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Central nervous system involvement in chronic lymphocytic leukemia: a case report and review of literature
BackgroundCentral nervous system involvement in chronic lymphocytic leukemia rarely occurs, and there is no standard therapy for central nervous...
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The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site staff
BackgroundSharing trial results with participants is a moral imperative, but too often does not happen in appropriate ways.
MethodsWe carried out...
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PICC tip dislodgement causing massive pleural effusion and atelectasis with acute respiratory failure: a case report
Peripheral intravenous central catheter (PICC) is a common tool for intravenous infusion for children who need central venous access. Although it is...
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Zinc finger 259 gene polymorphisms in Egyptian patients with metabolic syndrome and its association with dyslipidemia
BackgroundZinc finger protein 1 (ZPR1), encoded by the ZNF259 gene, plays crucial roles in transcriptional regulation and cell cycle progression....
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Conditional survival and the prognostic value of serum carcinoembryonic antigen level in oldest old with colorectal cancer
BackgroundTo evaluate the clinical value of serum CEA levels and their implications on the diagnostic value of the conventional TNM staging system in...
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A possible role of lncRNA MEG3 and lncRNA MAFG-AS1 on miRNA 147-b in the pathogenesis of Behcet’s disease
Behcet’s disease (BD) is a multisystem disease with altered Toll-like receptors (TLRs) on macrophages. Long noncoding RNA Maternally expressed gene 3...
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Randomized investigation of increased dialyzer membrane hydrophilicity on hemocompatibility and performance
BackgroundHemodialyzers should efficiently eliminate small and middle molecular uremic toxins and possess exceptional hemocompatibility to improve...
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Comparison of low versus high (standard) intraabdominal pressure during laparoscopic colorectal surgery: systematic review and meta-analysis
BackgroundTo evaluate outcomes of low with high intraabdominal pressure during laparoscopic colorectal resection surgery.
MethodsA systematic search...
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Refractory type 1 plastic bronchitis in a child; case report
BackgroundPlastic bronchitis (PB) is a rare pediatric pulmonary condition characterized by the production of branching bronchial casts that cause...
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Systems Biology: necessary developments and trends
At the end of this definition of Systems Biology through exampling, we discuss ambitions, goals, and challenges relating to this new discipline. We...
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From Classical Connectionist Models to Probabilistic/Generalised Regression Neural Networks (PNNs/GRNNs)
This chapter begins by briefly summarising some of the well-known classical connectionist/artificial neural network models such as multi-layered...
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Linkage Learning Genetic Algorithm
In order to handle linkage evolution and to tackle the ordering problem, Harik [47] took Holland’s call [53] for the evolution of tight linkage quite...
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Preliminaries: Assumptions and the Test Problem
After introducing the background and motivation of the linkage learning genetic algorithm, we will start to improve and understand the linkage...
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Data Driven Fuzzy Modelling with Neural Networks
Extraction of models for complex systems from numerical data of behavior is studied. In particular, systems representable as sets of fuzzy if-then...
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Bioinformatics with Evolutionary Computation
This chapter makes the presumption that it is more important to understand the domain of the problem of interest and to pursue the best achievable...
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Rough Set Theory with Applications to Data Mining
This paper is an introduction to rough set theory with an emphasis on applications to data mining. First, consistent data are discussed, including...
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The Kernel Memory Concept – A Paradigm Shift from Conventional Connectionism
In this chapter, the general concept of kernel memory (KM) is described, which is given as the basis for not only representing the general notion of...
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Language and Thinking Modules
In this chapter, we focus upon the two modules which are closely tied to the concept of “action planning”, i.e. the 1) language and 2) thinking...
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Reinforcement Learning: A Brief Overview
Learning techniques can be usefully grouped by the type of feedback that is available to the learner. A commonly drawn distinction is that between...
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Sensation and Perception Modules
In any kind of creature, both the mechanisms of sensation and perception are indispensable for continuous living, e.g. to find edible plants/fruits...