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OBSERVE: guidelines for the refinement of rodent cancer models
Existing guidelines on the preparation (Planning Research and Experimental Procedures on Animals: Recommendations for Excellence (PREPARE)) and...
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Modulation of gene expression in immune-related organs by in ovo stimulation with probiotics and prophybiotics in broiler chickens
In ovo stimulation has been studied intensively as an alternative to antibiotic use in poultry production. We investigated the potential use of a...
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Analysis of the implementation of the certification of second-tier quality control in Taiwan food businesses and common non-conformities
The Taiwan Food and Drug Administration has implemented a three-tier quality control system to enhance food safety. This system includes...
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Herbidomicins, two pairs of polyketide tautomers produced by an actinomycete of the genus Herbidospora
Herbidospora is one of the underexplored actinomycete genera from which only a limited number of secondary metabolites are reported. In our...
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Diverse growth rates in Triassic archosaurs—insights from a small terrestrial Middle Triassic pseudosuchian
The small pseudosuchian Benggwigwishingasuchus eremacarminis was found in Anisian (Middle Triassic) marine sediments. Neither the skeleton nor...
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Rhizobacteria associated with Parkinsonia aculeata L. under semi desertic drought and saline conditions
Plants rhizosphere and bacterial communities’ association offer great advantages for its adaptation to adverse conditions in desert ecosystems. In...
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A roadmap for ribosome assembly in human mitochondria
Mitochondria contain dedicated ribosomes (mitoribosomes), which synthesize the mitochondrial-encoded core components of the oxidative phosphorylation...
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A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance
Despite tremendous progress in precision oncology, adaptive resistance mechanisms limit the long-term effectiveness of molecularly targeted agents....
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Human post-implantation blastocyst-like characteristics of Muse cells isolated from human umbilical cord
Muse cells, identified as cells positive for the pluripotent surface marker SSEA-3, are pluripotent-like endogenous stem cells located in the bone...
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Advancing stroke recovery: unlocking the potential of cellular dynamics in stroke recovery
Stroke stands as a predominant cause of mortality and morbidity worldwide, and there is a pressing need for effective therapies to improve outcomes...
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Biogenesis of specialized lysosomes in differentiated keratinocytes relies on close apposition with the Golgi apparatus
Intracellular organelles support cellular physiology in diverse conditions. In the skin, epidermal keratinocytes undergo differentiation with gradual...
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Synthetic macrolides overcoming MLSBK-resistant pathogens
Conventional macrolide-lincosamide-streptogramin B-ketolide (MLS B K) antibiotics are unable to counter the growing challenge of antibiotic resistance...
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Genome-wide analysis of histone modifications can contribute to the identification of candidate cis-regulatory regions in the threespine stickleback fish
BackgroundCis -regulatory mutations often underlie phenotypic evolution. However, because identifying the locations of promoters and enhancers in...
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New records of two jellyfish species Rhizostoma luteum (Quoy and Gaimard 1827) and Cotylorhiza tuberculata (Macri 1778) in the Moroccan northwest Mediterranean coast
During monitoring visits to the beaches of Fnideq, M'Diq, Cabo-Negro, and Martil, two jellyfish species along the Moroccan Northwest Mediterranean...
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Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic acid cycle and subsequent loss of iron-sulfur cluster...
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Correlation between bioluminescent blinks and swimming behavior in the splitfin flashlight fish Anomalops katoptron
BackgroundThe light organs of the splitfin flashlight fish Anomalops katoptron are necessary for schooling behavior, to determine nearest neighbor...
