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  1. Association of cord blood Ang-1 and sCD105 levels with bronchopulmonary dysplasia in preterm infants

    Background

    To investigate the relationship between cord blood levels of Angiopoietin-1 (Ang-1) and S-endoglin (sCD105) and bronchopulmonary dysplasia...

    **gyun Yang, Yun Wang, ... Lizhen Wang in BMC Pediatrics
    Article Open access 15 July 2024
  2. Pharmacodynamic Comparison of Two Aspirin Formulations in the Caribbean: The ARC Study

    Introduction

    This prospective, single-arm, crossover pharmacodynamic study assessed the effect of Bayer ® low-dose enteric-coated aspirin 81 mg...

    Naveen Seecheran, Penelope McCallum, ... Sherry Sandy in Cardiology and Therapy
    Article Open access 15 July 2024
  3. Mavorixafor: First Approval

    Mavorixafor (XOLREMDI™) is an oral, selective C-X-C chemokine receptor 4 (CXCR4) antagonist developed by X4 Pharmaceuticals that blocks the binding...

    Sheridan M. Hoy in Drugs
    Article 15 July 2024
  4. Detection and characterization of autoreactive memory stem T-cells in children with acute immune thrombocytopenia

    Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by an isolated decrease in platelets below 100 × 10 9 /l after...

    Asmaa M. Zahran, Omnia H. El-Badawy, ... Khalid I. Elsayh in Clinical and Experimental Medicine
    Article Open access 15 July 2024
  5. Efficacy and Safety of Salvage-line Nivolumab Monotherapy for Advanced Esophageal Squamous Cell Carcinoma: Comparison of 240 mg Versus 480 mg Doses

    Background

    Nivolumab monotherapy is the standard second-line treatment for advanced esophageal squamous cell carcinoma (ESCC) after failure of...

    Yuko Murashima, Shun Yamamoto, ... Ken Kato in Journal of Gastrointestinal Cancer
    Article Open access 15 July 2024
  6. Evaluating [225Ac]Ac-FAPI-46 for the treatment of soft-tissue sarcoma in mice

    Purpose

    Fibroblast Activation Protein (FAP) is an emerging theranostic target that is highly expressed on cancer-associated fibroblasts and on certain...

    Marco F. Taddio, Suraj Doshi, ... Christine E. Mona in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 15 July 2024
  7. Effect of dorsal capsular imbrication on intraoperative DRUJ instability following arthroscopic TFCC repair surgery

    Background

    To assess the clinical outcomes and identify the ideal indication for implementing dorsal distal radioulnar joint (DRUJ) capsular...

    Chen-Wei Yeh, Cheng-En Hsu, ... Yung-Cheng Chiu in BMC Musculoskeletal Disorders
    Article Open access 15 July 2024
  8. Evaluation of the clinical efficacy of using an inverted triangular cannulated compression screw in combination with positive or negative buttress reduction for the healing of femoral neck fractures

    Objective

    We aimed to compare the clinical efficacy of inverted triangular cannulated compression screws combined with Gotfried positive or negative...

    Gang Wang, Cui Tang, ... Gaokai Li in BMC Musculoskeletal Disorders
    Article Open access 15 July 2024
  9. Global longitudinal active strain energy density (GLASED): age and sex differences between young and veteran athletes

    Background

    Global longitudinal active strain energy density (GLASED) is an innovative method for assessing myocardial function and quantifies the work...

    David H. MacIver, Henggui Zhang, ... David Oxborough in Echo Research & Practice
    Article Open access 15 July 2024
  10. Epidemiology, outcomes and prognosis of infective endocarditis in Northern Morocco

    Introduction

    Infective endocarditis is a rare but potentially severe disease, associated with significant morbidity and mortality. Our study aims to...

    Badre El Boussaadani, Ilias Soussan, ... Zainab Raissuni in BMC Infectious Diseases
    Article Open access 15 July 2024
  11. Impact on Glycemia Risk Index and other metrics in type 1 adult patients switching to Advanced Hybrid Closed-Loop systems: a one-year real-life experience

    Background

    Advanced Hybrid Closed-Loop system (AHCL) has profoundly changed type 1 diabetes therapy. This study primarily aimed to assess the impact...

    Eugenia Resmini, Emanuela Zarra, ... Angela Girelli in European Journal of Medical Research
    Article Open access 15 July 2024
  12. Development of a novel approach for restoration of the meniscus using silk-elastin in a rabbit meniscus injury model

    Background

    Limited healing potential of the meniscus remains a burden for the successful repair of meniscus injuries in the orthopaedic fields....

    Tadashi Inoue, Toshiya Kano, ... Nobuo Adachi in BMC Musculoskeletal Disorders
    Article Open access 15 July 2024
  13. Changes in the anteroposterior position of the femur relative to the tibia impact patient satisfaction in total knee arthroplasty

    Background

    In this study, we aimed to investigate the preoperative and postoperative anteroposterior position (AP) of the femur relative to the tibia...

    Tomofumi Kinoshita, Kazunori Hino, ... Masaki Takao in BMC Musculoskeletal Disorders
    Article Open access 15 July 2024
  14. Anticholinergic burden and health-related quality of life among adult patients in a resource-limited setting: a cross-sectional study

    Background

    Anticholinergic medications are now widely acknowledged for their unfavorable risk-to-benefit profile owing to their adverse effects....

    Eyob Alemayehu Gebreyohannes, Biniam Siyum Shibe, ... Roy Louis Soiza in International Journal of Clinical Pharmacy
    Article Open access 15 July 2024
  15. Efficacy and safety of rechallenge [177Lu]Lu-PSMA-617 RLT after initial partial remission in patients with mCRPC: evaluation of a prospective registry (REALITY study)

    Aim

    Rechallenge of [ 177 Lu]Lu-PSMA-617 radioligand therapy (RLT) was proposed for patients who initially responded to PSMA-RLT experiencing partial...

    Florian Rosar, Joelle Schuler, ... Samer Ezziddin in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 15 July 2024
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