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Peptides for microbe-induced cancers: latest therapeutic strategies and their advanced technologies
Cancer is a significant global health concern associated with multiple distinct factors, including microbial and viral infections. Numerous studies...
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DBScope as a versatile computational toolbox for the visualization and analysis of sensing data from deep brain stimulation
Different neurostimulators for deep brain stimulation (DBS) come already with the ability to chronically sense local field potentials during...
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Gastric band removal: mind the arterial anastomoses!
Bariatric surgery may sometimes be challenging and may lead to severe complications. Surgical re-intervention in such cases is not the preferred...
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Resveratrol-based nano-formulations as an emerging therapeutic strategy for ovarian carcinoma: autophagy stimulation and SIRT-1/Beclin/MMP-9/P53/AKT signaling
BackgroundResveratrol (RVS) is a stilbene derivative polyphenolic compound extensively recognized for its anti-inflammatory, antioxidant and...
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Challenges in the diagnosis and treatment of pure non-gestational uterine choriocarcinoma in a child: a case report
BackgroundDiagnosing non-gestational uterine choriocarcinoma in children is challenging because of its rarity and nonspecific imaging findings....
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Fluorescence Studies on the Binding Affinity and Determination of Vitamin B12 in the Presence of Fibrinogen
The binding properties between vitamin B12 (vitB12, cyanocobalamin) and fibrinogen (Fib) were investigated by UV-vis absorption and...
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Current trends and future perspectives in hadron therapy: radiobiology
PurposeThe purpose of this article was to highlight current and future trends in radiobiology in an effort to move hadron therapy forward through the...
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Panorama of Odontogenic Tumours and Cystic Lesions of Jaw: A Single Institutional Experience
Odontogenic tumours are relatively rare tumours presenting with varied behaviour ranging from hamartomatous lesion to malignant neoplasm. Majority of...
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Consumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial
Consumer-grade wearable technology has the potential to support clinical research and patient management. Here, we report results from the RATE-AF...
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A nonoscillatory, millisecond-scale embedding of brain state provides insight into behavior
The most robust and reliable signatures of brain states are enriched in rhythms between 0.1 and 20 Hz. Here we address the possibility that the...
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Unlocking opioid neuropeptide dynamics with genetically encoded biosensors
Neuropeptides are ubiquitous in the nervous system. Research into neuropeptides has been limited by a lack of experimental tools that allow for the...
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The immunology of systemic lupus erythematosus
Understanding the pathogenesis and clinical manifestations of systemic lupus erythematosus (SLE) has been a great challenge. Reductionist approaches...
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HIV1 drug resistance among patients experiencing first-line treatment failure in Ethiopia: protocol for a systematic review and meta-analysis
BackgroundThe emergence of HIV drug resistance presents a substantial challenge. Current antiretroviral treatments, along with current classes, face...
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Deep source transfer learning for the estimation of internal brain dynamics using scalp EEG
Electroencephalography (EEG) provides high temporal resolution neural data for brain-computer interfacing via noninvasive electrophysiological...
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Efficacy of chemotherapy plus immune checkpoint inhibitors in patients with non-small cell lung cancer who have rare oncogenic driver mutations: a retrospective analysis
BackgroundTargeted therapy is now the standard of care in driver–oncogene-positive non-small cell lung cancer (NSCLC). Its initial clinical effects...
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Ile-Pro-Pro attenuates sympathetic activity and hypertension
Isoleucine-proline-proline (Ile-Pro-Pro, IPP) is a natural food source tripeptide that inhibits angiotensin-converting enzyme (ACE) activity. The aim...
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Epithelial to Mesenchymal Transition in Neuroblastoma: Mechanisms and Therapeutic Considerations
Purpose of ReviewNeuroblastoma (NB) is a solid tumour of the extracranial region in children, and it originates from the develo** sympathetic...
