resolution ultrasound volumes using deep learning

    Purpose

    Clinical needle insertion into tissue, commonly assisted by 2D ultrasound imaging for real-time navigation, faces the challenge of precise...

    Sarah Grube, Sarah Latus, ... Alexander Schlaefer in International Journal of Computer Assisted Radiology and Surgery
    Article Open access 13 July 2024
  13. Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission

    Dietary salt is increasingly recognized as an independent risk factor for cognitive impairment. However, the exact mechanisms are not yet fully...

    Haixia Fan, Minghao Yuan, ... Zhiyou Cai in Molecular and Cellular Biochemistry
    Article 13 July 2024
  14. Relationship between the severity of functional mitral regurgitation at admission and one-year outcomes in patients hospitalized for acute heart failure with mildly reduced ejection fraction

    Background

    The epidemiological distribution of functional mitral regurgitation (FMR) in heart failure (HF) and mildly reduced ejection fraction...

    Zhenhua Wang, Yue Zeng, ... Chaosheng Li in BMC Cardiovascular Disorders
    Article Open access 13 July 2024
  15. Signal drift in diffusion MRI of the brain: effects on intravoxel incoherent motion parameter estimates

    Objectives

    Signal drift has been put forward as one of the fundamental confounding factors in diffusion MRI (dMRI) of the brain. This study...

    Oscar Jalnefjord, Louise Rosenqvist, ... Isabella M. Björkman-Burtscher in Magnetic Resonance Materials in Physics, Biology and Medicine
    Article Open access 13 July 2024
  16. DNA Methylation-derived biological age and long-term mortality risk in subjects with type 2 diabetes

    Background

    Individuals with type 2 diabetes (T2D) face an increased mortality risk, not fully captured by canonical risk factors. Biological age...

    Jacopo Sabbatinelli, Angelica Giuliani, ... Giuseppe Bronte in Cardiovascular Diabetology
    Article Open access 13 July 2024
  17. Detection of pulmonary nodules in chest radiographs: novel cost function for effective network training with purely synthesized datasets

    Purpose

    Many large radiographic datasets of lung nodules are available, but the small and hard-to-detect nodules are rarely validated by computed...

    Shouhei Hanaoka, Yukihiro Nomura, ... Osamu Abe in International Journal of Computer Assisted Radiology and Surgery
    Article Open access 13 July 2024
  18. Breathing difficulties in a nonagenarian: a self report

    This is a self report. It is age related because I am 96 years old; about 5 years ago I was asymptomatic in this respect. I describe the difficulties...

    Otto Appenzeller in Clinical Autonomic Research
    Article 13 July 2024
  19. Lnc PVT1 facilitates TGF-β1-induced human cardiac fibroblast activation in vitro and ISO-induced myocardial fibrosis in vivo through regulating MYC

    Cardiac fibrosis is a commonly seen pathophysiological process in various cardiovascular disorders, such as coronary heart disorder, hypertension,...

    Juan Wang, Zhong-Yin Lv, ... Di-Fei Shen in Molecular and Cellular Biochemistry
    Article 13 July 2024
  20. Enhancing patient acceptance of ICD implantation through structured shared decision making: conversation is key

    Background

    Implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy defibrillators (CRT-D) are lifesaving treatments for...

    Litsa K. Lambrakos, Suzanne A. Feigofsky, ... Jonathan C. Hsu in Journal of Interventional Cardiac Electrophysiology
    Article Open access 13 July 2024
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