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The Porous SilMA Hydrogel Scaffolds Carrying Dual-Sensitive Paclitaxel Nanoparticles Promote Neuronal Differentiation for Spinal Cord Injury Repair
BACKGROUND: In the intricate pathological milieu post-spinal cord injury (SCI), neural stem cells (NSCs) frequently differentiate into astrocytes...
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Platelet-Rich Plasma Promotes the Expansion of Human Myoblasts and Favors the In Vitro Generation of Human Muscle Reserve Cells in a Deeper State of Quiescence
Stem cell therapy holds significant potential for skeletal muscle repair, with in vitro-generated human muscle reserve cells (MuRCs) emerging as a...
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The Angiogenic Repertoire of Stem Cell Extracellular Vesicles: Demystifying the Molecular Underpinnings for Wound Healing Applications
Stem cells-derived extracellular vesicles (SC-EVs) have emerged as promising therapeutic agents for wound repair, recapitulating the biological...
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PET Images Enhancement Using Deep Training of Reconstructed Images with Bayesian Penalized Likelihood Algorithm
PurposeTo adopt the merits of the Bayesian Penalized Likelihood (BPL) reconstruction algorithm (incl. improved contrast recovery), a deep learning...
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Modified mesenchymal stromal cells by in vitro transcribed mRNA: a therapeutic strategy for hepatocellular carcinoma
BackgroundMesenchymal stromal cells (MSCs) tropism for tumours allows their use as carriers of antitumoural factors and in vitro transcribed mRNA...
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On the Kinematics of Growth of Regular Boundaries of Bodies into Fractals
Generalizing smooth volumetric growth to the singular case, using de Rham currents and flat chains, we demonstrate how regular boundaries of bodies...
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Autotaxin Inhibition Reduces Post‐Ischemic Myocardial Inflammation via Epigenetic Gene Modifications
Myocardial infarction (MI) triggers a complex inflammatory response that is essential for cardiac repair but can also lead to adverse outcomes if...
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A Second-Order Multiscale Model for Finite-Strain Poromechanics Based on the Method of Multiscale Virtual Power
A second-order multiscale theory based on the concept of a Representative Volume Element (RVE) is proposed to link a classical poromechanical model...
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Axisymmetric Contact Problem for a Homogeneous Space with a Circular Disk-Shaped Crack Under Static Friction
The paper considers an axisymmetric stress state of a homogeneous elastic space with a circular disc-shaped crack, one of the edges of which is...
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Possible Drug Repurposing and Accelerated Wound Healing
PurposeHealing of a wound is a multifaceted process that involves several factors to be considered for proper completion. Improper healing of wounds...
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Applications of extraembryonic tissue-derived cells in vascular tissue regeneration
Vascular tissue engineering is a promising approach for regenerating damaged blood vessels and develo** new therapeutic approaches for heart...
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Antibacterial, Antioxidant, and Healing Potential of Wound Dressings Utilizing Cranberry Extract in Combination with Methacrylated Polyvinyl Alcohol and Methacrylated Sericin
PurposeHydrogels, due to their hydrophilic nature and tunable properties, have emerged as promising materials for wound dressings. Notably, the...
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The roles of neural stem cells in myelin regeneration and repair therapy after spinal cord injury
Spinal cord injury (SCI) is a complex tissue injury that results in a wide range of physical deficits, including permanent or progressive...
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Extracellular Microvesicles vs. Mitochondria: Competing for the Top Spot in Cardiovascular Regenerative Medicine
Regenerative medicine aims to restore, replace, and regenerate human cells, tissues, and organs. Despite significant advancements, many cell therapy...
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Extracellular Vesicles from Adipose Tissue-Derived Stromal Cells Stimulate Angiogenesis in a Scaffold-Dependent Fashion
Background:The extracellular vesicles (EVs) secreted by adipose tissue-derived stromal cells (ASC) are microenvironment modulators in tissue...
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IRTKS Elevation in Patients with Colon Cancer and the Curative Influences of Hamsc Secretome on Polarity and Invasion of HT-29 Colon Cancer Cells
PurposeColon cancer is a major contributor (fifth one) to cancer-related deaths in the world. For the unique characteristics of stem cells, stem...
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Role of Neurotransmitters in Steady State Hematopoiesis, Aging, and Leukemia
Haematopoiesis within the bone marrow (BM) represents a complex and dynamic process intricately regulated by neural signaling pathways. This delicate...
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Preclinical Therapeutic Efficacy of Extracellular Vesicles Derived from Adipose-Derived Mesenchymal Stromal/Stem Cells in Diabetic Wounds: a Systematic Review and Meta-Analysis
Extracellular vesicles isolated from adipose tissue-derived mesenchymal stromal/stem cells (ADSC-EVs) have demonstrated promising potential in wound...
