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  1. Deconvolution Microscopy

    Since its introduction in 1983, deconvolution microscopy has become a key image-processing tool for visualizing the cellular structures of fixed and...
    Jean-Baptiste Sibarita in Microscopy Techniques
    Chapter
  2. Spectral Imaging and Linear Unmixing in Light Microscopy

    Fluorescence microscopy is an essential tool for modern biological research. The wide range of available fluorophores and labeling techniques allows...
    Timo Zimmermann in Microscopy Techniques
    Chapter
  3. Total Internal Reflection Fluorescence Microscopy in Single Molecule Nanobioscience

    Recent development in total internal reflection fluorescence microscopy (TIRFM) has made it possible to directly monitor the behaviors of...
    Tetsuichi Wazawa, Masahiro Ueda in Microscopy Techniques
    Chapter
  4. Fluorescence Lifetime Imaging Microscopy (FLIM)

    Fluorescence lifetime imaging microscopy (FLIM) is a technique to map the spatial distribution of nanosecond excited state lifetimes within...
    Erik B. van Munster, Theodorus W. J. Gadella in Microscopy Techniques
    Chapter
  5. Higher Harmonic Generation Microscopy

    Higher harmonic-generation, including second harmonic generation and third harmonic generation, leaves no energy deposition to the interacted matters...
    Chi-Kuang Sun in Microscopy Techniques
    Chapter
  6. Tracking Movement in Cell Biology

    This article is an overview of techniques for measuring movement of proteins, vesicles and cells using digital image processing. Diverse techniques...
    Kota Miura in Microscopy Techniques
    Chapter
  7. Current Topics Regarding the Function of the Medial Temporal Lobe Memory System

    The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
    Chapter
  8. Fluorescence Correlation Spectroscopy with Autofluorescent Proteins

    Fluorescence correlation spectroscopy (FCS) is a versatile technique operating at the single-molecule level, that successfully meets many challenges...
    Tobias Kohl, Petra Schwille in Microscopy Techniques
    Chapter
  9. Engineering Fluorescent Proteins

    Green fluorescent protein from the jellyfish Aequorea victora (GFP) and GFP-like proteins from Anthozoa species encode light-absorbing chromophores...
    Atsushi Miyawaki, Takeharu Nagai, Hideaki Mizuno in Microscopy Techniques
    Chapter
  10. Live Cell Spinning Disk Microscopy

    In vivo microscopy of dynamic processes in cells and organisms requires very fast and sensitive acquisition methods. Confocal laser scanning...
    Ralph Gräf, Jens Rietdorf, Timo Zimmermann in Microscopy Techniques
    Chapter
  11. Fluorescence Recovery after Photobleaching: Application to Nuclear Proteins

    Fluorescence redistribution after photobleaching (FRAP) has received increasing attention ever since it was first introduced into cell biological...
    Adriaan B. Houtsmuller in Microscopy Techniques
    Chapter
  12. Embelin Mitigates Amyloid-β-Induced Neurotoxicity and Cognitive Impairment in Rats: Potential Therapeutic Implications for Alzheimer’s Disease

    Alzheimer’s disease (AD) is a significant form of dementia. Embelin (EMB) is a natural compound with varied actions that could help prevent AD...

    Rimpi Arora, Rahul Deshmukh in Molecular Neurobiology
    Article 15 July 2024
  13. FABP3 Induces Mitochondrial Autophagy to Promote Neuronal Cell Apoptosis in Brain Ischemia-Reperfusion Injury

    This study elucidates the molecular mechanisms by which FABP3 regulates neuronal apoptosis via mitochondrial autophagy in the context of cerebral...

    Fang-Fang Zhong, Bo Wei, ... **-** Tian in Neurotoxicity Research
    Article 15 July 2024
  14. Generation of musculoskeletal cells from human urine epithelium-derived presomitic mesoderm cells

    Background

    Numerous studies have shown that somite development is a necessary stage of myogenesis chondrogenesis and osteogenesis. Our previous study...

    Huiru Gao, **ngnan Huang, ... Duanqing Pei in Cell & Bioscience
    Article Open access 15 July 2024
  15. Synthesis and Neurobehavioral Evaluation of a Potent Multitargeted Inhibitor for the Treatment of Alzheimer’s Disease

    Alzheimer’s disease (AD) poses a significant health challenge worldwide, affecting millions of individuals, and projected to increase further as the...

    Mohd Shahnawaz Khan, Zuber Khan, ... Shams Tabrez in Molecular Neurobiology
    Article 15 July 2024
  16. Mechanisms of stationary voltage fluctuation in the neuromuscular junction endplate and corresponding denoising paradigms

    The neuromuscular junction (NMJ) has an elaborate anatomy to ensure agile and accurate signal transmission. Based on our formerly obtained...

    Jia-Zeng Wang, Pengkun Hu, Shu Ma in European Biophysics Journal
    Article 15 July 2024
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